Nitrogen limitation of CO2 fertilization: relief from fungal partners

New research shows that the stimulatory effect of atmospheric CO2 on plants depends on soil nitrogen and on the microbes that can help plants get it. More »

Using genome-scale models to predict biological capabilities

Rapid advances in DNA sequencing and synthesis technologies have revolutionized the study of life sciences. More »

Do plants have brains?

Many organisms have circadian clocks. These internal clocks play essential roles for predicting day-length or seasons, and they regulate behavior and hormonal secretion in animals More »

Zika virus infection during pregnancy and small heads: What is the connection and what can be seen by imaging

Within the last year, the outbreak of Zika virus infection in Brazil became a “public health emergency of international magnitude and concern”. More »

 

Arabinoxylan rice bran (Biobran) for the treatment of Hepatitis C

Hepatitis C virus (HCV) has infected approximately 150 million people world-wide (about 3% of the world population) and causes approximately 700,000 deaths each year.  It has been shown to be a causal factor of liver cirrhosis, scarring

Cases of trephination in ancient Armenia skulls

Trepanation of the cranial vault, one of the most intriguing paleoneurosurgical techniques. Trepanation has garnered intense interest, because it represents an early form of cranial surgery practiced well before the advent of modern medicine. Trepanning seems to

Are there genetically modified animals in the supermarket?

Animal breeders have used selective breeding, a form of directed evolution, since animals were first domesticated. Using this approach, individual animals are chosen to be parents of the next generation because they exhibit a desirable trait or

Fabrication of magnetic activated carbon as a new adsorbent for ultrasonic assisted magnetic solid phase dispersive extraction of bisphenol A from milk

Bisphenol A (BPA), is an organic chemical compound that has been widely used as a monomer in the manufacturing of polycarbonate plastics and epoxy resins, in thermal paper production and as an additive in the formation of

Can vitamin E protect cells from persistent organochlorine contaminants such as polychlorinated biphenyls?

Many toxic substances, mostly man-made, are present and widespread in our environment. Eventually they become a part of the food chain — e.g. pesticide residues, veterinary drugs and pharmaceuticals, contaminating substances originating from industrial processes – heavy

How its great therapeutic potential can finally be realized

Fibrinolysis refers to the body’s natural defense system against blood clots, which are made principally of a protein called fibrin. “Lysis” is the Greek word for dissolving, therefore, dissolving fibrin clots. Fibrinolysis is needed because clots are

A stone during pregnancy – more painful than childbirth

Kidney or ureter stones in pregnancy are a major health concern and are one of the most common causes for abdominal pain in pregnant women. Stones may lead to a blocked kidney, kidney infection which may spread

Could accelerated physical therapy after hip and knee replacement get patients home sooner?

The joint replacement procedures total hip arthroplasty (THA) and total knee arthroplasty (TKA) are among the most effective surgical procedures in modern medicine. In the United States the number of THA procedures is projected to increase 174%

Occupational causation of sarcoidosis

Sarcoidosis is an uncommon disorder of unknown cause characterized by widespread granulomas, a distinctive tissue response resembling that caused by tuberculosis. A number of articles have appeared within the past few years inferring occupational causation based on

Why are skeletal muscles not depleted of energy during intense exercise?

ATP is a universal carrier of energy in a form easily accessible for different reactions in the cell. Its hydrolysis to ADP and Pi (inorganic phosphate) drives processes that cannot occur spontaneously and require energy, for instance

Time to switch? Switching from innovator rituximab to biosimilar CT-P10 is safe and efficacious

Rituximab is a monoclonal antibody that targets the CD20 protein that is found mainly on immune cells called B lymphocytes. By removing CD20-positive B lymphocytes from the peripheral blood and bone marrow, rituximab provides effective treatment for

Non-canonical Wnt signaling and aortic valve stenosis

Even with the countless drugs we have to treat cardiovascular diseases, the majority of these diseases remain without a cure. Aortic valve stenosis (AVS) is one of these diseases, characterized by the narrowing of the aortic valve

p38α MAP kinase inhibition in atherosclerosis – a new therapeutic tool?

Atherosclerotic cardiovascular disease is the leading cause of mortality worldwide. Selective recruitment of monocytes into the arterial intima and their transformation into macrophage-derived foam cells is one of the earliest events in the pathogenesis of atherosclerosis. Foam

Why is the transcription factor Pax8 necessary for a functional thyroid gland?

By controlling the synthesis and secretion of thyroid hormones, the endocrine thyroid gland plays an important role in governing organismal development and metabolic homeostasis. The structural and functional unit of the thyroid gland is the thyroid follicle,

Hot or Not – The Heat Shock Factor1 (HSF1) is essential for Candida albicans cellular functioning

The opportunistic human pathogen, Candida albicans hinges on the heat shock factor-1 (HSF1), a client protein of the well-established heat shock chaperone (protein folding helper), HSP90 for proficiently modulating thermal stress response. In addition to its implications

Long-term safety and efficacy of rituximab biosimilar CT-P10 in rheumatoid arthritis

Rituximab is a monoclonal antibody used to treat certain cancers of the blood, as well as immune-mediated diseases such as rheumatoid arthritis. But while rituximab is effective, it is also expensive, which means that not everyone who