Sailfish: the fastest fish in the world?

The fascination for speed runs deep in humans: we are in awe of fast cars and the 100-meter race is the most popular event at the Olympics. More »

Nerves are required to repair the injured heart

Cardiovascular diseases (CVD), such as heart attack, are responsible for approximately 18 million deaths each year, which accounts More »

Can the developmental synchrony be affected by the mothers?

Biological synchrony is a ubiquitous yet highly diverse phenomenon, with examples as wide-ranging as More »

Regulation of mediator’s expression and chemotaxis in mast cells

The increasing prevalence of inflammatory diseases worldwide underlines the importance to study the molecular mechanisms leading to these disorders More »

 

A highly flexible and stretchable energy storage device

With rapid development of portable and wearable electronics, highly flexible and stretchable energy conversion and/or storage devices are required to be used as power sources. As one of the most important energy storage devices, supercapacitors (also called

Lessons from a small outbreak of poliomyelitis

The campaign to eradicate poliomyelitis, a paralytic viral neuroinfection, launched by the World Health Organization (WHO) in 1988, resulted in the drop of the disease incidence from several hundred thousands cases per year to less than one

IL-1 Receptor 8: a novel player in immunothrombosis

In addition to be a key component of blood hemostasis and coagulation, platelets have recently been implicated in thrombotic events associated with immune dysfunctions or inflammation. Platelets participate to innate immune responses and inflammation by releasing a

Multitasking in navigation in desert ants: combining multiple strategies

The highly social ants live in nests, and all their foragers must navigate their way home after finding food. Not surprisingly then, these small-brained travelers display proficient navigational prowess. Much studied are desert ants. They keep track

Using Rh immune globulin in pregnancy to prevent Rh disease

In addition to the ABO type, Rh(D) is also a major antigen, an antibody-generating protein, on the red blood cell (RBC) surface. An Rh(D)-negative person, one who does not have the Rh(D) antigen, can form anti-D antibodies

Male infertility and dental health status: the missing link?

More than 48.5 million couples worldwide are unable to conceive, and at least 40-50% of the cases are associated with male factor infertility (MFI), affecting approximately 31 million men worldwide. MFI is defined as alterations in sperm

Identification of new medicines for novel pathogen protein kinases with substrate-dependent assays

Protein kinases (PKs) are enzymes that transfer a phosphate group, a process called phosphorylation, from the ATP to another protein, which acts as a phosphoacceptor (Fig. 1). Phosphorylation of proteins regulate their activity, and these reactions are

A new hypothesis of autoimmune diseases: stress and the nucleolus

Autoimmune diseases (AIDs) have complicated pathologies influenced by genetic, epigenetic and environmental factors. Mechanisms of AIDs remain mysteries but numerous hypotheses have been proposed. Several hypotheses are discussed to present their unique explanations and to demonstrate that

MicroRNAs identify high-risk colon cancer patients

Choosing the optimal anticancer treatment for each patient requires proper disease staging. Staging is usually assessed according to the TNM system: tumour size (T), number of nearby lymph nodes affected (N), and metastasis, or spread to other

Perpendicular-plane configuration to prevent backward electron transfer

In organic chemistry, the outcomes of thermal and photochemical reactions are different. Reactions that do not proceed even at 200 °C proceed photochemically below room temperature, e.g., photosynthesis, the conversion of light (solar) energy to chemical energy

Reading “don’t cut the bread” triggers motor inhibition in the brain

All languages have negation markers, which allow the speakers to deny something, for instance the presence of an object (there is not bread), a feature (John is not cleaver), an action (you do not play piano), and

Curiosity and flexibility help birds to master rapid environmental change

Birds are one of the most mobile organisms on earth due to their ability to fly. This allows them to use areas far apart for breeding and non-breeding to exploit the best conditions throughout the year. For

Safety of iron oxide nanoparticles – a regulatory perspective

The ample domain of clinical as well as theranostic applications of super paramagnetic iron oxide nanoparticles demands the need for establishing a complete toxicological profile of these nano particles in a regulatory perspective prior to its intended

Activity Theory: quest for the unattainable and hope for the future

This paper addresses current problems of theoretical psychology focusing on future perspectives of the Activity Theory (AT). AT (Leontiev, etc.) is the most internationally known development of Russian psychology. AT is rooted in a long European philosophical

DNAJB6 – an early-stage scavenger of amyloidogenic peptides

A molecular chaperone has been discovered that binds to amyloidogenic peptides and delays onset of aggregation and neurodegeneration. Chaperone proteins, existing in the cells of all organisms, are helper proteins that serve to keep the proteins in

Can genetic changes in ApoM gene differentiate the patients at high risk of recurrent venous thrombosis?

Venous thrombosis (VT) is a major health problem worldwide and third most common type of cardiovascular disease. It causes more than half a million deaths every year in the European Union. An alarming proportion of VT patients