Brown bear habitat selection personality

You maybe think that only humans have personality? But don’t be a fool, animals can have personality too. More »

In vivo imaging of the lung inflammatory response to Pseudomonas aeruginosa

Chronic inflammation of the airways is a central component in lung diseases and is frequently associated with bacterial infections. More »

Sponge toxin kills lung and breast cancer cells in mice

Peloruside A is a potent toxin that was isolated from a New Zealand marine sponge. More »

An intracellular membrane system helps cells to divide

Cell duplication is the fundamental requirement for the development of multi-cellular organisms, a process that relies on two basic events More »

Can we stop dentist drilling too much on our caries tooth?

Dental caries is one of the most prevalent diseases worldwide. It is a result of hard tissue demineralization largely caused by acid produced by bacteria More »

Cooperative effects and co-crystallization in supramolecular diarylethene self-assembled monolayers

The current “top down” strategy that aims to miniaturize silicon based electronic components will eventually reach a limit. More »

 

Throwing a wrench into the hepatitis C replication machine

PatrickLWintrode-t

As an essential step in its replication cycle, the human hepatitis C virus (HCV) must make a copy of its RNA genome. The major player in this process is the NS5B polymerase, a molecular machine which uses

Vaccine research on Africa’s cattle-killing East Coast fever: A short (somewhat potted but handsomely illustrated) history

Tremendous research progress has been made over the last ten years to better control the deadly African disease of cattle known as East Coast fever. This disease is caused by a single-celled organism, Theileria parva, which is carried

Influence of DAOA and RGS4 genes on the risk for psychotic disorders

JordiSolerGarcia-t

Schizophrenia-spectrum disorders (SSD), including schizophrenia and other psychosis related conditions, affect about 3.5% of the population worldwide. Although there are quantitative differences, similar clinical and cognitive characteristics can be present across all the diagnoses of the spectrum.

Regular physical activity helps with the regulation of appetite and control of food intake

Relationship between standardised energy intake and physical activity level. Black line represents the mean of the z-scores. Red arrow indicates that decreasing physical activity level leads to an overconsumption of food more than requirements, whereas the green arrow indicates that increasing physical activity level leads to an increase in energy intake to maintain body weight.

It is widely known that regular physical activity is a vital component of a healthy lifestyle and weight management. Some studies suggest that regular physical activity is also beneficial for controlling appetite; however, the research has never

Assuming defeat, thwarting the feat: Defeatist beliefs, negative symptoms, and everyday functioning in people with schizophrenia

Imagine wanting to invite a friend for coffee. You might be thinking about what coffee shop to go to or what outfit to wear. But what if instead of planning the details of the coffee date you

ARTS (Aspiration-Retriever Technique for Stroke): A novel method for stroke treatment

FrancescoMassari-t

Ischemic stroke is not only one of the worldwide leading causes of disability and mortality but is also a significant burden on health systems. Actually the standard treatment for the acute event is based on a clot

Long learning curve for surgeons operating on esophageal cancer

Esophageal cancer is the eighth most frequently diagnosed cancer worldwide and the sixth most common cause of cancer-related death. The curatively intended treatment usually includes extensive surgery with removal of most of the esophagus (food-pipe) and the

Astrocytes, friend or foe in the brain

SusanBarnett-t

Glia, the “support” cells of the nervous system, are vital to the production, maintenance, and repair of one of the greatest triumphs of vertebrate evolution: the myelin sheath. For nerves to receive and conduct signals, as wells

The experts’ perspectives on domains, definitions and measurements of health literacy in chronic disease management

Health literacy is defined as a person’s skills to navigate and access health information and understand and interpret the information to make informed decisions about their health. Understanding what health literacy is and the impact it has

Evaluating the effectiveness of marine debris policies at a local level

LaurenBlickley-t

Slow to break down and nearly indestructible, plastics can last persist in the environment for thousands of years. Even more astounding is the amount of plastic that annually ends up in our ocean – an estimated 8

Do individuals with hearing loss change their driving habits over time?

Driving helps us carry out our everyday activities, stay socially connected, and maintain our independence and well-being as we age.   However, age-related cognitive and sensory changes may negatively impact an individual’s ability to drive.  The best predictor

Laser tool magnifies bacterial genotypic alteration as a colony phenotype

AtulKSingh-t

Gene manipulation tools are routinely used to create genetically engineered bacteria to understand the function of a gene or its role in pathogenesis in case of an infective microbe. Genetic engineering and manipulation of genes have been

Evaluation of a Farm-to-Preschool and Families program

ElenaCarbone-t

Despite recent decreases among preschool-aged children, child obesity is still an important public health concern. Community-based programs that focus on increasing fruit and vegetable intake is one way to address this issue. Although there is a strong

Artilysin®s as a novel enzyme-based approach to kill drug-resistant bacteria

In recent years world leading health care authorities have warned the global community about the threat of antimicrobial resistance. We risk being cast back into the dark ages when minor infections and injuries were often lethal. However,

Antioxidant potential: curcumin vs curcumin glucuronide metabolites

AmbarKChoudhury-t

Turmeric, the household spice, contains a major colouring pigment known as curcumin, together with other colouring agents (i.e. curcuminoids). Curcumin is known to exhibit potential antioxidant activity with therapeutic potential as anti-cancer, anti-inflammatory, anti-arthritic, anti-diabetic agent and

Microfluidic “plaque-on-a-chip” with pH new imaging concept probes individual factors in tooth decay

JesseGreener-t

Your teeth are covered in biofilm called plaque. This biomaterial consists of bacteria in a protective matrix of proteins, polysaccharides and other long organic molecules. When you eat or drink, bacterial respiration and other metabolic processes convert