Mapping red nucleus connections in humans by using dMRI and tractography

Mapping red nucleus connections in humans by using dMRI and tractography

Human brain is an enormous and complex network. Central to current scenario on brain networks is the concept of the connectome More »

Curiosity and flexibility help birds to master rapid environmental change

Curiosity and flexibility help birds to master rapid environmental change

Birds are one of the most mobile organisms on earth due to their ability to fly. This allows them to use areas far apart for breeding and non-breeding More »

Virus chainmail: protective and porous metal-organic framework grown on a virus

Virus chainmail: protective and porous metal-organic framework grown on a virus

Biomineralization describes a process of programmable accumulation, concentration, and construction of inorganic ions regulated by organisms to form both amorphous More »

Species are always important

Species are always important

This review is based on the premise that all species are important to life on earth even if the exact role or value of a species has not been formally documented More »

 

Large animal models for osteochondral regeneration

Comparison of common currently used large animal models

Due to the lacking of a blood supply and the low cellular density of articular cartilage, this hard tissue has a limited healing capacity. Therefore, focal traumatic events causing cartilage defects rarely resolve spontaneously or are usually

Thermo- and soluto-capillarity: Passive and active drops as micro-fluidic carriers or reactors

Why study drop (or bubble) motions? Drops can be seen free, hanging, suspended in air, sessile, aggregating, coalescing, disintegrating/splitting or spreading in nature, in engineering processing or at home. Think about dew, fogs with drops of diameters

Frac-seq uncovers widespread RNA dysregulation in severe asthma

Frac-seq uncovers widespread RNA

Asthma is a common chronic disease consisting of constriction and inflammation of the airways as well as structural changes known as remodelling (Fig. 1). 5-10% of patients have severe asthma, whereby symptoms persist despite regular and correct

Increased time incongruence between imagined and actual walking in frail older adults

Comparison of constant error in frail older and young adults

Mental chronometry is commonly used to evaluate motor imagery ability. Mental chronometry measures imagined time required for movement. Smaller differences between imagined and actual times suggest higher motor imagery. Imagined and actual times for movement tend to

Talking about childhood music: A twin study

Talking about childhood music

To what extent do childhood experiences of music practice influence thinking about music later in life? We could get an idea about this if we talk about childhood music memories while physiological recordings are made concomitantly. If we observe that there are clear

Pursuit of a genuine effect of acupuncture: development of placebo acupuncture needles

Acupuncture needles for double blinding

Acupuncture has been used to treat a wide range of health conditions. The efficacy of acupuncture has not conclusively been established because only randomized control trials using single-blind needles have been reported. Single blinding is problematic because

How do we navigate a world with deep temporal structure?

simulated behavioural responses during reading

Navigating our dynamic but structured environment is an essential part of everyday life. For example, when reading this sentence, we pre-empt the context and purpose based on our internal representation of the world and actively sample it

A DNA repair gene, OGG1, polymorphism affects relapse risk of acute myeloid leukemia

A DNA repair gene, OGG1, polymorphism affects relapse risk of acute myeloid leukemia

Approximately 80% of acute myeloid leukemia (AML) patients can achieve complete remission, but around half of them relapse within five years. Defining the mechanism of relapse is essential to improve the prognosis of AML. Recently, a clonal

How to stain E-selectin ligands in tumor tissue

How to stain E-selectin ligands in tumor tissue

Cancer affects millions of people around the world. Nowadays they have more chances to survive, but still, the most frightful scenario are metastases. Few patients with metastases survive, and there is an unmet clinical need for new

Milk and beef: Do production enhancing hormones pose a health risk?

After World War II, a sharp increase in demand for beef and dairy products, coupled with a burgeoning veterinary pharmaceutical industry, led to a number of changes in animal husbandry, including a reliance upon exogenous hormones to

Heat, diet and lifestyles control longevity in animals and man

Heat, Diet and Lifestyles control Longevity in Animals and Man

The inactivation of the heat shock gene called Sirtuin 1 (Sirt 1) is associated with many chronic diseases such as diabetes, non alcoholic fatty liver disease (NAFLD), cardiovascular disease and neurodegenerative diseases. Factors such as body temperature

Control of doping in racing pigeons

Pigeon racing is considered a popular sport in several countries such as Belgium, England, Netherlands, Portugal, Japan, Taiwan and South Africa. In all these countries, pigeon racing is a federated sport and racings take place on a

Chemical toxicity study of some Algerian medicinal plants

About 65 to 80% of the world’s population use traditional medicine for their primary health WHO according to the WHO report. However, the use of herbal medicines has come under scrutiny due to their perceived long-term toxicity

Molecular targeted therapy in alveolar soft part sarcoma

Molecular Targeted Therapy in Alveolar Soft Part Sarcoma

Alveolar soft part sarcoma is a malignant and rare tumor that includes about 1% of all STS (soft tissue sarcoma), and usually occurs in adolescents and young adults. This type of cancer has tendency toward distant metastasis

Can tree rings be used as pollution bioindicator archives to reconstruct past environments?

Heavy metal contents in wound and bark

Trace heavy metal (HM) pollution over time and space is becoming a growing global problem, as many studies have confirmed that human activities have dramatically increased natural concentrations of metal pollutants in the last century. HM are

Development of the Japanese version of the Kinesthetic and Visual Imagery Questionnaire (KVIQ)

Internal consistency of the KVIQ-20/KVIQ-10

Motor imagery is commonly defined as the mental simulation of one’s own performance without any associated overt movement (Jeannerod M, et al. Behav Brain Sci. 1994). Previous studies have suggested that motor imagery increases motor skill acquisition

Rethinking drugs’ development in acute heart failure?

The ten drugs developed in AHF during the last two decades

Acute heart failure (AHF) affects 1-2% of adults in developed countries. It strikes mainly people above the age 60, peeking in those older than 85 (prevalence ~ 17.4%). AHF is a life threatening medical event, with gradual

Strategies to enhance antioxidant potential and biosynthesis of essential oils in Ajuga bracteosa

Strategies to enhance antioxidant potential

Essential oils are the plant-derived natural products and are called “essential” due to the essence of the distinctive fragrance they contain, specific to the fragrance of the respective plant from which they are derived. A large portion

Evolution of the art and science of kidney transplantation in HIV positive patients

Evolution of the Art and Science of Kidney Transplantation in HIV

Once considered prohibitive, kidney transplantation in HIV (+) recipients is achieving outcomes similar to comparable recipients without HIV. These successes are possible because of incremental improvements in care that resulted from lessons learned from the last two

Early – life seizures: alarm bell for often severe clinical outcome

EEG during sleep showing Burst-suppression pattern in 3 months infant with Ohtahara syndrome.

Early life seizures (ELS) are a not uncommon clinical manifestations in infancy affecting from 1.8 to 3.5/1000 live birth. In infancy with rare exception of seizures typically benign  which include the Benign Familiar Neonatal Epilepsy (BFNE), Febrile