Daily Archives: November 16, 2015

Over-expression of TRX2 reduces p53-mediated cell death in yeast

The p53 gene is a human tumor suppressor which is involved in cell cycle regulation. It has an efficient ability to inhibit cell proliferation, by both blocking cell cycle progression and promoting apoptotic cell death in order

The future of Laron syndrome

Laron syndrome (LS) first described 50 years ago in 1966 is with few exceptions a genetic form of severe short stature, found in the majority of instances in patients originating from the Mediterranean, Middle East and South Asian

One for two – one medicine against two diseases

Superficial fungal skin infections belong to the most common infections worldwide. They affect more than 20 – 25 % of the world’s population with an increasing trend due to an increasing life expectancy and decreasing immunity of

An internal granuloma investigated by light and scanning electron microscopy

Caries and Periodontitis are not the only reasons why patients may suffer from problems with their teeth. There are far less frequent occuring phenomena causing dental treatment need, which however are of research interest in respect to

How cancer cells resist the action of microtubule-targeting chemotherapeutic drugs? A study of β-tubulin mutations

Microtubules (MTs) are essential structural components of cells. They are made up of polymers of protein subunits of α,β-tubulin and are highly dynamic, undergoing rapid phases of assembly and disassembly. The dynamic behavior of MTs is essential

Prostate cancer: prognostic impact of adenosine-generating CD73

Traditionally, most cancers were treated with surgery, radiotherapy or chemotherapy (or a combination of these options). Using the immune system to fight cancer has long been the objective of many researchers, but convincing success in the clinic

Improving the mathematical estimation of the epidemic threshold on networks

Infectious diseases spreading via person-to-person contacts, such as plague, flu, and Ebora, have threatened humanity since the beginning of the recorded history. Societies have long been using the power of sciences to understand and mitigate the impacts

A Tat ménage a trois – when it comes to Tat secretion two Tat’s are essential, but the third one makes it that much better

The membrane is the cellular barrier that keeps the inside of a cell separate from the outside, but in order to survive molecules and proteins do need to cross this barrier. Water and small molecules can do

Post-surgery early aerobic exercise: reduces lung complications and hospital stay

Lung related complications like infections and clots are common after complex abdominal surgery. These have a negative effect on the patient’s recovery, can prolong hospital stay and can even lead to death. We performed a study to

The thinner, the glassier

Polymers are a key component of our technologies. The diversity of uses and forms of these inexpensive materials is impressive: polymers are present in almost all the aspect of everyday life. Polymers are also intensively studied at