Monthly Archives: March 2017

Measuring motivation in Parkinson’s disease through the eyes response to money

Apathy or a lack of motivation is a disabling condition making patients feel that they “just can’t be bothered to do things”. Apathy is very common in Parkinson’s disease, affecting up to 70% of patients and causing

Do children with Autism Spectrum Disorder understand the representational meaning of the eye gaze?

Gaze following is crucial for human social cognition, this ability develops from a low-level perceptual mechanism to a representational one. In typical development, between 6 and 12 months, infants perceive the gaze as a directional cue that

Candidate gene analysis of osteochondrosis in Spanish Purebred horses

Equine osteochondrosis (OC) is a frequent developmental orthopaedic disease (DOD) with high economic impact on the equine industry. The multifactorial origin behind its aetiology, including genetic, vascular or biomechanical influences, as well as other environmental factors such

Ankylosing spondylitis: what you should know about spinal fractures

The aim of this review article was to provide the required clinical knowledge that radiologists need to know and the relevant radiological semiotics that clinicians require in diagnosing clinically significant injuries to the ankylosed spine. Ankylosing spondylitis

The positive resting membrane potential of non-excitable fibrocytes in the mammalian cochlea

It is schoolbook knowledge that both excitable and non-excitable cells are stably hyperpolarized at -25 mV to -80 mV in the resting state in vivo and in vitro. This negative resting membrane potential (RMP), a fundamental cell

Too little sun-exposure in summer?

It is well known that UV rays are responsible for DNA damage in exposed cells: because of that, they are considered carcinogens for skin cells. In the last decades, frequent worldwide campaigns have advised people to avoid

Why is anxiety more common in women? Investigating sex differences in threat and safety learning

Anxiety-related disorders like post-traumatic stress disorder (PTSD) are up to twice as common in women as in men but the reasons behind this remain unclear. People with PTSD often experience negative emotions like fear when reminded of

Repelling water and dirt: superhydrophobic biological surfaces and biomimetic innovations

Life evolved over the last 3.5 billion years: a continuous process of mutation and selection – or trial and error. Today we know of some 1.8 million different species – but assessments indicate the existence of over

Cerebellar and brainstem malformations

The development of the cerebellum and brainstem is a highly complex process that involves a large number of genes. Mutations in these genes may cause an abnormal development of the cerebellum and brainstem and result in several

Trends in population characteristics, 30-day outcomes and one-year survival in patients treated with TAVI

Since the first-in-man transcatheter aortic valve implantation (TAVI) performed in our center in 2002, this technique has been increasingly accepted by the medical community as a viable and established option in patients with severe aortic stenosis (AS)

Medical students’ communication is trainable

A good physician-patient-relationship is essential for the patient’s health. Accordingly, the therapeutic relationship can influence the success of the therapy with a variance of 30%. A well-structured, patient-centred medical history taking enables an earlier and more accurate

New chemistry of aryl(2,2,2-trifluoroethyl)iodonium triflates

Fluorine-containing organic compounds have found wide applications in the areas of chemistry, biology, and materials science over the past several decades. Since only a few naturally-occurring organofluorides have been discovered, fluorinated organic compounds including CF3CH2-substituted compounds have

Easy assessment of the vascular autonomic function

Blood vessels change their diameter to keep a stable blood flow. The diameter of the peripheral arteries is determined by contraction or relaxation of the vascular smooth muscle, by endothelium-dependent and autonomic nerve-dependent mechanisms. Vascular endothelial cells

What about noninvasive prenatal testing (NIPT) from ‘cell-free fetal DNA’ (cffDNA)?

To know anything about the unborn human life was pure science fiction until the end of the 1950s. However today, prenatal diagnostics is routine, and many different approaches are available to check out the health of a

A new enhanced antibiotic treatment for early and late syphilis

Despite an effective treatment for syphilis is available since the penicillin introduction in the mid-20th century, this disease is still a global health concern with over 12 million new cases occurring each year worldwide. Recently, we have

Immobilization of bilirubin oxidase on graphene oxide for oxygen reduction – when the charge matters

In recent years knowledge from nanotechnology , biotechnology and electrochemistry helped to develop extremely interesting devices – biofuel cells. In such devices , many different biomolecules have been employed for biologically catalyzed energy harvesting from energy rich