Daily Archives: June 16, 2017

Unraveling multiple checkpoints for accurate selection of initiator tRNA on ribosomes for translation initiation

Ribosomes comprise a large (50S) and a small (30S) subunits. To begin (initiate) protein synthesis, the two subunits associate on an mRNA (70S). Organisms possess two classes of tRNAs, the initiators (i-tRNA) and the elongators. The i-tRNA

Octreotide – a promising fight against chronic intestinal pseudo-obstruction

Chronic intestinal pseudo-obstruction (CIPO) is a rare disorder that affects the intestinal tract of children and adults. It is a chronic and devastating disease that has significant morbidity and mortality. CIPO is characterized by severe and disabling