Daily Archives: February 5, 2019

Do you want a specific signal? Go local! Imaging our way to targeted therapy

Cyclic adenosine monophosphate (cAMP) is a ubiquitous intracellular second messenger, a small molecule that conveys the information carried by hormones, neurotransmitters and other extracellular stimuli to the intracellular environment. cAMP is generated at the plasma membrane when

Are there differences in structural and mechanical properties of R15, R16 and R17 spectrin domains?

Spectrin is a cytoskeletal protein that plays an important role in maintenance of plasma membrane integrity and cytoskeletal structure. It determines the strength, mechanical stability and capacity for deformation of cells. Spectrin forms a reverse parallel heterodimer