Category Archives: Research

Fiber refractometry revisited

Response of three sensors across three different RI Zones.

The refractive index (RI) n of a substance is generally defined as the ratio of the speed of an electromagnetic wave in vacuum c to its velocity in that substance v, or n = c/v. Refractive index

Magnetic NPs for automatic speciation analysis of inorganic arsenic in environmental water samples

Magnetic NPs for automatic speciation analysis

Arsenic is a ubiquitous element in the environment originated from natural sources as well as human activities. This element has been identified as a public health problem because it has serious toxic effects even at low exposure

Sliding esophagoplasty. Can esophagectomy be avoided in esophageal obstruction due to huge thoracic aortic aneurysm?

Thoracic aortic aneurysm is a serious vascular disease which usually requires surgical aortic graft replacement. In recent years, endovascular stent placement proved a mini-invasive alternative to be used safely in properly selected instances particularly in subjects considered

Biologically active chemicals in yellow-cedar protect tree tissues and possibly human health

Nootkatone, a biologically active oxygenated sesquiterpene in yellow-cedar heartwood

Yellow-cedar trees, also known as Callitropsis nootkatensis, can live for hundreds of years because they have has few insect or pathogen pests. Periodic studies over the last century have examined extractable chemicals in their tissues and discovered

Is the gravimetric water content true? NIR spectroscopy gives an answer for polymers and composites

The more water is inside the polymer, the more intense the peak.

A common way to measure water content is by weighting the polymer or a composite sample, using a gravimetric method. This method often overlooks that there is already some water inside the initial (mistakenly called “dry”) material.

Non-invasive prenatal testing – safer or simply more profitable?

Map of Europe

Non-invasive prenatal testing (NIPT) is growing more and more popularand is advertised worldwide by dozens of companies as a safer alternative to invasive testing. In most countries it is paid for privately by the patient. But its

Behind the journey to spawn of European eels: expression and role of adrenergic receptors during silvering

Adrenergic receptors

Eels make an astonishing journey to spawn, migrating from Europe to the Sargasso Sea, near Bermuda, and back again. After spawning, larvae are transported by the Gulf Stream to the continental shelf of Europe and North Africa,

Climate change and the unfeasibility of United Nations Sustainable Development Goals

Climate change and the unfeasibility

With recent upward trends in global temperatures and sea levels, many countries are experiencing higher rates of evapotranspiration, groundwater depletion, water salinity, and loss of habitats.  Moreover, increases in living standards entail higher consumption of animal products

Inhibitors of intracellular enzymes for treatment of multiple sclerosis

The protein kinase inhibitor imatinib

Lymphocytes are white blood cells that are central in the immune response to foreign microorganisms. Like all cells, lymphocytes have a membrane, a lipid bilayer, that envelops the content of the cell. Proteins attached to the cell

Finding the beta-beta residue pairing for protein structure prediction

protein structure prediction

Prediction of the tertiary structure of proteins from their amino acid sequences is of great importance and of urgent demand in structural bioinformatics and biophysics, especially considering the increasing gap between the numbers of sequences and structures

Repetitive DNA in the ABCA7 gene influences Alzheimer’s disease

Repetitive DNA in the ABCA7 gene influences Alzheimer’s disease

Dementia, which is characterized by decline of memory or other cognitive traits to the extent that a person’s daily functioning is affected, is one of the most important global health challenges of our time. Approximately 50 million

Objectivity applied to embodied subjects

Objectivity is a contested concept, especially when applied to human beings. Subjectivity is pervasive in human life, and personal passions and feelings are spices of daily existence. We argue that a cognitive concept of objectivity is appropriate

A new biomarker for Triple negative breast cancer MCP-1 drives cancer invasiveness and metastasis

Model of MCP-1 action in breast cancer cells

Breast Cancer is the second leading cause of mortality in women in the United States. Breast cancer arise in the ducts of the mammary glands that produces milk in a lactating breast. Breast cancers usually express various

Can historians work with environmental scientists? New insights for addressing climate change from interdisciplinary research

Data sources and characteristics

How can we uncover how past societies responded to and accommodated changes in their physical environment?  It is an important question, because climate change as well as natural events such as droughts, earthquakes and volcanic eruptions could

Advanced plasmonics: Self-assembly brings order

How to make perfectly ordered membrane without ordering

Nanoporous self-organized membranes are complex, sophisticatedly fabricated, hierarchical nanostructures which combine several unique properties such as very developed surface area and long pores through the whole free-standing or surface-bond films of several micrometers to several hundred micrometres

miR-146 and miR-155, two key modulators of the immune response and of the oncogenic transformation

miR-146 and miR-155, two key modulators of the immune response and of the oncogenic transformation

Micro-RNA (miRNAs or miRs) are small noncoding RNAs that negatively regulate protein coding gene transcripts and exert an important role in the control of gene expression. miRs are deregulated in many tumors and play an active role

Bone marrow chilling could warm the body

Bone marrow chilling could warm the body

In order to keep warm during cold exposure, heat production must be increased. This can be achieved through non-shivering and shivering thermogenesis. The main tissue involved in non-shivering thermogenesis is brown adipose tissue (BAT) which is located

Crossing borders to accelerate diagnosis of neurodegenerative diseases

Steps in biomarker development process

Neurodegenerative diseases of the Central Nervous System are affecting 50 million people worldwide. The forecast is that these numbers will steeply increase due to the aging population. These diseases are difficult to diagnose, due to a substantial

Parkinson disease: a tale of three neurotransmitters

The progressive loss of dopaminergic innervation of the basal ganglia, in particular of the dorsal striatum (putamen) is responsible for the motor signs of Parkinson disease such as bradykinesia, rigidity and loss of postural reflexes. Present therapies

No-bonding reactivity of Helium under pressure

The 1D model of He insertion into AB and A2B compounds

Noble gas (NG) elements have been thought historically to be chemically inert. Nevertheless, already in 1930, Pauling predicted that Xenon could react with other elements. Thirty years later, Bartlett synthetized the first Xe compound, Xe+[PtF6]–. High pressure