Category Archives: Research

Malaria and hypertension-a new hypothesis in clinical medicine

Research from University College Cork, Ireland and New York University School of Medicine, USA has shown a credible link to the high rate of hypertension, stroke, and myocardial infarction amongst Africans and Afro-Americans, and a genetic defence

Applying nanopharmacology to obstetrics: A novel targeted drug delivery system for the uterus

Pregnancy is a dangerous period for both the mother and foetus. Being born too early (preterm birth) is the leading cause of death and disease in children <5 years of age, while insufficient uterine contractions during or

Unravelling the mystery of rampant species formation on volcanic islands

How do new species of plants and animals arise? And why do clusters of divergent endemic species evolve so rapidly on remote oceanic archipelagoes such as the Hawaiian and Galápagos Islands? These questions have intrigued biologists since

Cornification derived from keratinization through the addition of new epidermal proteins to keratins

Differentiation of epidermal cells in vertebrates takes place by high production of structural proteins termed keratins that belong to cytoskeletal proteins indicated as Intermediate Filaments (α – keratins). The epidermis of vertebrates is a multilayered epithelium that

Fish is an important source of micronutrients to fight the micronutrient deficiency, otherwise known as the ‘hidden hunger’

Macronutrients are the major nutrients such as carbohydrate, protein and fats, required in large quantities which provide the bulk of the energy whereas micronutrients (minerals and vitamins) are needed in small amounts in the body; however, are

Avoiding the dilemma between too much alcohol and too much volatile acidity in wine

Over the past 50 years, the average global temperature has increased at the fastest rate in recorded history, thus affecting the production of many crops, including wine grapes. Indeed, global warming uncouples technological and phenolic maturity of

New ligand for preconcentration of lanthanides from environmental samples prior to ICP-MS analysis

Lanthanides are a group of chemical elements (La-Lu) with very similar behavior. Due to their unique properties they find application in many high-tech fields as computers, liquid crystal displays (LCDs), clinical MRI, lasers etc. The increased usage

Technical revolution of D-amino acid profiling

Amino acids are essential and ubiquitous compounds for living organisms on Earth. Proteinogenic amino acids (except for glycine) have chiral carbon, and those enantiomers (L-form and D-form) exist (Fig. 1). L-forms predominantly exist in nature, therefore researches

Hospital readmission after head and neck microvascular reconstruction

Unplanned readmissions are associated with decreased healthcare quality and increased costs. This nationwide study examines causes for unplanned readmission among head and neck cancer patients undergoing immediate microsurgical reconstruction. Patients undergoing head and neck tumor resection with

The role of monocytes in ANCA-associated vasculitides

The anti – neutrophil cytoplasm antibody (ANCA) – associated vasculitides (AAV) include granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA), and eosinophilic granulomatosis with polyangiitis (EGPA). These rare systemic autoimmune diseases affect small and medium – sized blood vessels, and are characterized by necrotizing vasculitis,

Diagnosing Fragile X syndrome by DNA methylation array

Fragile X syndrome (FXS) is the most common genetic condition which causes a range of developmental problems and intellectual disability in males. It is caused by a mutation in the fragile X mental retardation gene (FMR1), which

What are the psychological drivers of religious history?

When the Buddha became “Enlightened” he realised that what is important about human beings is their ethical intentions.  These are the grounds of karma in Buddhism.  And he realised too that everything we call a “thing” is

“Contagious and bad”. The stigma of Mycobacterial infections

Two diseases caused by mycobacteria, Tuberculosis and Leprosy, not only are they quintessential in the history of infectious diseases and humanity, but have survived the passing of the centuries still affecting millions around the world. Being present

Application of ultrasensitive electrochemical biosensors for specific analysis of a glycan on a prostate-specific antigen

Prostate cancer (PCa) is the second most common cancer worldwide, accounting for more than 1.1 million cases in 2012.  The statistics says, that about 1 man in 7 will be diagnosed with PCa during his lifetime with

A figure-of-eight molecule twists the red light

Development of fluorophores for CPL, circularly polarized luminescence, has attracted much attention. CPL has large potential toward future applications such as 3D displays and biosensing.  Major challenges in creating good CPL fluorophores are; 1) large anisotropic dissymmetric

New types of functional pasta enriched with lyophilized tomato or wheat bran antioxidant extracts

The increasing demand for healthy foods has encouraged food companies to direct new research and development activities towards products providing, beyond basic nutritional functions, beneficial effects for health and/or reducing the risk of chronic diseases, i. e.