Category Archives: Research

New psychoactive substances and drugs of abuse inhibit neuronal activity

New psychoactive substances (NPS), also known as ‘legal highs’, ‘bath salts’ or ‘research chemicals’, appeared on the drug market around a decade ago. Even though they account for only a small proportion of the market, NPS encompass

SERS substrates by vacuum-free dealloying of Au-based metallic glass ribbons

Plasmonics has become an important photonic device due to the advancement of fabrication technologies in recent decades. It has many applications including solar cells, nonlinear optics, metamaterials, photocatalysts, and surface-enhanced Raman spectroscopy (SERS), etc. Among those, SERS

Calcium ion by replacing magnesium ion unravels an unexpected role for the mitochondrial F1FO-ATPase

The F1FO-ATPase/synthase is universally known as a complex enzyme machinery which, embedded by the FO portion in the inner mitochondrial membrane and the catalytic F1 sector protruding in the matrix, matches the transmembrane proton flux which occurs

Costly reputation maintenance behavior is a building block of human cooperation

Reputation plays a crucial role in human cooperation. This is because people tend to cooperate with someone with a good reputation. For example, if Anne knows that Bob helped Cathy before, and Bob is now in need,

Better implants with stem cells

Prosthetic implants are used day-to-day to treat edentulous people and patients in need of skeletal reconstructions. The history of prosthetic dental implants dates back thousands of years, with the early civilizations using seashells and stones to replace

Oriented attachment determines a shape of nanoparticles in gas phase

Until two decades ago, the process of crystallization from a supersaturated solution was assumed to proceed exclusively by molecule-by-molecule addition. However, some recent pioneering theoretical and experimental studies have revealed that crystals can grow by some other,

Acute ischemic stroke: An urgent call for help and funding!

In humans, acute ischemic stroke is the primarily result of a blood-clot that moves toward the brain and blocks one or more important blood vessels that supply blood, oxygen, and nutrients to brain tissue (Fig. 1), causing

Genital gender-affirming surgery: a history from the shadows to the forefront

Gender dysphoria is characterized by a discrepancy between an individual’s gender at birth and the gender with which they identify themselves. Gender-affirming surgery encompasses a variety of procedures that aim to alleviate gender dysphoria. These are broadly

Open storage of sub-soil river water leads to significant change in water quality

Reservoirs and dams are created for catering to the need of agriculture, industries, domestic etc as a continuous reliable source of water. Among other uses, power plant (PP) cooling water system (CWS) needs reliable and continuous supply

How the mitochondrial F1FO-ATPase can be chemically switched on/off and serve as drug target

The mitochondrial F1FO-ATPase is well known to play the main role in synthesizing most of ATP, thus providing energy to living cells under aerobic conditions. However the enzyme complex can also  work in reverse and split ATP

Early sepsis does not stimulate reactive oxygen species production and does not reduce cardiac function despite an increased inflammation status

Sepsis is due to bacterial infection. If it is sustained for several days, it can trigger severe abnormalities of cardiac function which leads to death in 50% of cases. This probably occurs through activation of toll-like receptors

Varity of phase separation patterns induced by a propagating trigger

A pattern is formed when a phase separation in two component mixtures occurs. A bicontinuous network pattern is formed when the concentration of the two phases are symmetry to the phase separation line. Meanwhile, when there is

Less may be more in catheter ablation of persistent atrial fibrillation

Atrial fibrillation (AF) is the most prevalent heart rhythm disorder worldwide; at present, it affects more than 33 million subjects globally and it is expected that its prevalence will double over the next 50 years. The condition

Astroglial magnetic fields and cortical neuronal coupling

In recent years, it has been demonstrated an increasing role of astrocytes in information processing and cognitive functions, which depends on the close relationship between neurons and astrocytes into the cerebral cortex. The mammalian cerebral cortex is

Pubic hair grooming and public health. A key role for the doctor in counselling his patients?

We think there’s a role of counselling for health practitioners related to the practice of hair grooming. Despite the lack of controlled studies, it could be dangerous to deny the possibility of infectious risks related with this