Tag Archives: AMPK

Cellular stress and AMPK links metformin and jumping genes with the creation of human life

The evolution of the human genome has been facilitated to a great extent by the activity of transposable elements (TEs), also known as “jumping genes”. As the name implies, TEs are DNA sequences capable of moving or

Metformin and AMPK link cancer stem cell elimination with the potential eradication of HIV

Cancer stem cells (CSCs) are cancer cells that exhibit several stem cell-like qualities that are characteristic of embryonic or adult stem cells, including self-renewal, differentiation, and the ability to initiate tumorigenesis. CSCs, similar to adult stem cells

Oocyte activation and latent HIV-1 reactivation: AMPK links the creation of all human life and the potential eradication of HIV-1

In an active area of research known as HIV-1 cure research, the purposeful reactivation of latent/dormant HIV-1 in memory T cells, which induces death of the infected cell or alerts the immune system to the presence of

AMPK: How can we amp it up to fight disease?

The high prevalence of obesity, insulin resistance, type 2 diabetes and cardiovascular disease has made it clear that we need a better understanding of how our bodies store and use energy when we overload them with excess

AMPK, an energy consumption supervisor, regulates hedgehog and may be a cancer therapeutic target

A cell can be thought of as a factory with many machines controlling different processes. Cell growth is the process by which a cell divides and multiplies. It is a highly energy-consuming process. Therefore, supervisors are needed