Tag Archives: biofilm

Host factors, the “Simon Says” for microbial biofilms

Microbes change their behavior, i.e., phenotype, in response to environmental clues. Since microbes, e.g. normal flora and pathogens evolved with their respective hosts, being able to recognize host-derived chemical signals provides a distinctive advantage. This is particularly

Microfluidic “plaque-on-a-chip” with pH new imaging concept probes individual factors in tooth decay

Your teeth are covered in biofilm called plaque. This biomaterial consists of bacteria in a protective matrix of proteins, polysaccharides and other long organic molecules. When you eat or drink, bacterial respiration and other metabolic processes convert

Materials for tomorrow: right next to us!

The idea of an artificial device able to help human parts to regenerate or to replace entirely one of the body functions attracted the attention of research teams around the world. During recent years, a route of

Potassium in dental plaque, an old story with a new perspective

Dental plaque or biofilm is home to caries causing bacteria such as Streptococcus mutans. Interestingly, the fluid in the biofilm is like an aqueous reservoir of material shared between different species. Although the fluid content is derived

Flares and pirouettes: the different moves of spinning bacteria

Bacteria often form together on surfaces in dense communities, known as biofilms. These cause medical and industrial problems because this lifestyle increases their resistance to disease and other stresses, making them difficult to remove. We aim to

Protecting titanium implants from infection

Certain microorganisms are capable of growing in layers, forming biofilms on medical surfaces, like implants, heart valves, etc… Biofilm-associated infections on implants are responsible for 15-25 % of implant failures as biofilms are resistant to most of the

The matrix reloaded: how a self-produced extracellular matrix controls the development of multicellular microbial communities

In nature, many bacteria live in multicellular communities called biofilms. Biofilms offer their resident bacterial cells protection from environmental insults and assaults, and better attachment to hosts. For humans, they have medical and industrial costs, but also

Can bacteria resist a new antibacterial method?

Antibiotic resistance in bacteria is on the rise worldwide, making some previously-treatable infections incurable or even life-threatening. Thus there is a growing need for the discovery and development of new antibacterial methods of disinfection. Ideally these methods

Bacterial cross-talk with small molecules

Bacteria, the unicellular prokaryotic microorganisms are the first form of life to appear on earth that may be traced way back about 4 billion years ago. Bacteria exist in typically two life forms i.e planktonic or free-swimming

Filamentous bacteriophage organize bacterial biofilms into liquid crystals

At sites of chronic infection, bacteria form biofilms, clusters of bacteria encased within a slimy, polymer-rich coating called the matrix. Biofilms are of concern because bacteria within biofilms become tolerant not only to environmental stresses, but also

Hybrid moving bed biofilm reactor-membrane bioreactor system for micropollutant removal

In recent years, the frequent detection of micropollutants in the aquatic environment has raised growing concerns due to their detrimental effects on aquatic organisms and human health. Micropollutants, also termed emerging contaminants, consist of a wide variety

Fighting (for iron) to survive: therapeutic avenues for aspergillus fumigatus infections

Aspergillus fumigatus (Af), a common fungus, frequently infects the lungs of patients with compromised immune systems. Despite progress in developing anti-fungal agents, Af infections still cause a significant number of deaths, making new treatment options necessary to