Tag Archives: Biomarker
Cancer is a primary cause of human death with a global economic toll of around US$1.4 trillion each year. It is estimated that about 12 million people will yearly die of cancer by 2030. Conventional cancer therapies such
Thanks to the development of endocrine therapy, the mortality rate of estrogen receptor (ER)-positive breast cancer patients has been decreased drastically. In spite of the improvement, however, relapse and progression that are driven by different mechanisms are
Tongue squamous cell carcinoma (TSCC) is the most predominant form of oral cancer in developed countries with varying incidence in developing countries wherein diverse etiological factors such as chewing betel-quid comprising betel leaf, areca nut and slaked
World Biomarkers 2017 is organized around the theme: “A New Era of Diagnosis and Clinical Research”. World biomarkers, in the hands of clinical investigators, provide a dynamic and powerful approach to understanding the spectrum of diseases with
Abnormal structural changes measured on cortical surfaces are important biomarkers for Alzheimer’s disease (AD). In brain imaging research, landmark curves are usually delineated on cortical surfaces to represent significant sulcus and gyrus patterns. Landmark curves are widely
How did computers help us to find biomarkers for corticosteroid resistance in asthma through systems biology approach?
Asthma is a chronic disease that affects the lower airways, hampering the air movement in the lungs and the gas exchange. Asthma is characterized by bronchial inflammation that, particularly during an asthma attack, results in difficulty of
The most common form of adult liver cancer is hepatocellular carcinoma (HCC), which is the third-leading cause of cancer deaths worldwide. HCC arises from persistent liver inflammation related to hepatitis B or C infection, alcohol consumption, or
Duchenne muscular dystrophy (DMD) is an X-linked muscular disease, affecting boys in principle. It is caused by mutations in the gene coding for dystrophin, a membrane-related structural protein in skeletal and cardiac muscles. The lack of dystrophin
T cells are important players of the immune system, recognizing foreign or dangerous agents with their unique receptors. They defend the body from these agents either directly by killing or by recruiting or regulating other immune system
When it comes to treatment of brain diseases not affecting the motor-system, drug development has proven difficult, because the majority of tests of drug-effects in animal experiments rely on changes in the behavior of the treated subject.
In recent years we have seen an increased frequency of diagnosed prostate cancer (PCa) cases accompanied with an enhanced mortality worldwide. Symptoms of an early-stage PCa can be mild or even absent, thus there is an urgent
Schistosomiasis or bilharzia is a tropical disease caused by worms of the genus Schistosoma. Over 440 million people from 76 countries and territories are infected (Fig. 1). This water-based disease is considered the second most important parasitic
Aim of this study was to assess the potential of milk fatty acids (FA) as a diagnostic tool for hyperketonemia. Negative energy balance is a common phenomenon in the transition period in dairy cows. During this period,