Tag Archives: blood

Silencing a microRNA may keep the doctor away for diabetic wounds

Patients with diabetes are frequently afflicted with impaired wound healing that may progress into chronic, diabetic ulcers, often leading to complications including limb amputation with increased risk of morbidity and mortality. These ulcers occur not only in

Light enhances the blood glucose monitoring with naked eye

Enzymes play an important role in the body of a plant or animal. Natural enzymes have been extensively investigated and widely applied in industry because of their excellent properties, including high substrate specificity and catalytic efficiency. However,

Heart and blood pressure adverse effects of phenytoin

Phenytoin is an effective antiepileptic drug which is used for many years in the treatment of epileptic seizures. Whereas its oral form is used for the long-term treatment of epilepsy, the intravenous form – the injection into

Tapping neurotransmitters from neurons to investigate their involvement in brain function

To tap neurotransmitters and neuromodulators from brain neurons of anaesthetised rodents, a guide cannula is stereoractically inserted. Into a distinct brain structure. Few days after surgery the stylet of the guide cannula is replaced by a double-walled

Wine polyphenols lower blood pressure

The Mediterranean lifestyle is synonymous to a healthy lifestyle for many people. This diet is rich in vegetables, fish and olive oil, but also inseparably associated with drinking a good glass of red wine. Other alcohol-containing beverages

Alternative determination of blood alcohol concentration

Alcohol consumption is a common and legal practice in most of the countries around the world which leads to numerous fatal traffic accidents, and other incidents like leisure injuries, alcohol poisoning and drug facilitated sexual assault. According

A brain haemorrhage during anticoagulant therapy: what therapy next?

We read with interest the articles by Ntaios and by Ricci et al. concerning pros and cons of restarting oral anticoagulants (drugs that work to prevent the coagulation (clotting) of blood) after intracerebral hemorrhage. While we appreciate

HDL cholesterol: sometimes more is not necessarily better

Lipoproteins are complex particles that are responsible for transporting the water insoluble molecule, cholesterol, through the blood stream. Cholesterol is transported from the liver to peripheral tissues. Excess cholesterol in low-density lipoprotein (LDL) is deposited in the

A simple calculation using routine blood test results can identify eosinophilic asthma patients

Complete blood count (CBC) with differential, a standard test that enumerates different types of white cells in peripheral blood, is often performed during routine patient visits in clinics and hospitals. The test can be used to differentiate

Placental transfer of the HIV drug dolutegravir in a human ex vivo perfusion model

The fetus of an HIV-positive woman has a 25% chance of becoming infected during pregnancy. HIV medicines have shown to be highly effective in preventing fetal infection with HIV. A part of the efficacy but also the

HCV controls the export machinery of infected cells to increase its own spread

When a virus infects a cell it changes a lot of the cells functions and behavior to its own benefit. The virus reproduces inside the cell and forces it to release many new virus particles which can

ATF3-dependent cross-talk between cardiomyocytes and macrophages promotes cardiac maladaptive remodeling

Cardiovascular diseases are disorders of the heart and blood vessels which are leading to heart failure. Cardiovascular diseases correspond to 30% of all deaths in the world. The molecular processes that undergone from a healthy heart to

G protein signaling: a major culprit of essential hypertension

Blood pressure (BP) is the driving force that distributes the blood to the organs of the body according to their instantanous needs. It may be increased by pressor agents acting on the heart, vessels, and blood volume,

Genetic complexity in Peninsular Malaysia: a great challenge for blood donor recruitment centres

Providing safe blood and blood products (e.g. packed red blood cells, platelets and fresh frozen plasma) are important measurement in the modern era of transfusion practices. Transfusion of blood and blood products from donor to patient requires

Fragments of erythrocyte membranes are not only able to stop the bleeding, but also are able to prevent the spread of thrombosis

Red blood cells (RBCs), also called erythrocytes, are the most common type of blood cell and principal means of delivering oxygen to body tissues. Human erythrocytes develop from stem cells into mature erythrocytes in about 7 days. When matured, in a healthy individual these

Kidney angiotensinogen as a cardinal risk factor in hypertension

High blood pressure is prevalent in over 30% of the adult population and accounts for approximately one fourth of patients with heart failure, especially the elderly. The renin-angiotensin system (RAS) is of critical importance in the regulation