Tag Archives: breast cancer

Screening breast MRI in patients with personal history of breast cancer

This study looked at patients who had a personal history of breast cancer diagnosed at a premenopausal age to see if having screening breast MRI provided a benefit to the patient. Patients with a personal history of

Type of breast cancer provides clues to genetic susceptibility

Breast cancer is a common disease affecting 1 in 11 women in the UK but like many common cancers incidence increases with increasing age. Only 1 in 1,700 women younger than 30 and 1 in 228 women

Omega-3 fatty acids, obesity and breast density

Omega-3 fatty acids, abundantly present in fish oil products, are in large use among the public because of the widespread perception that they are able to ameliorate and even prevent many chronic diseases, including cancer. Our research

Importance of updating prognostic predictions: an example from breast cancer

Today prognostic prediction models are an integral part of clinical practice in many fields. They are typically used to access the risk of an event in the future after a well-defined starting point, for instance the risk

A new target in the fight against breast cancer

Cancer cells differ from normal cells in many ways, including their abnormal growth and their ability to change shape and migrate to other tissues. These differences are partly caused by changes in the production of proteins and

Breast cancer in elderly – does guideline adherent treatment really matter?

It is well known that breast cancer is currently the most common female cancer. Advances in diagnostics and treatment continuosly improve the long term outcome. To establish a new agent or therapy a randomised study with inclusion

“Chemobrain” prior to cancer treatment? The cause is probably cancer-related post-traumatic stress

Cancer patients often complain about deficits of attention, memory, and other basic cognitive functions, which considerably impact on their lives. Long time, these problems were simply attributed to side effects of chemotherapy and have therefore been termed

A functional immune system against cancer in breast cancer patients

One of the hallmarks of cancer development is the ability of tumor cells to evade the recognition by the host immune system. However, the presence of immune responses against cancer is frequently observed in cancer patients. The

Sponge toxin kills lung and breast cancer cells in mice

Peloruside A is a potent toxin that was isolated from a New Zealand marine sponge. It has a similar mechanism of action to the commonly used taxane-type anticancer drugs, including paclitaxel and docetaxel, that block the action

Protein associated with breast cancer metastasis

Breast cancer is one of the leading causes of death in women. Although there have been significant advances in diagnosis and treatment, therapy of breast cancer which has spread to other organs remains a significant challenge. It

Sugars in circulating blood reflect breast cancer biology

In our studies, consisting of measurements and analyses, we have shown that the sugar composition in the serum of breast cancer patients reflects the biology of their breast tumours. Patients with different kinds of breast tumours have

A method for studying mouse mammary tumorigenesis

Metastasis is the last step of primary breast cancer progression in which cells from the primary tumor leave and go to other organs. Breast cancer cells often metastasize to the lung, among other organs. Each step in

The art to irradiate the Internal Mammary Nodes (IMN) in breast cancer patients

Radiation therapy (RT) has demonstrated strong clinical benefit in patients with breast conservative surgery or with radical mastectomy and who are at high risk for relapse. Unfortunately, this benefit was counterbalanced by an increased risk for death

Breast cancer cells change and adapt during disease progression

A diagnosis of breast cancer usually includes characterisation of the breast cancer cells: determining if the tumour cells have hormone receptors and other proteins which will help to decide the best treatment options for the patient. This

Doctors, look up! Lack of eye contact reduces trust

Trust between breast cancer patients and their oncologist is crucial for good quality breast cancer care. It is associated with beneficial outcomes, such as a decrease in patients’ fear and better adherence. Patients’ trust was earlier shown