Tag Archives: breast

Next generation sequencing, a new gold standard for clinical gene panel testing

The adaption of the Next Generation Sequencing ( NGS ) technology to clinical laboratories has revolutionized the molecular diagnostics by reducing the costs and increasing the throughput. Clinical use of NGS enables simultaneous testing of multiple genes

The synergistic role of prolactin and estrogen in breast cancer requires PAK1

In 2016, the American Cancer Society estimates about 40,000 deaths will result from breast cancer. This makes breast cancer the second leading cause of cancer-related among women. Despite the frightening statistics, the death rates from breast cancer

A promising novel drug for breast cancer

The reason cancer is so difficult to treat is that cancer cells are our own cells running wild, which means that they generally do not make any protein or other molecule that normal cells don’t make.  This

Screening breast MRI in patients with personal history of breast cancer

This study looked at patients who had a personal history of breast cancer diagnosed at a premenopausal age to see if having screening breast MRI provided a benefit to the patient. Patients with a personal history of

Type of breast cancer provides clues to genetic susceptibility

Breast cancer is a common disease affecting 1 in 11 women in the UK but like many common cancers incidence increases with increasing age. Only 1 in 1,700 women younger than 30 and 1 in 228 women

Omega-3 fatty acids, obesity and breast density

Omega-3 fatty acids, abundantly present in fish oil products, are in large use among the public because of the widespread perception that they are able to ameliorate and even prevent many chronic diseases, including cancer. Our research

Importance of updating prognostic predictions: an example from breast cancer

Today prognostic prediction models are an integral part of clinical practice in many fields. They are typically used to access the risk of an event in the future after a well-defined starting point, for instance the risk

A novel protein called nischarin

Nischarin is a large protein that is present in the nucleus and cytoplasm of cells. So far, diseases associated with the NISCH gene include hypertension, dry mouth, morphine dependence, depression, anxiety, thick heart walls, congestive heart failure,

Locoregional treatment versus no treatment of the primary tumour in metastatic breast cancer

Stage IV breast cancer is the state in which the cancer has spread to distant sites , for example , the brain, liver, lung, bones. Treatment for stages I to III of breast cancer include surgery, chemotherapy