Tag Archives: calcification

The road to new aortic valve disease treatment: Innovations in 3D models and drug delivery

Calcific Aortic Valve Disease (CAVD) resulting in aortic stenosis is a common heart disease that affects 25% of people over 65 years old, causing 17,000 deaths per year in the USA. The aortic valve regulates blood flow

Non-canonical Wnt signaling and aortic valve stenosis

Even with the countless drugs we have to treat cardiovascular diseases, the majority of these diseases remain without a cure. Aortic valve stenosis (AVS) is one of these diseases, characterized by the narrowing of the aortic valve

Dual pathways of aortic degenerative change; Calcification and Fibrosis

Aortic stenosis (AS) is the most common type of valvular heart disease and its prevalence increases exponentially with age. Degenerative changes continue to be the most common pathologic causes. In terms of pathologic AS phenotypes, there are