Tag Archives: cell
Researchers at the universities of Cologne and Bonn uncover the link between protein aggregation and aging. Not only does our way of life determine how long we live but so too does our genetic material. Of particular
The NucleoCounter® NC-3000™ is an advanced image cytometer utilizing fluorescence imaging to characterize cell properties. The NC-3000™ can perform high speed cell count and viability determination and includes plug-and-play analytical assays of mammalian, yeast and insect cells.
The NucleoCounter® NC-200™ is a high precision automated cell counter utilizing state-of-the-art image cytometry. With user adaptable protocols and specialized assays for counting a wide range of mammalian cells, including adipose-derived stem cells, T cells, aggregated cells
Diabetes mellitus is a metabolic disorder characterized by high blood glucose (or hyperglycaemia) resulting from defects in insulin secretion from the pancreatic beta cells, insulin action, or both. The chronic hyperglycaemia produces disturbances of carbohydrate, fat and
Single cell organisms, such as amoebae, are able to live independently without the need for extracellular communication systems. However, multicellular organisms, such as insects, fish and mammals, require systems that permit individual cells to communicate to one
Non-steroidal anti-inflammatory drugs (NSAIDs) are known to act by directly suppressing the activity of cyclooxygenase, the key enzyme catalyzing the biosynthesis of prostaglandin, which induces inflammation. Therefore, NSAIDs are usually used for treating pain, inflammation, and fever.
Cancer cells differ from normal cells in many ways, including their abnormal growth and their ability to change shape and migrate to other tissues. These differences are partly caused by changes in the production of proteins and
AMP-activated protein kinase (AMPK) is a metabolic master kinase that plays a key role in maintaining energy homeostasis at cellular and whole body level. Recent evidence links AMPK activation to health benefits, such as increased longevity and
The gastrointestinal (GI) tract is a hollow tube that primarily functions to mediate the digestion of the food that we eat into forms of energy and nutrients that the cells and our body can use. The appropriate
In his treatise, James Clerk Maxwell (1873) did not only derive his famous equations but he also provided the mathematical description of the direct current (DC) resistance for dilute suspensions of shelled spherical objects. At his time,
Mass spectrometry (MS) is a technique used to measure the mass of molecules. Chemists extensively use this method to confirm that they have made the right molecule by comparing the mass of the actual product with the
In recent years, the development of new drugs and therapies has decelerated despite the application of combinatorial biochemistry and new therapeutic strategies, such as nanoparticle-based drug delivery systems. Although the numbers of newly developed compounds have steadily
Glycosphingolipids (GSLs) are amphipathic compounds consisting of oligosaccharides and hydrophobic chain of ceramide. They are ubiquitously distributed in the outer leaflet of the plasma membrane and believed to be involved in a large number of cellular processes,