Tag Archives: chemistry

Making 8-membered rings – It’s a DOS (diversity orientated synthesis) approach

For many years, the primary method of global drug discovery has involved the synthesis of naturally occurring molecules and their derivatives. This drug discovery process would involve several steps, from initial extraction and isolation from a biological

Just add water; boiling up high-performing thermoelectrics

Thermoelectric materials can realise direct conversion from thermal to electrical energy and offer unique opportunities to harvest useful electricity from waste heat. Tin selenide (SnSe) is one of the best thermoelectrics currently known as it combines an

Can a doughnut-shaped molecule help design new drugs?

Some of the most advanced and modern medicines, such as those used in the treatment of cancer rely heavily on their selective, high affinity targeting of cancerous cells in order to be effective medicine. However, some drugs

Chemistry of wonderful wet laundering

We use two types of laundries. One is dry-cleaning which is carried out using an organic solvent, and another is wet laundering is carried out using water and soap (surfactant). These observations are scientifically applied for the

Can NSAIDs alter thyroid hormone function?

Non-steroidal anti-inflammatory drugs (NSAIDs) are taken to treat pain and inflammation, and are the most frequently taken over the counter drug type taken worldwide. They work by inhibiting cyclooxygenase (COX) enzymes, whose products are used by other

Repositioning chemistry for the 21st century

A mature science developed over more than 200 years, chemistry provides understanding of the properties of atoms and molecules and practical methods for creating new molecular structures that may find useful applications. Chemistry is also an enabling

Probing how alcohol affects the structure of water

Water, despite its ubiquity, is an extraordinarily complex substance. The structure of water on a molecular level is defined by the interactions, “hydrogen bonds”, that individual molecules have with each other. These are the reason that upon

Advanced green antibacterial materials made by mussel-inspired chemistry

Since ancient times, silver and its salts have universally been employed as antibacterial agents for the treatment of infections, burns and chronic wounds in curative and preventive health care, because of their extraordinary inhibitory and bactericidal properties

Operationally simple reactions with unprotected carbohydrates – an application of organocatalysis

Carbohydrates are ubiquitous in nature. They play an important role as an energy reservoir as well as they are the resource of countless biomaterials, such as cellulose or chitin. This importance has challenged chemists at all times