Tag Archives: diabetes

The role of oxidative stress in Type 2 diabetes

Type 2 diabetes is a major health concern that affects people no matter their gender, race, or socio-economic background is. In type 2 diabetes, a person’s body stops responding efficiently to insulin after a meal. This desensitization

Assessing the evidence on weight loss strategies

Weight loss and weight management is of upmost importance in our current climate of increasing rates of overweight and obesity and of associated diseases like type 2 diabetes. Here the evidence on weight loss strategies, in people

Bimetallic nanoparticles-based biosensor for managing diabetes

The glycated hemoglobin test gives the information about average level of blood sugar over the past 2 to 3 months. It’s also called HbA1c, glycated hemoglobin test, and glycohemoglobin. Persons who have diabetes require this test regularly

B-vitamins over-consumption may be the cause of the increased prevalence of obesity and diabetes

Obesity and type 2 diabetes have been a major health issue in the United States. It is during the past few decades that obesity and type 2 diabetes have rapidly reached epidemic levels not only in adults

Does statins increase risk of diabetes?

Statins are drugs that inhibit the enzyme 3-Hydroxy-3-methylglutaryl-coenzymeA (HMG-CoA) which is critical in the production of cholesterol molecules. Thus is commonly used in the treatment of abnormally elevated cholesterol which is known to contribute to cardiovascular disease

Modern medicine is poisoned by professional arrogance

Modern medicine is poisoned by professional arrogance. The antidote is professional humility. The arrogance is exacting a high price. Several examples prove the point. For forty years physicians regularly irradiated the thymus glands of children because of

The most effective system to weight lost

People who suffer from morbid obesity are at high risk for many diseases, atherogenic dyslipidemia, elevated blood pressure, type 2 diabetes, thromboembolism, hepatic steatosis, proinflammatory state, etc. Metabolic syndrome is characterized by the clustering of some, or

Electrically controlled insulin release

Stimuli responsive materials are promising for designing the next generation of drug delivery systems. Such materials would enable drugs to be released on-demand or in response to patient needs, specifically at the target site, minimizing side effects.

Vistafin and endothelial progenitor cell dysfunction in diabetes mellitus

The prevalence of type 2 diabetes mellitus (T2DM) has been increased over recent decades, reaching worldwide epidemic. T2DM continues to exhibit a substantial impact on global health and requires increased expenditures of economic resources and medical care,

Type I interferons fuel adipose inflammation in obesity

When people get fat the visceral adipose tissue (VAT), fatty deposits inside the body that cling around the internal organs, get inflamed. This chronic low grade inflammation is termed metaflammation. Metaflammation has been found to contribute to

Gold-silver nanoparticles instead of traditional diabetic drugs

Recently, we have published a pioneering work on green biosynthesis and complete characterization of gold and core shell silver-gold nanoparticles (AuNPs and Ag@AuNPs) via using green biopolymer in the influence of microwave radiation. These synthesized nanoparticles provide

Diabetes and the heart – role of CT in predicting outcomes

People suffering from adult type diabetes mellitus have an increased tendency to develop disease of large and small arteries. Disease of the coronary arteries of the heart may lead to chest pain on exercise (angina pectoris) or

Reducing cellular stress may prevent diabetes complications

Poorly controlled diabetes is often associated with various complications including blindness, kidney failure and pain secondary to damaged nerves. However, the most common complications are those related to large blood vessel disease such as heart attacks and

Oligomers are building blocks of amyloid formation for insulin and its fast analog LisPro

The hormone insulin was discovered in 1921 by Banting and Best, and since that time it has been studied rigorously. At the same time first attempts were made to use insulin for treating diabetes. Insulin was the

Small fish can help finding drugs to fight retina diseases

About 285 million people are visually impaired in the world. The arising of chronic eye diseases and ageing processes make more people at risk of blindness, 65% of visually impaired people being aged 50 or older. Among

Prevention of type 2 diabetes: Prevention of beta cell “karoshi”

The number of patients with type 2 diabetes (T2DM) continues to increase despite the recent advances in pharmacological therapies for T2DM. This fact indicates that we still may not sufficiently understand the pathophysiology of this disease. By

Early treatment with basal insulin glargine in people with type 2 diabetes: Lessons from ORIGIN and other cardiovascular trials

The inability to control blood glucose levels can result in many negative health outcomes including eye, kidney, cardiovascular (heart) and foot disease, and early death.  Persons with type 2 diabetes are 2 to 4 times more likely

Oxytocin and human Central Diabetes Insipidus in relation to the different hydromineral animal models

Central Diabetes Insipidus (CDI) is a disorder caused by a deficit in the production of arginine vasopressin (AVP), a hormone that acts by binding to AVP receptor 2 (AVPR2) on the kidney collecting tubule cells and produces

Prevalence of hospitalisation resulting from medicine related problems among adult patients with cardiovascular diseases and/or diabetes

Cardiovascular diseases ( CVDs ) and diabetes ( DM ) are two interrelated groups of diseases that contribute to more than 50 % of death worldwide. Patients with CVDs and / or DM often take multiple medicines

Long-term outcome in patients admitted with a heart attack and detected with increased blood sugar levels during admission

An Oral Glucose Tolerance Test ( OGTT ) is one of the diagnostic tests to determine the presence of pre – diabetes or manifest diabetes. An OGTT involves drinking a 75 gram sugar solution after 8 hours