Tag Archives: diabetes

Vistafin and endothelial progenitor cell dysfunction in diabetes mellitus

The prevalence of type 2 diabetes mellitus (T2DM) has been increased over recent decades, reaching worldwide epidemic. T2DM continues to exhibit a substantial impact on global health and requires increased expenditures of economic resources and medical care,

Type I interferons fuel adipose inflammation in obesity

When people get fat the visceral adipose tissue (VAT), fatty deposits inside the body that cling around the internal organs, get inflamed. This chronic low grade inflammation is termed metaflammation. Metaflammation has been found to contribute to

Gold-silver nanoparticles instead of traditional diabetic drugs

Recently, we have published a pioneering work on green biosynthesis and complete characterization of gold and core shell silver-gold nanoparticles (AuNPs and Ag@AuNPs) via using green biopolymer in the influence of microwave radiation. These synthesized nanoparticles provide

Diabetes and the heart – role of CT in predicting outcomes

People suffering from adult type diabetes mellitus have an increased tendency to develop disease of large and small arteries. Disease of the coronary arteries of the heart may lead to chest pain on exercise (angina pectoris) or

Reducing cellular stress may prevent diabetes complications

Poorly controlled diabetes is often associated with various complications including blindness, kidney failure and pain secondary to damaged nerves. However, the most common complications are those related to large blood vessel disease such as heart attacks and

Oligomers are building blocks of amyloid formation for insulin and its fast analog LisPro

The hormone insulin was discovered in 1921 by Banting and Best, and since that time it has been studied rigorously. At the same time first attempts were made to use insulin for treating diabetes. Insulin was the

Small fish can help finding drugs to fight retina diseases

About 285 million people are visually impaired in the world. The arising of chronic eye diseases and ageing processes make more people at risk of blindness, 65% of visually impaired people being aged 50 or older. Among

Prevention of type 2 diabetes: Prevention of beta cell “karoshi”

The number of patients with type 2 diabetes (T2DM) continues to increase despite the recent advances in pharmacological therapies for T2DM. This fact indicates that we still may not sufficiently understand the pathophysiology of this disease. By

Early treatment with basal insulin glargine in people with type 2 diabetes: Lessons from ORIGIN and other cardiovascular trials

The inability to control blood glucose levels can result in many negative health outcomes including eye, kidney, cardiovascular (heart) and foot disease, and early death.  Persons with type 2 diabetes are 2 to 4 times more likely

Oxytocin and human Central Diabetes Insipidus in relation to the different hydromineral animal models

Central Diabetes Insipidus (CDI) is a disorder caused by a deficit in the production of arginine vasopressin (AVP), a hormone that acts by binding to AVP receptor 2 (AVPR2) on the kidney collecting tubule cells and produces

Prevalence of hospitalisation resulting from medicine related problems among adult patients with cardiovascular diseases and/or diabetes

Cardiovascular diseases ( CVDs ) and diabetes ( DM ) are two interrelated groups of diseases that contribute to more than 50 % of death worldwide. Patients with CVDs and / or DM often take multiple medicines

Long-term outcome in patients admitted with a heart attack and detected with increased blood sugar levels during admission

An Oral Glucose Tolerance Test ( OGTT ) is one of the diagnostic tests to determine the presence of pre – diabetes or manifest diabetes. An OGTT involves drinking a 75 gram sugar solution after 8 hours

Can you reduce your risk of diabetes with lifestyle changes?

Glucose homeostasis deficiency may lead to chronic increase in blood glucose levels and could affect a large number of tissues and organs.  The shift from early metabolic abnormalities that forego diabetes, such as impaired fasting glucose and

Optimizing diabetes care on a global scale

Diabetes is a major threat to healthy living for hundreds of millions of people worldwide.  Type-1 diabetes must be treated with insulin and type-2 diabetes (the more common form) can be treated with lifestyle changes, oral medication,

AMPK: How can we amp it up to fight disease?

The high prevalence of obesity, insulin resistance, type 2 diabetes and cardiovascular disease has made it clear that we need a better understanding of how our bodies store and use energy when we overload them with excess

Active role of cell-derived microparticles in diabetes associated cardiovascular complications

Diabetes mellitus is a metabolic disorder characterized by high blood glucose (or hyperglycaemia) resulting from defects in insulin secretion from the pancreatic beta cells, insulin action, or both. The chronic hyperglycaemia produces disturbances of carbohydrate, fat and