Tag Archives: differentiation

Novel arginine demethylase function of JMJD1B gene controls cell fate decision of blood progenitors

Epigenetic modifications such as post-translational modifications (PTMs) of histone proteins and DNA methylation dynamically changes in cells to fine-tune the expression of genes required for normal cellular function. These epigenetic modifications involve in nearly all cell fate

Understanding cardiac arrhythmias using an embryonic stem cell model

Embryonic stem cells are pluripotent and have the capability to differentiate into almost all cell types of the body. Thus, they offer great potential for regenerative medicine such as cell-based therapies and basic research purposes including disease

Turing instability: life’s unique defiance of the second law of thermodynamics

Our psychological ‘arrow of time’ is conditioned by the Second Law of Thermodynamics, i.e. by the law of increase in entropy. A drop of blue ink will spread in water, as would white milk in black coffee.

Specific epidermal layers engineered by using polymeric membranes

Advances in tissue engineering led to the realization of human bioengineered skin substitutes for in vivo skin regeneration and in vitro applications. Notably, in vitro skin models are useful tools alternative to animal experimentation for testing the

What stem cells have to do with stomach cancer

The surface of the stomach is lined by a delicate single-layered sheet of epithelial cells (termed the gastric mucosa and its glands), which represents a tight barrier to the outside world (i.e., the gastric juice and its

Use of an in vitro model of blastema tissue from Rabbit pinna

Rabbit ear wound repair is an accepted model for studies of tissue regeneration, leading to scar less wound repair. It is believed that a specific tissue, blastema, is responsible for such interesting capacity of tissue regeneration. To