Tag Archives: drug discovery

3rd International Conference and Expo on Drug Discovery & Designing. Vienna, Austria. October 02-04, 2017

Conference Series has taken an initiation to conduct international conference and Expo on Drug Discovery & Designing workshops worldwide . From last 3 years Conference Series has been conducting Drug Discovery & Designing conferences in major continents

A multistep virtual screening approach to identify proteasome inhibitors

Proteasome plays a fundamental role in the protein turnover by degrading misfolded, abnormal or damaged proteins, previously labeled through addition of a polyubiquitin chain. An aberration of this proteolytic system could result in different types of hematological

Small fish can help finding drugs to fight retina diseases

About 285 million people are visually impaired in the world. The arising of chronic eye diseases and ageing processes make more people at risk of blindness, 65% of visually impaired people being aged 50 or older. Among

The apothecary inside us

New drugs might be found right under our noses or, more precisely, in our guts as we learn more about the ways metabolites from intestinal bacteria modulate human metabolic and immunity pathways.  Our recently published paper in

Combining paper-based electrochemistry and mass spectrometry

Electrochemistry / mass spectrometry ( EC / MS ) has many applications in science and industry such as drug discovery, elucidation of redox mechanisms, identification of drug metabolites, and online chemical derivatization for improving analytical figures of

Making drug discovery more efficient: predicting drug side effects in early screening efforts

Drug research and development is a complex and expensive process that begins with initial screening steps of candidate chemical compounds. Compounds that appear to have the desired potency against a specific cellular target or pathway are further

Small fish can help finding antimalarial drugs with less severe side effects

In 2012, over 200 million cases of malaria have been reported. Vaccines for malaria are under development; however, no generally accepted vaccine that also works for adults is yet available. Therefore, drugs will in the foreseeable future

Finding new drug targets to prevent heart attacks and strokes

Heart attacks and strokes are responsible for more deaths than any other disease in the world. The underlying cause of most heart attacks and strokes is a disease of the blood vessels called atherosclerosis. Atherosclerosis involves accumulation

3D environment enhance cellular capacities

Although we live under the 3D (three-dimensional) environment, drug testing is carried out usually by using isolated cells cultured under the 2D (two-dimensional) environment. Liver is a very important organ which metabolizes glucose, alcohol, lipids (e.g. cholesterol)