Tag Archives: drug

3rd International Conference and Expo on Drug Discovery & Designing. Vienna, Austria. October 02-04, 2017

Conference Series has taken an initiation to conduct international conference and Expo on Drug Discovery & Designing workshops worldwide . From last 3 years Conference Series has been conducting Drug Discovery & Designing conferences in major continents

Artemisia annua leaves improved solubility of antimalarial drug, artemisinin

Artemisia annua L., also known as Sweet Annie, is a Chinese medicinal herb that produces the important antimalarial drug, artemisinin. Artemisinin is the most powerful antimalarial ever discovered and its derivatives are the main component of artemisinin

Simple mathematical formulas for tracking the number of antibiotic resistance cases globally

In order to continue to live, microbes and germs have found ways to prevent drugs from killing them in the process of curing patients—when the patients ingest the drugs for treatment. Microbes destroying drugs within patients and

Glutathione-responsive co-assembly hydrogel for controllable drug release

Glutathione-responsive nano-vehicles have gained considerable interest because several intracellular compartments such as cytosol, mitochondria, and cell nucleus contain a high concentration of glutathione (GSH, 2-10 mM) tripeptides, which is 100-1000 times higher than that in extracellular fluids

Are less expensive “biosimilar” drugs as effective at treating ankylosing spondylitis?

Ankylosing spondylitis (AS) is a type of arthritis caused by inflammation, in which the main symptom is back pain. When a substance called tumour necrosis factor (TNF) is over-active in the body, it causes inflammation and damage

Can a doughnut-shaped molecule help design new drugs?

Some of the most advanced and modern medicines, such as those used in the treatment of cancer rely heavily on their selective, high affinity targeting of cancerous cells in order to be effective medicine. However, some drugs

Clues for innovative therapies targeting the c-ring of the F1FO-ATP synthase

Increasing evidence points out that the ATP synthase/hydrolase, also known as F1FO-complex, can be the key enzymatic switch between cell life and death. So, the enzyme complex, which bears the task of building most cellular ATP, the

A new drug target for healthful aging

With the aging population of the United States increasing every year, there is an increasing need to develop new therapeutic modalities to provide for healthful aging. Although longevity is generally considered positively in most families, and of

Special molecular mechanism makes CD147 an interesting drug target in cancer or autoimmune diseases

T cells are important players of the immune system, recognizing foreign or dangerous agents with their unique receptors. They defend the body from these agents either directly by killing or by recruiting or regulating other immune system

An international team opens new avenues toward PKU therapy

When a baby is born, a simple blood test reveals whether the child has PKU, which is a recessive genetic disorder where the body fails to regulate the amount of phenylalanine (Phe) in blood.  Phe is a

The apothecary inside us

New drugs might be found right under our noses or, more precisely, in our guts as we learn more about the ways metabolites from intestinal bacteria modulate human metabolic and immunity pathways.  Our recently published paper in

Using computers to understand the deposition of pollutant and therapeutic aerosols in the human lungs

In an urban setting, suspended pollutant particles enter our lungs along with air we inhale.   A good portion of them gets deposited on our airways, often inducing toxic effects. A young child or an elderly patient facing

Continuing the age of discovery in cardiovascular disease

A rare genetic defect involving the heart muscle is leading to early heart failure and potentially lethal heart rhythms for patients in Saudi Arabia. This disease, called Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia or ARVC/D, involves healthy heart muscle

Prompt resolution of essential drug intolerance

The gut is nowadays seen as a site of cross-talk and interchange between the inner body (supposed to be sterile, namely free of viable harmful bugs) and the outer contaminated world, mainly entering the digestive tract through

Drugs and drowning

Electrical activity of the heart is commonly monitored by the electrocardiogram (ECG).   Such electrical activity depends on certain proteins called ion channels.  These channels control the timing and the flow of electrically charged particles (ions) in and

Improving nature’s own communication system to fight cancer

Our bodies are composed of trillions of different cells, which communicate with each other in order to keep us healthy. There are several ways in which messages can be sent back and forth between cells. One of