Tag Archives: epilepsy

Epileptic encephalopathies in children: Animal models may change the word “catastrophic” to “hopeful”

Seizures are a sign of brain dysfunction caused by abnormal, hyperexcitable brain circuits. Clinical seizures range from brief staring spells to massive whole – body convulsions. The developing brain is especially prone to seizures and seizure-related brain

Did Joan of Arc and Saint Paul suffer from epilepsy?

In February 2016, I read an article written by two Swiss neurologists trying to demonstrate that Joan of Arc’s and Saint Paul’s visual and auditory experiences were all manifestations of underlying epilepsy.  The article was published in

Cerebral herniation into the sigmoid sinus: A newly-realized cause of epilepsy

Epilepsy is a chronic disorder characterized by recurrent seizures, which may vary from a brief period of lapse of attention or muscle jerks, to severe and prolonged convulsions. The seizures are caused by sudden, usually brief, excessive

Medicines – allergic reactions to antiepileptic drugs

Around 1% of the global human population – ca. 65 million – suffer from epilepsy – a chronic neurological disease with one of the most prominent symptoms being so called epileptic seizures. With a range of antiepileptic

Heart and blood pressure adverse effects of phenytoin

Phenytoin is an effective antiepileptic drug which is used for many years in the treatment of epileptic seizures. Whereas its oral form is used for the long-term treatment of epilepsy, the intravenous form – the injection into

Isovaline, a compound first identified in the Murchison meteorite, shows potential for treating Epilepsy

Epilepsy is a brain disease that affects 65 million people worldwide and is characterized by seizures that arise from hyper-active and hyper-connected brain cells. Typically, the first approach for managing seizures is treating individuals with pharmaceuticals. However,

Epileptic rats as perfect models to understand epilepsy?

Epilepsy is a neurological disease that affects about 1% of the population in the world, most of them being children and teenagers. Animals suffering from epileptic seizures can also be found in several species (dogs, cats, chicken,

Too much or too little of one gene, CHRNA7, is associated with many neuropsychiatric disorders

In the human genome, certain regions are unstable and are found to have missing ( deletions ) or extra ( duplications ) pieces of chromosome. Many of these deletions and duplications have been implicated in neurological disease,

Epilepsy spectrum disorders

Symptoms of mental illness (like depression or hallucinations) tend to change slowly overtime (with or without treatment). At time individuals may experience episodic symptoms like sudden and brief panic attacks or sudden and brief violent episodes. While

Antiepileptic property of vitamin B12 in one animal model

Epilepsy –a serious neurological disorder that affects millions of people worldwide– is usually associated with a disturbance of normal activity of the brain, and in most typical form, is accompanied by seizures. Various antiepileptic drugs with different

Good long-term employment outcomes after epilepsy surgery in Sweden

Epilepsy is one of the most common chronic neurologic disorders and affects all domains of life. About one third of people with epilepsy still have seizures despite antiepileptic drug treatment. Drug resistant epilepsy strongly impairs quality of