Tag Archives: genetic

Characteristics of children with familial and idiopathic dilated cardiomyopathy

Dilated Cardiomyopathy (DCM) is a disease characterized by weakening of the heart muscle that becomes dilated and unable to pump blood efficiently. DCM is diagnosed in 0.57 of 100,000 children per year in North America and has

Genetic and non-genetic animal models for Autism Spectrum Disorders

Autism spectrum disorder (ASD) is a heterogeneous group of neurobehavioral problems with genetic and environmental origins. The major neurobehavioral changes are manifested by persistent deficits in social and communication interaction, deficits in developing, understanding and maintaining relationships,

Genetic differences in elite rugby players and the general population

We have known for many years that genetic variation is important in understanding any physiological trait and contributes substantially to the way people develop. Height for example is estimated as being ~80% determined by genetic variation with

The potential of LINGO-1 as a therapeutic target for essential tremor

Essential tremor (ET) is probably the most common movement disorder. Because the etiology of ET is unknown, treatment of ET is symptomatic and is geared towards reducing the patient’s embarrassment and disability. The first line treatment is

A novel reovirus mutant: toward the next generation of viruses for cancer treatment?

In the last decade or so, it has been realized that viruses are not only foes to fight, but possible therapeutics against diseases such as cancer. Most of these so-called oncolytic viruses are engineered to acquire desirable