Tag Archives: hematopoiesis

Inner myeloid gene network as a nexus of hematopoiesis and infection

The immunological system is equipped with efficient and tunable mechanisms to remove immediately pathogens from our body. Invasion of microbes in the blood is an emergency state, because they can trigger inflammatory responses, leading to sepsis. Therefore,

Cellular barcoding: giving names to every stem cell

There are many different cell types in the blood, all of different functions and shapes. All these cells are made by the stem cells by a process of lineage commitment and differentiation. How can we monitor this

“Good kids in bad neighborhoods” – the role of bone marrow microenvironment in the development of acute myeloid leukemia

Acute myeloid leukemia (AML) is the most common and aggressive blood cancer in adults and is associated with a high rate of mortality due to cancer therapy resistance and disease relapse. AML is characterized by severe deficiency