Tag Archives: human

Profiling biologics in circulating human whole blood

Functional and safety assessments of biologics prior to first-in-human (FIH) is key to understand the mode-of-action and safety profile. We have made use of an ex-vivo whole blood assay for its potential in assessment of antibody-based drug

Non-canonical Wnt signaling and aortic valve stenosis

Even with the countless drugs we have to treat cardiovascular diseases, the majority of these diseases remain without a cure. Aortic valve stenosis (AVS) is one of these diseases, characterized by the narrowing of the aortic valve

In the pursuit of personalized medicine; New technologies to study the gut microbiome

Humans have a symbiotic relationship with microbes that reside in and on our bodies.  The human digestive tract contains as many as 1014 of bacterial cells, making it one of the densest and most diverse microbial communities

Spectroscopy of biophotons radiated from a fingertip

What color of light beams are emitting from your fingertips? That is neither a fantasy nor an occult question. If you possessed eyes of extremely high-sensitivity or had a special CCD camera like one used for a

Human motor neurones: so well-known or still unknown?

Movements, the fundamental base of normal human life, are produced when our skeletal muscles contract and relax, submitting to control by special nervous cells, the so-called motor neurones (motoneurones) placed in the spinal cord. It is surprising

The European Human Behaviour and Evolution Association (EHBEA)

London, UK, from 5-8 April The European Human Behaviour and Evolution Association (EHBEA) is an interdisciplinary society that supports the activities of European researchers with an interest in evolutionary accounts of human cognition, behaviour and society. EHBEA

Binding study of fibrinogen and albumin to metal oxide nanoparticles and its relevance in nanomedicine

The binding of proteins to different inorganic surfaces plays an important role in natural processes such as the growth of bone tissue (protein-mineral interactions) and in biotechnological and biomedical applications. Recently, the binding of proteins to metal

Human papillomavirus infection and vaccination

Human papillamoavirus (HPV) is an infection that can be sexually transmitted. A person can get HPV by having vaginal, anal, or oral sex with another person who has the virus. HPV infections are the most common sexually

Meat traditions (and the co-evolution of humans and meat)

If food is indeed “good to think”, as in Lévi-Strauss’ famous maxim, then meat seems to be the supreme example. Meat is truly about us. Besides, the way we deal with meat needs urgent reconsideration due to

How to lower a risk of being bitten to the face by a dog

Dogs are the most popular pets. They are used for guarding, hunting, and many other purposes. Additionally, dogs are ideal human companions. However, the mutually beneficial relationships between people and dogs are sometimes overshadowed by bites. Among

Is HDL cholesterol always good for you? Surprises, overturns and promises

According to the World Health Organization, coronary heart disease is a major cause of death worldwide. In 2008, 17.3 million people died from heart disease, and this number is expected to rise further, reaching an estimated of