Tag Archives: immune system

Identification of a new T cell regulator

T-cell receptor (TCR) signaling is mediated by the activation of protein-tyrosine kinases such as p56lck and ZAP-70. In mature T-cells, CD4 and CD8 molecules bind to p56lck which then phosphorylates the intracellular immune-receptor tyrosine-based activation motifs (ITAM)

Hitting the sweet spot: Sialic acid sugars for the treatment of immune diseases and other disorders?

In addition to DNA, proteins and lipids, sugar molecules are essential building blocks for every living cell. There are many different types of sugar molecules in a cell which are linked to one another forming chain or

Special molecular mechanism makes CD147 an interesting drug target in cancer or autoimmune diseases

T cells are important players of the immune system, recognizing foreign or dangerous agents with their unique receptors. They defend the body from these agents either directly by killing or by recruiting or regulating other immune system

Is our immune system mistaking tumours for foetuses?

Tumours are abnormal growths of tissue where cells produced by the body get out of control and divide at a rapid and unregulated pace. And – when you think about it – embryos too are masses of

Identification of drusen characteristics in age-related macular degeneration

In this study, we investigated the morphologic characteristics of drusen in order to determine their composition, using an in-vivo technique, the optical coherence tomography (OCT). The development of drusen is an important characteristic of age-related macular degeneration

Pancreatic cancer and innovative treatment: the seeming paradox to block the immune response

Pancreatic cancer (PC) is the 5th leading cause of cancer‐related death in the developed world with more than 260,000 annual deaths worldwide and with a dismal 5‐year survival (5%). The lethality of pancreatic cancer is due to

Antibodies at your pipette tips

Antibodies are essential in our immune system to fight against all sorts of diseases that we could encounter every day. The technological developments over the decade has allowed scientist to isolate target or disease-specific antibodies in the

A functional immune system against cancer in breast cancer patients

One of the hallmarks of cancer development is the ability of tumor cells to evade the recognition by the host immune system. However, the presence of immune responses against cancer is frequently observed in cancer patients. The