Tag Archives: inflammatory

P2X7 antagonism: a specific tool to decrease inflammatory status in human atherosclerotic vessels?

Atherosclerosis is a dynamic progressive disease of the large arteries characterized by the tendency to accumulate lipids, inflammatory cells, smooth muscle cells and extracellular matrix within the sub-endothelial space, and progressing in unpredictable way to different stage.

Inflammatory bowel disease: one, two, or a thousand diseases

The so-called Inflammatory Bowel Diseases (Ulcerative Colitis –UC- and Crohn’s Disease –CD-, comprised under the umbrella acronym IBD) often come about with the accompaniment of variegated pathologic conditions that are mostly inflammatory in nature. Among them, the

Multiple injuries (polytrauma) result in skeletal muscle wasting and insulin resistance

Polytrauma is a combination of injuries that occur over a short period of time (simultaneously or within minutes of each other). These injuries can include burn, fracture, hemorrhage, trauma to the extremities, or penetrating trauma to the

Prompt resolution of essential drug intolerance

The gut is nowadays seen as a site of cross-talk and interchange between the inner body (supposed to be sterile, namely free of viable harmful bugs) and the outer contaminated world, mainly entering the digestive tract through

Nonsteroidal anti-inflammatory drugs attenuate lung carcinogenesis in smoking female mice

Chronic inflammation plays a crucial role in the development of cancer in general and of cigarette smoke (CS) – related lung cancer in particular. Accordingly, anti-inflammatory drugs, among which the extensively used nonsteroidal anti – inflammatory drugs

Highlighting inflammatory markers in anxiety disorders

Anxiety disorders, often originating early in life, are very common and effect 28.3% of the population. With this high prevalence comes an associated cost to the economy, mostly related to the extensive overuse of primary care services

Researchers describe “imm-unifying theory” capable of explaining multiple medical problems

About a year ago, investigators at the Shock Trauma Center in Baltimore, MD found that patients who had organ transplants fared quite well after traumatic events. The authors of the manuscript, which was published in the Journal