Tag Archives: insulin resistance

Type I interferons fuel adipose inflammation in obesity

When people get fat the visceral adipose tissue (VAT), fatty deposits inside the body that cling around the internal organs, get inflamed. This chronic low grade inflammation is termed metaflammation. Metaflammation has been found to contribute to

Insulin effects on pancreatic beta cells-not always what you may think

Normally, blood glucose levels are controlled within a reasonable range by the release of insulin from pancreatic beta cells in response to an increase in blood glucose levels following a meal or other glucose challenge. One of

Low salt intake during pregnancy

All cells of an organism share the same DNA sequence from the time they are stem cells until they are fully differentiated, differing greatly in relation to the profile of expressed genes. Changes in gene expression which

The vicious cycle in liver that fuels the obesity diabetes pandemic

Experimental obesity is readily produced by dietary excesses of fats or carbohydrates and involves an initial increase in glucose production by the liver with subsequent increases in blood insulin levels, i.e., an insulin-resistant state. In turn, elevated