Tag Archives: metastasis

Altered expression of a protein in high vs. low spreading cancer cells

Breast cancer cells start off growing in the breast and end up spreading to the lung, liver, bones and brain. This spreading to another organ is called metastasis and is the major cause of patient death due

Melanoma is controlling metastasis of melanoma – fact or a myth?

The title is provocative, because most will most ask: but who other than mm can control the metastasis of melanoma? But let’s get on the path of facts and procedures about melanoma diagnosis, follow-up and treatment of

Treatment holidays for patients with metastatic kidney cancer

Targeted therapy is the standard treatment of patients with metastatic cancer of the kidney. The best current therapies target the tumour vasculature thereby blocking the access of the tumour to nutrients and limiting possibility of spreading to

Computational systems biology in cancer brain metastasis

Cancer metastasis, especially cancer brain metastasis, is a complicated process representing the major cause for cancer-related deaths worldwide. A better understanding of the underlying mechanisms of such malignancies will enable us to develop more efficient therapeutic strategies.

A replacement for chemotherapy?

Metastasis is a process where cancer cells of primary tumors gain properties enabling them to escape from the primary tumor and move to a secondary location in the body where they develop additional tumors. This event in

Diagnosis of small cell lung carcinoma metastases

Cancer is defined by unscheduled cellular growth and metastatic spread into other organs of the body. Tumor cells gain their capacities form genetic alterations, also known as mutations, leading to altered protein functions and signaling pathways. Tumors

How can cancer cells use hydrogen peroxide to strive?

Hydrogen peroxide (H2O2) is a well-known antiseptic used in our homes since the 1920s. But did you know that our cells produce this molecule and that at low concentrations H2O2 instructs our cells to do different things,

CITED1 is a potential therapeutic target for metastatic melanoma

Cancer kills over 8 million people every year. What makes it so deadly is its ability to spread from the organ where it originates to the rest of the body, a process known as metastasis. Even though

Radiation therapy for nerve pain when cancer spreads to bones

One of the hallmarks of cancer is its ability to spread from the primary site of origin to other places in the body.  Such secondary sites are called “metastases”.  One of the commonest sites for cancer secondaries

Protein associated with breast cancer metastasis

Breast cancer is one of the leading causes of death in women. Although there have been significant advances in diagnosis and treatment, therapy of breast cancer which has spread to other organs remains a significant challenge. It