Tag Archives: methylation

What it takes to survive a transplant

Many patients with blood cancers, such as multiple myeloma, leukemia, or lymphoma, have radiation treatment or chemotherapy to destroy their tumor cells and diseased bone marrow. Unfortunately the treatment damages their immune system leaving them immunocompromised. To

MSX1 sensitises cells to ovarian cancer treatment

Ovarian cancer is an insidious disease which in the majority of cases is diagnosed only at a very late stage. The majority of ovarian tumours are of a particular aggressive type, called high grade serous ovarian cancer.

Methylation profile of DMPK gene in myotonic dystrophy type 1 (DM1)

Myotonic dystrophy type 1 (DM1, Steinert’s disease), is the most common muscular dystrophy in adult life, characterized by myotonia (prolonged muscle contractions), muscle weakness, cataract, cardiac disease, gastrointestinal abnormalities, and central nervous system dysfunction. The clinical spectrum

A new dimension in the study of life?

One of the key remaining questions in biology is how different cell types originate from single cells such a fertilized eggs or cells from early embryos. What factors drive cells to adopt one cell fate over another?