Tag Archives: nucleus

Determination of the size of folding nuclei of fibrils formed from Aβ(1-40) peptide

One of the most important models for studying amyloid fibril formation is the Aβ peptide, aggregates of which form plaques in the course of Alzheimer`s disease. Formation of Aβ aggregates goes through the nucleation mechanism with exponential

Image Cytometer – NucleoCounter® NC-3000™

The NucleoCounter® NC-3000™ is an advanced image cytometer utilizing fluorescence imaging to characterize cell properties. The NC-3000™ can perform high speed cell count and viability determination and includes plug-and-play analytical assays of mammalian, yeast and insect cells.

NucleoCounter® NC-200™ – Automated Cell Counter

The NucleoCounter® NC-200™ is a high precision automated cell counter utilizing state-of-the-art image cytometry. With user adaptable protocols and specialized assays for counting a wide range of mammalian cells, including adipose-derived stem cells, T cells, aggregated cells

One of the mechanisms of amyloid fibrils formation based on the sizes of folding nuclei of Aβ40 and Aβ42

Antibiotics and various advances in medical treatment have led to overall growth of life expectancy. However, along with positive aspects of prolonged life, humanity has faced a new challenge – age-related deceases. Parkinson’s disease along with Alzheimer’s

Nucleus-targeted anticancer drug delivery

Tumor cell nucleus-targeted delivery of antitumor agents is of great interest in cancer therapy, since the nucleus is one of the most frequent targets of drug action. However, efficient nuclear drug delivery upon systemic administration remains a

The role of the thalamic submedius nucleus histamine in modulation of formalin-induced orofacial pain

Pain is one of the most common and disturbing of human experiences. While it has many causes, the appreciation of painful sensation depends on the stimulation of pain receptors (nociceptors) and the conduction of the nerve impulses

A better understanding of cell division by combining mathematical modeling and experimentation

The cell division cycle is the process by which a growing cell replicates its genome and partitions the two copies of each chromosome to two daughter cells at division. It is of utmost importance to the perpetuation

The interplay of the ticking clock and miRNA in differentiation of endothelial precursors

Our day-today activities like sleep-wake cycle, hormone release, body temperature and other important bodily functions follow a characteristic rhythm over 24 hours called a circadian rhythm. A ‘master clock’ in brain termed as suprachiasmatic nucleus (SCN) co-ordinates

A novel protein called nischarin

Nischarin is a large protein that is present in the nucleus and cytoplasm of cells. So far, diseases associated with the NISCH gene include hypertension, dry mouth, morphine dependence, depression, anxiety, thick heart walls, congestive heart failure,