Tag Archives: pancreatic cancer

Pancreatic cancer stem cells: fatty acid synthesis and mevalonate pathways are implicated in their survival

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with a high metastatic potential. The disease is the fourth leading cause of cancer-related deaths in the USA, and is projected to be the second one by 2030, due

Positron Emission Tomography can visualize pancreatic cancer tumor changes during chemotherapy and predict longer survival

Pancreatic cancer is one of the most deadly cancer types. Only 20% of patients live beyond 1 year after diagnosis because of the aggressive nature of this disease and ineffective treatments. Therefore it is crucial to recognize

The molecular analysis of tumor cells in pancreatic tissue – searching for a needle in a haystack

In cancer research usually the tumor cell specific abnormalities are of interest: gene mutations, production of abnormal proteins, production of abnormal quantity of proteins, tumor cells treatment response. But the molecular analysis of pancreatic tumor samples poses

Pancreatic cancer and innovative treatment: the seeming paradox to block the immune response

Pancreatic cancer (PC) is the 5th leading cause of cancer‐related death in the developed world with more than 260,000 annual deaths worldwide and with a dismal 5‐year survival (5%). The lethality of pancreatic cancer is due to

Granule formation in pancreatic acinar cells

The pancreas is an important gland organ within the digestive and endocrine system of vertebrates. It is both an endocrine and exocrine gland. The endocrine part produces several important hormones such as insulin which are released in

Surgery for pancreatic head cancer

Pancreaticoduodenectomy (PD) offers the only chance of long-term survival for patients with pancreatic head cancer. The procedure involves removing the pancreatic head together with the duodenum, gallbladder and most of the common extra hepatic bile duct (Fig.

Using nanotechnology to outsmart pancreatic cancer

Cancer is a versatile disease and makes use of complex cellular signaling networks to defend itself against a host of treatments. Pancreatic cancer in particular has proven challenging with tenacious resistance to DNA-damaging chemoradiation. Malignant cells disobey