Tag Archives: patients

Revised Baux score and updated Charlson comorbidity index associated with mortality in burn patients

A severe burn injury induces significant systemic physiological imbalances. This may lead to subsequent complications, organ failure and death. In the United Kingdom, severe burn injuries (covering at least 15% of total body) leading to substantial hospitalisation

Kidney angiotensinogen as a cardinal risk factor in hypertension

High blood pressure is prevalent in over 30% of the adult population and accounts for approximately one fourth of patients with heart failure, especially the elderly. The renin-angiotensin system (RAS) is of critical importance in the regulation

Association of polymorphism gene with clinical variability in cystic fibrosis patients

Cystic fibrosis (CF) is an inherited disease, caused by a dysfunction (mutation) in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. This disease affects a numerous organs particularly the lungs and digestive system. CF is characterized by

Two essential cardiac disorders improvement in patients with hypertrophic cardiomyopathy

Sudden cardiac death and heart failure are the most serious complications of hypertrophic cardiomyopathy ( HCM ). To prevent these serious complications, 2 essential cardiac disorders in patients with HCM must be corrected. These are left ventricular (LV)

A functional immune system against cancer in breast cancer patients

One of the hallmarks of cancer development is the ability of tumor cells to evade the recognition by the host immune system. However, the presence of immune responses against cancer is frequently observed in cancer patients. The

Recharged autologous stem cells to combat cartilage defects in osteoarthritic patients

Inflammation is one of the greatest challenges for physicians and researchers working to find new strategies to regenerate patients’ damaged and deteriorated cartilage. Although humans have stem cells which can aid in many tissue repair processes throughout

An important new tool to assess chemotherapy response in cancer patients

Although chemotherapy agents are widely used in the treatment of cancer, it is not widely known that for many patients with solid tumours, only a fraction receive a survival benefit from chemotherapy.  This is particularly the case

Pre-radiation lymphocyte harvesting and post-radiation reinfusion in patients with newly diagnosed high grade gliomas

In people diagnosed with malignant brain tumors, the prescribed treatment is often radiation and chemotherapy; however, these treatments severely affect the immune system, increasing the chance of early death. Radiation in particular has been known to cause

The infusion of haematopoietic stem cells in patients with liver insufficiency

Cirrhosis, the end result of long-term liver damage, and its related morbidity represnt a significant burden on health care worldwide. Liver transplantation is the only definitive therapeutic option for those patients. However, the paucity of donors, the incidence

Core predictors of ‘hassles’ among patients with multimorbidity in primary care

A major problem in current primary care is that services are set up for single long term conditions, whereas many older patients have more than one.  Studies conducted through interviews only suggest that patients experience ‘hassles’ in

Leukemia cells rely on vesicles from neighboring stromal cells to resist common cancer treatments

Leukemia is a cancer of white blood cells that occurs in both children and adults.  Strides have been made in curing most types of leukemia.  However, acute myeloid leukemia (AML) continues to resist the same treatment strategies. 

CD64 as a sepsis marker

Sepsis is the most common cause of mortality in critically ill patients worldwide. Despite with huge costs, it is difficult to treat sepsis. Early diagnosis sepsis and timely treatment are vital to improving outcomes and lightening the

Obesity protects inflamed dialysis patients

A high body mass index (BMI) is linked to longer survival terms for several serious chronic debilitating diseases. A large European epidemiological study shows that this protective effect does not apply to all patients with a high

Posterior cervical fusion may lessen spinal cord compression in patients with rheumatoid arthritis

Patients with rheumatoid arthritis may develop inflammation of the joints in the spine, just as they develop inflammation of joints in their hands, feet, and others. The joint between the first cervical vertebra (C1) and the second

Surgery for pancreatic head cancer

Pancreaticoduodenectomy (PD) offers the only chance of long-term survival for patients with pancreatic head cancer. The procedure involves removing the pancreatic head together with the duodenum, gallbladder and most of the common extra hepatic bile duct (Fig.

A novel radionuclide treatment for hormone refractory metastatic prostate cancer

Prostate cancer is the second most common male cancer worldwide and the fourth most common cancer overall. In patients with localized prostate cancer, the five-year survival rate approximates to 100%; however, in patients with distant metastases, it