Tag Archives: patients

A functional immune system against cancer in breast cancer patients

One of the hallmarks of cancer development is the ability of tumor cells to evade the recognition by the host immune system. However, the presence of immune responses against cancer is frequently observed in cancer patients. The

Recharged autologous stem cells to combat cartilage defects in osteoarthritic patients

Inflammation is one of the greatest challenges for physicians and researchers working to find new strategies to regenerate patients’ damaged and deteriorated cartilage. Although humans have stem cells which can aid in many tissue repair processes throughout

An important new tool to assess chemotherapy response in cancer patients

Although chemotherapy agents are widely used in the treatment of cancer, it is not widely known that for many patients with solid tumours, only a fraction receive a survival benefit from chemotherapy.  This is particularly the case

Pre-radiation lymphocyte harvesting and post-radiation reinfusion in patients with newly diagnosed high grade gliomas

In people diagnosed with malignant brain tumors, the prescribed treatment is often radiation and chemotherapy; however, these treatments severely affect the immune system, increasing the chance of early death. Radiation in particular has been known to cause

The infusion of haematopoietic stem cells in patients with liver insufficiency

Cirrhosis, the end result of long-term liver damage, and its related morbidity represnt a significant burden on health care worldwide. Liver transplantation is the only definitive therapeutic option for those patients. However, the paucity of donors, the incidence

Core predictors of ‘hassles’ among patients with multimorbidity in primary care

A major problem in current primary care is that services are set up for single long term conditions, whereas many older patients have more than one.  Studies conducted through interviews only suggest that patients experience ‘hassles’ in

Leukemia cells rely on vesicles from neighboring stromal cells to resist common cancer treatments

Leukemia is a cancer of white blood cells that occurs in both children and adults.  Strides have been made in curing most types of leukemia.  However, acute myeloid leukemia (AML) continues to resist the same treatment strategies. 

CD64 as a sepsis marker

Sepsis is the most common cause of mortality in critically ill patients worldwide. Despite with huge costs, it is difficult to treat sepsis. Early diagnosis sepsis and timely treatment are vital to improving outcomes and lightening the

Obesity protects inflamed dialysis patients

A high body mass index (BMI) is linked to longer survival terms for several serious chronic debilitating diseases. A large European epidemiological study shows that this protective effect does not apply to all patients with a high

Posterior cervical fusion may lessen spinal cord compression in patients with rheumatoid arthritis

Patients with rheumatoid arthritis may develop inflammation of the joints in the spine, just as they develop inflammation of joints in their hands, feet, and others. The joint between the first cervical vertebra (C1) and the second

Surgery for pancreatic head cancer

Pancreaticoduodenectomy (PD) offers the only chance of long-term survival for patients with pancreatic head cancer. The procedure involves removing the pancreatic head together with the duodenum, gallbladder and most of the common extra hepatic bile duct (Fig.

A novel radionuclide treatment for hormone refractory metastatic prostate cancer

Prostate cancer is the second most common male cancer worldwide and the fourth most common cancer overall. In patients with localized prostate cancer, the five-year survival rate approximates to 100%; however, in patients with distant metastases, it

Mutations in the gene DLL4 cause Adams-Oliver syndrome

Adams-Oliver syndrome (AOS) is a rare hereditary disorder that occurs in 1 in 225.000 individuals and is characterized by the presence of both scalp and limb defects. Congenital anomalies of the heart and blood vessels are also

Kidney disease dramatically affects whether patients should undergo vascular interventions

Kidney disease is a significant risk factor for poor outcomes following vascular surgery, and should be taken into consideration when evaluating patients for elective vascular interventions. Patients with kidney dysfunction who are recommended intervention by a vascular

Natural history of multiple system atrophy in USA

Multiple system atrophy (MSA) is a rare, fatal brain disorder exhibiting a combination of parkinsonism and/or cerebellar gait unsteadiness and autonomic failure. Autonomic failure, manifest as orthostatic hypotension, severe constipation and urinary incontinence or retention, as well

Nanocarrier-based antioxidant therapy: promise or delusion?

It has been well established that the damage produced by Reactive Oxygen Species (ROS), which are highly reactive molecules with an unpaired electron, plays an important role in a large number of human diseases. Because of this

How to optimize the effectiveness of anticancer therapy

Hepatocellular carcinoma (HCC) is the most common type of liver cancer. HCC is a public health problem worldwide because of its high incidence and its poor prognosis with high cancer-related mortality. In the majority of cases, patients

CRIC: studying the silent epidemic of kidney disease

Chronic kidney disease (CKD) is a public health problem affecting more than 20 million Americans, and far more worldwide. Although CKD typically begins with no noticeable symptoms, it is a progressive disease which if untreated often leads

How my physician could adapt his or her behaviors to my preferences?

Nowadays, the recommended approach in physician – patient interaction is patient – centeredness. As the name suggests, patient – centeredness implies to put the patient in the center of the consultation and to take his or her

Employment of migrant care workers by Italian families assisting older Alzheimer’s disease patients

A rising phenomenon across the European Union (EU) is the increasing presence of migrant care workers (MCWs), privately employed by families of older people in need, who take over different tasks: supervision, drug administration, support in mobility