Tag Archives: rheumatoid arthritis

Time to switch? Switching from innovator rituximab to biosimilar CT-P10 is safe and efficacious

Rituximab is a monoclonal antibody that targets the CD20 protein that is found mainly on immune cells called B lymphocytes. By removing CD20-positive B lymphocytes from the peripheral blood and bone marrow, rituximab provides effective treatment for

Long-term safety and efficacy of rituximab biosimilar CT-P10 in rheumatoid arthritis

Rituximab is a monoclonal antibody used to treat certain cancers of the blood, as well as immune-mediated diseases such as rheumatoid arthritis. But while rituximab is effective, it is also expensive, which means that not everyone who

Coffee for the relief of symptoms of methotrexate intolerance among patients with rheumatoid arthritis

Patients with rheumatoid arthritis (RA) and some of the other systemic autoimmune rheumatic diseases are commonly prescribed methotrexate (MTX) at the dose of < 25-30 mg/week. Depending upon the patient’s condition and the dosage prescribed, some patients

Gut microbiota: A potential trigger of rheumatoid arthritis

Rheumatoid arthritis (RA) is a chronic systemic inflammatory disorder characterized by synovitis in multiple joints and systemic comorbidities. Both genetic and environmental agents are thought to be the risk factors for arthritis. Recent studies have suggested that

Current treatment for rheumatoid arthritis fails to improve patient’s body composition or physical function

Adverse changes in body composition – specifically, reduced muscle mass (MM) and increased fat mass (FM) – are characteristic of rheumatoid arthritis (RA).  Indeed, when body composition is assessed, significant muscle loss is evident in ~67% and

The price of escalating drug dose to treat rheumatoid arthritis

Rheumatoid arthritis (RA) with its characteristic joint swelling, inflammation, pain and stiffness, may be treated with biologic disease-modifying drugs. One class of drug belonging to this group inhibits tumor necrosis factor (TNF), which plays an important role

Can Radon radiation become a source of treatment for Rheumatoid Arthritis?

Rheumatoid arthritis (RA) is the most common type of autoimmune disease. It is triggered by a faulty immune system of the body. However, the real cause of the disease is not completely known. The disease affects the

Clinical studies ask: “Are less expensive ‘biosimilar’ drugs as effective and safe as current drugs?”

Several debilitating diseases caused by disorders in a patient’s immune system – often called ‘immune-mediated diseases’ – have become easier to treat in the last two decades following the discovery of drugs called ‘biologics’. Biologics act on

The undiagnosed, untreated key to restoring physical function and health in rheumatoid arthritis patients

Rheumatoid arthritis (RA) is characterised by adverse changes in body composition – specifically, reduced muscle mass (MM) and increased fat mass (FM). Indeed, when body composition is assessed (i.e. MM and FM are estimated), significant muscle loss