Tag Archives: skin

Horny skin layer enhances the skin barrier function and water bonding with increasing age

Human skin consist of three layers – epidermis, dermis and subcutaneous tissue. The main age–related changes in the skin are well investigated for the dermis and include the delay of bio fluids’ microcirculation, reduced synthesis of extracellular

What response of skin blood flow in hindlimb does electrical stimulation of forelimb induce?

The nervous system includes the central nervous system (CNS) and autonomic nervous system (ANS). Abundant evidence exists to show that structures and functions of the CNS in humans are bilaterally asymmetrical. The best known example of brain

Treating white spots of vitiligo

Skin color is such a critical part of our sense of who we are. Skin color varies from dark brown to pale white. Our skin color defines our “tribe”, that group of people with whom we identify

When your medication backfires and calls in the wolves

Your immune system is like an army inside your body. It is constantly on guard to protect you against attacks from the outside, such as infections. It also protects you from attacks from inside, such as cancer

Screening sunscreens: protecting the biomechanical barrier of skin from ultraviolet radiation damage

The uppermost layer of human skin, known as the stratum corneum (SC), is the most important physical barrier between the human body and the environment and plays a surprisingly acute role in the mechanical function of full

Perlecan HS produces TGF-β1 deficiency in mutant skin

The skin is the largest organ in the human body and one of it’s most dynamic. Skin has a large surface area and protects the body from the external environment and is challenged by many poisonous substances

Penetration ability of caffeine and propylene glycol in the skin

The stratum corneum (SC) is the uppermost layer of the skin, which provides an efficient barrier function. This barrier is always an obstacle for cosmetic formulations or medical ointments applied to the skin. The permeation through the

Keeping Score: dermoscopy for the diagnosis of melanocytic lesions

Among people at high risk for melanoma, skin cancer screening is valuable for early detection of a new malignant melanoma. When dermatologists identify a suspicious lesion, a biopsy is performed and the removed skin sample is sent

Effectiveness of an Internet intervention to decrease young adults’ risk for skin cancer

Every year, almost five million Americans are diagnosed with skin cancer. Though many think of cancer as being an issue for older people, melanoma is the second most diagnosed cancer in adults aged 20-39. This is in

Psoriasis, more than a skin disease? The involvement of gut microbes

Psoriasis, is a chronic inflammatory skin disease with a high prevalence, of which the exact cause is unknown. Genetic, immunologic and environmental factors all are involved. Psoriasis and Inflammatory Bowel Disease, including Crohn’s Disease and Ulcerative Colitis,

Microbes paralyze immune system

About every fourth child is suffering from atopic dermatitis (AD) (often called atopic eczema) and adults are also often affected by this disease. The skin of AD patients is strongly damaged (Fig. 1). It is dry, itchy,

A mild form of dermatomyositis as a prodromal sign of lung cancer: looking behind the skin

Dermatomyositis is a rare inflammatory disease characterized by specific skin findings and inflammatory lesions in the muscle biopsy. The most common clinical signs of dermatomyositis include an erythema over the face, neck and upper trunk known as

Infrared does more good than bad for the skin: how can we learn from the sun

In the last decade, it has been proposed that the sun’s Infrared (IR) wavelengths might be damaging human skin and that sunscreens, in addition to their desired effect to protect against Ultraviolet (UV), should also protect against

Evaluating methods for detecting deadly skin cancers

Melanoma is a rare, but potentially deadly, type of skin cancer that develops in skin cells called melanocytes, which are responsible for producing the pigment in your skin. According to the American Cancer Society, the probability of

Assessment of the influence of traffic-related particles in dust

Dust particles present in our daily lives consist of a mixture of materials from different sources, such as soils, traffic-related particles, pavement particles, etc. Due to their low particle size, dust particles can be easily re-suspended and

Comparing skin research funding with skin disease burden

Distributing funding dollars to research is an important and daunting task. While many factors influence research-funding decisions, establishing a transparent, priority-setting system is paramount. This is particularly important for the National Institutes of Health, which invests over