Tag Archives: stem cells

Bioengineered human pyloric sphincters with functional muscle and nerves

The gastrointestinal (GI) tract is a hollow tube that primarily functions to mediate the digestion of the food that we eat into forms of energy and nutrients that the cells and our body can use. The appropriate

Demyelination and remyelination signalling in multiple sclerosis as an aid to targeted therapy

Multiple sclerosis (MS) is an inflammatory autoimmune disease of the central nervous system (CNS) characterised by demyelination. Demyelination, i.e. damage and erosion of the myelin sheath which protects the nerve fibres, occurs in the white matter of

Contraception protects females against germline tumours… in worms

Genetic females of the nematode worm C. elegans initially produce 30-40 oocytes that accumulate in two U-shaped gonad arms, after which oocyte production ceases until a male is encountered. Oocyte accumulation is perceived as a signal that

Bone marrow transplantation resets the clock in patients with Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia (CLL) accounts for about one third of all of leukemias. In the United States 15,000 patients are diagnosed with and 4,500 patients die of CLL every year.  CLL is a diverse disease. Some patients

Recharged autologous stem cells to combat cartilage defects in osteoarthritic patients

Inflammation is one of the greatest challenges for physicians and researchers working to find new strategies to regenerate patients’ damaged and deteriorated cartilage. Although humans have stem cells which can aid in many tissue repair processes throughout

Stem cell therapy for Parkinson’s disease

Parkinson’s disease is one of the most common neurodegenerative diseases of the central nervous system. Its main symptoms are motor disturbances such as tremors, rigidity and slowing of movements; although patients may also suffer from sleep disorders,

How to know transcription factors by the company they keep

The ENCODE project is a massive data-collection effort set out to understand the function of the human genome. The collection comprises many types of genomic data, including the localization of transcription factors onto DNA. Transcription factors are

The infusion of haematopoietic stem cells in patients with liver insufficiency

Cirrhosis, the end result of long-term liver damage, and its related morbidity represnt a significant burden on health care worldwide. Liver transplantation is the only definitive therapeutic option for those patients. However, the paucity of donors, the incidence

Using stem cells to battle brain diseases

Neurodegenerative diseases are conditions resulting from the malfunction and death of brain cells, known as “neurons”. As people are living longer, neurodegenerative diseases affect an increasing number of people and pose a major social and economic burden