Tag Archives: stress

Reducing cellular stress may prevent diabetes complications

Poorly controlled diabetes is often associated with various complications including blindness, kidney failure and pain secondary to damaged nerves. However, the most common complications are those related to large blood vessel disease such as heart attacks and

Stress must not be confused with pain

Our article “Stress is not pain” was a critique on a study by Elwood & Adams who exposed crabs to electric shocks and concluded that their study ‘. . .fulfils the criteria expected of a pain experience’. 

Is personality related to biological stress reactivity?

In his influential biopsychological theory of personality, Hans J. Eysenck proposed in 1967 that there was a biological basis to personality. He described two main personality traits which could be measured on a continuum. Individuals scoring high

How does exercise reduce the intake and preference for high fat, high sugar foods?

People gain weight because they eat too much food, particularly food with a lot of fats and sugars, and do not use the calories gained from food. In this case the energy intake is higher than energy

Acyl-CoA-binding proteins help plants “degrease” adversities

Serving as the building blocks for triacylglycerides and membrane phospholipids, fatty acids are essential in all forms of life. Given their chemical inertness, fatty acids need activation into a more water-soluble form (as acyl-CoA esters), prior to

Stress hormone level shoots up during abiotic stress to sustains the stress in S. quadricauda

Energy is an inevitable part and makes life possible.  Globally, over 90 percent of transportation energy requirement is met by fossil fuels. International Energy Agency (IEA) predicts that, if we continue to use the fossil fuel at

Phospholipase C break membrane lipids during plant adaptation under stress

Plants constantly encounter various biotic and abiotic stresses in the environment. These stresses present adverse growth conditions, which affect the plant development, longevity and productivity. The crop production is decreasing rapidly due to the negative impact of

Application of the fungicide kresoxim-methyl prior to drought and salinity stress imposition enhances the ability of plants to survive

Plants are exposed to multiple environmental stresses ( e. g. drought, salinity ), resulting in major yield losses in modern agriculture. Drought and salinity are the two major abiotic threats for plant production and potentially food security.

Stressful childhoods lead to shorter adult height, but via different pathways for boys and girls

As children grow into adults, they face compromises between prolonging growth, and reaching milestones such as puberty and the start of reproduction. They respond to cues in their environment in order to choose the best compromise. In

A transcriptomic approach for cardiac (heart) safety assessment

New drug discovery relies on several phases of safety assessment. One such prominent in vitro safety assessment assay is the “hERG potassium channel assay” for cardiac safety. If a compound blocks the hERG potassium channel in a

Good morning… let the stress begin. What is stress and how do we study it?

The American Psychological Association estimates that more than 70% of Americans regularly experience the physiological or psychological symptoms associated with chronic stress, with a third of the population thought to be living with extreme levels of stress.

Cushing’s Syndrome: an update on current pharmacotherapy and future directions

Cortisol is an adrenal hormone essential for the maintenance of homeostasis, especially in response to stress. When cortisol levels are increased, this is defined as Cushing’s syndrome (CS). CS can be associated with increased morbidity, and when

Hormetic use of stress in gerontological interventions requires a cautious approach

Hormesis is a biphasic dose-response pattern in which the response at low doses is opposite to that at higher doses. According to the hormesis concept, a small dose of a potentially harmful agent can exert a beneficial

Cortisol levels as index for vulnerability to stress

Stress exposure is known to precipitate psychological disorders. However, large differences exist in how individuals respond to stress; whereas some people thrive under stressful situations, others break down and are at risk to develop psychopathology. One important

What predicts who will do well in treatment for post-traumatic stress disorder?

Post-traumatic stress disorder (PTSD) is a common psychological response following a traumatic event and affects about 8% of the population. Effective psychological treatments do exist and should be made available to anyone who is diagnosed with PTSD.

With a little help from friends: how plastids aid the ER to deal with misfolded proteins

Almost a third of all proteins in eukaryotic cells are synthesized and folded in the endoplasmic reticulum (ER) before being secreted and redistributed to other organelles, such as the Golgi apparatus, lysosomes, and the plasma membrane. To