Tag Archives: stress

Growing-up in a stressful environment affects the levels of glutamate in the hippocampus in adult depresses subjects

Mood disorders are emotional disturbances consisting of prolonged periods of excessive sadness, excessive joyousness, or both. Exposure to harsh parenting practices or to maltreatment during childhood can increase individuals’ vulnerability to mood disorders and the severity of

Decreased vagally-mediated heart rate variability in a conditional NPY Y1 receptor knockout mouse

Neuropeptide Y (NPY) is a protein involved in the complex regulation of a variety of physiological functions that range from feeding to emotions. In the central nervous system NPY is able to influence autonomic nervous system regulation

Does subjecting health students to stressful scenarios better prepare them for real world practice?

Simulation is an education and training technique that allows students to practice in safe environments that replicate substantial aspects of the real world in a fully interactive fashion.  Simulation is often used to train undergraduates as it

Stress and pain – subgroups, mechanisms and treatment outcomes

Chronic pain affects 100 million US adults and with costs exceeding $500 billion per year. Fibromyalgia (FM) is a prevalent chronic pain disorder characterized by widespread pain, fatigue, anxiety and depression, and problems with memory and concentration.

Reducing cellular stress may prevent diabetes complications

Poorly controlled diabetes is often associated with various complications including blindness, kidney failure and pain secondary to damaged nerves. However, the most common complications are those related to large blood vessel disease such as heart attacks and

Stress must not be confused with pain

Our article “Stress is not pain” was a critique on a study by Elwood & Adams who exposed crabs to electric shocks and concluded that their study ‘. . .fulfils the criteria expected of a pain experience’. 

Is personality related to biological stress reactivity?

In his influential biopsychological theory of personality, Hans J. Eysenck proposed in 1967 that there was a biological basis to personality. He described two main personality traits which could be measured on a continuum. Individuals scoring high

How does exercise reduce the intake and preference for high fat, high sugar foods?

People gain weight because they eat too much food, particularly food with a lot of fats and sugars, and do not use the calories gained from food. In this case the energy intake is higher than energy

Acyl-CoA-binding proteins help plants “degrease” adversities

Serving as the building blocks for triacylglycerides and membrane phospholipids, fatty acids are essential in all forms of life. Given their chemical inertness, fatty acids need activation into a more water-soluble form (as acyl-CoA esters), prior to

Stress hormone level shoots up during abiotic stress to sustains the stress in S. quadricauda

Energy is an inevitable part and makes life possible.  Globally, over 90 percent of transportation energy requirement is met by fossil fuels. International Energy Agency (IEA) predicts that, if we continue to use the fossil fuel at

Phospholipase C break membrane lipids during plant adaptation under stress

Plants constantly encounter various biotic and abiotic stresses in the environment. These stresses present adverse growth conditions, which affect the plant development, longevity and productivity. The crop production is decreasing rapidly due to the negative impact of

Application of the fungicide kresoxim-methyl prior to drought and salinity stress imposition enhances the ability of plants to survive

Plants are exposed to multiple environmental stresses ( e. g. drought, salinity ), resulting in major yield losses in modern agriculture. Drought and salinity are the two major abiotic threats for plant production and potentially food security.

Stressful childhoods lead to shorter adult height, but via different pathways for boys and girls

As children grow into adults, they face compromises between prolonging growth, and reaching milestones such as puberty and the start of reproduction. They respond to cues in their environment in order to choose the best compromise. In

A transcriptomic approach for cardiac (heart) safety assessment

New drug discovery relies on several phases of safety assessment. One such prominent in vitro safety assessment assay is the “hERG potassium channel assay” for cardiac safety. If a compound blocks the hERG potassium channel in a

Good morning… let the stress begin. What is stress and how do we study it?

The American Psychological Association estimates that more than 70% of Americans regularly experience the physiological or psychological symptoms associated with chronic stress, with a third of the population thought to be living with extreme levels of stress.

Cushing’s Syndrome: an update on current pharmacotherapy and future directions

Cortisol is an adrenal hormone essential for the maintenance of homeostasis, especially in response to stress. When cortisol levels are increased, this is defined as Cushing’s syndrome (CS). CS can be associated with increased morbidity, and when