Tag Archives: Survival

“Agene”: Using age and mutation status to accurately predict survival outcome in patients with primary myelofirborsis

Primary myelofibrosis (PMF) is a rare form of cancer of the bone marrow in which abnormal proliferation of blood-producing cells result in replacement of the marrow with a scar tissue (“fibrosis”). The course of PMF is variable.

The distressful life of FtsZ-deprived bacteria

Failure to assemble a division septum occurs in Escherichia coli cells when their supply of FtsZ is blocked. FtsZ, ancestor of eukaryotic Tubulin, is the main component of the divisome, the molecular machinery that drives septation in

The importance of clinical endpoints in lymphoma

Lymphomas, or neoplasms of the lymphoid system, include a broad array of cancers. The least aggressive, often called indolent, lymphomas (the most frequent of which is follicular lymphoma, FL) are characterized by their incurability. At the same

Positron Emission Tomography can visualize pancreatic cancer tumor changes during chemotherapy and predict longer survival

Pancreatic cancer is one of the most deadly cancer types. Only 20% of patients live beyond 1 year after diagnosis because of the aggressive nature of this disease and ineffective treatments. Therefore it is crucial to recognize

Less is more for staging vaginal cancer

Criteria for predicting the survival of women with vaginal cancer has been established by physician specialists trained in treating gynecologic cancers in the United States and around the world. The current 5-year overall survival is approximately 74%

Survival analysis using Excel: learn it, use it and improve your work

Questions about disease prognosis and patient survival are of central importance in everyday hematology/oncology clinical practice. If a person working as a practicing clinician would like to evaluate his/her own work or check if some factor affects

The molecular analysis of tumor cells in pancreatic tissue – searching for a needle in a haystack

In cancer research usually the tumor cell specific abnormalities are of interest: gene mutations, production of abnormal proteins, production of abnormal quantity of proteins, tumor cells treatment response. But the molecular analysis of pancreatic tumor samples poses

Major amputation in the management of advanced limb melanoma

Melanoma is an aggressive type of skin cancer that can recur at the original excision site or spread to nearby areas of the body (called “in-transit” metastases), to the lymph nodes that drain that region and/or to

Comparison of biological and cultural evolution

Biological evolution is a population-level process guided by selection, and it leads to an increase of the adaptation of the population for the environmental circumstances in which the population lives. Culture can be defined as the wholeness of

Delaying surgery for IBD patients may have grave consequences

When discussing a proposed therapy for any illness, patients undoubtedly, and understandably, want to know the side effects. This includes the most serious side effect – the risk of death. The Inflammatory Bowel Diseases (IBD), comprised of

The risk of death from high-risk prostate cancer in men undergoing EBRT and brachytherapy

According to the National Comprehensive Cancer Network (NCCN) guidelines, treatment with long-course (28–36 months) androgen deprivation therapy (ADT), in addition to brachytherapy (where radioactive seeds are implanted inside the prostate to kill cancer cells) and external beam radiation