Tag Archives: therapy

Discovery of Bag3-P209L signaling mechanism brings hope for therapeutic options currently in development

Myofibrillar myopathy (MFM) is a group of rare genetic disorders that cause both skeletal and cardiac muscle weakness. Mutations in the Bcl2-associated Athanogene 3 (Bag3) protein, highly expressed in striated muscle, are reported to cause a particularly

Annual Summit on Cell Signaling and Cancer Therapy. Chicago, USA. September 27-28, 2017

Annual Summit on Cell Signaling and Cancer Therapy is bustling to be held at Chicago, USA during September 27-28, 2017 hosted by Conferences Series. Through the theme “To Frame An Admiring Portal For Pioneering Cancer Therapy and

Radiation-induced morphea: an under-recognized complication of breast radiation

Worldwide, breast cancer was the most common new diagnosis and common cause of death in women in 2012. As screening for breast cancer has improved patients are often identified in the early stage of disease and are

ACT for a “self” relieved of the burden of pain

Chronic pain is often defined as any pain lasting more than 3 months, and may arise from an initial injury, an on-going illness, or no clear cause. The change and suffering wrought from chronic pain could fundamentally

Novel approaches to cancer treatment encoded within non-coding RNA

A hallmark of all living organisms is the presence of genetic material within each cell; this material is invariantly composed of a specific class of biological molecules known as the nucleic acids. While the more familiar variety

A New therapy for healing nonunion fractures in patients using self-bone marrow derived mesenchymal

Sometimes a broken bone fail to heal (“nonunion”) and it is necessary to induce the formation of new bone tissue to connect the broken pieces. Investigators from the Instituto Venezolano de Investigaciones Cientificas (IVIC) and orthopedic surgeons

An international team opens new avenues toward PKU therapy

When a baby is born, a simple blood test reveals whether the child has PKU, which is a recessive genetic disorder where the body fails to regulate the amount of phenylalanine (Phe) in blood.  Phe is a

Nonadherence to immunosuppressive therapy in kidney transplant recipients

End-stage kidney disease (ESKD) is an increasing worldwide illness that compels patients to accept either dialysis or kidney transplantation that is the best choice because ensures high quality of life. But, living or cadaveric kidney donation is

Nutritional therapy may slow down cirrhosis

One in 400 citizens of western industrialized countries suffers from chronic liver disease or its end-stage, liver cirrhosis. The only definite cure for this is a liver transplant, but the scarcity of organs and required immunosuppression render

Fluorescent carbon dots integrated hydrogels for lung cancer therapy

Cancer is considered as one of the leading cause of death worldwide. Due to the ever changing lifestyle of the modern society, the incidence of cancer is on the rise. Lung cancer is the most frequently diagnosed

The key key to open the door of iPSCs clinical therapy for patients

The discovery of iPSCs is probably one of the most astonishing accomplishments in the beginning of 21st century. This is by 4 early protein factors, the differentiated cells–such as fibroblasts, T and B cells—can return to pluripotent

Prompt resolution of essential drug intolerance

The gut is nowadays seen as a site of cross-talk and interchange between the inner body (supposed to be sterile, namely free of viable harmful bugs) and the outer contaminated world, mainly entering the digestive tract through

Improving nature’s own communication system to fight cancer

Our bodies are composed of trillions of different cells, which communicate with each other in order to keep us healthy. There are several ways in which messages can be sent back and forth between cells. One of

Screening breast MRI in patients with personal history of breast cancer

This study looked at patients who had a personal history of breast cancer diagnosed at a premenopausal age to see if having screening breast MRI provided a benefit to the patient. Patients with a personal history of

Three dimensional quality assurance protocol for thoracic and genitourinary radiation therapy

After cancer diagnosis one treatment option is the use of external radiation. As the radiation traverses the patient it deposits most of its energy in the tumor, which causes irreparable damage to the cancer cells. One type

A brain haemorrhage during anticoagulant therapy: what therapy next?

We read with interest the articles by Ntaios and by Ricci et al. concerning pros and cons of restarting oral anticoagulants (drugs that work to prevent the coagulation (clotting) of blood) after intracerebral hemorrhage. While we appreciate