Tag Archives: tumor

Is our immune system mistaking tumours for foetuses?

Tumours are abnormal growths of tissue where cells produced by the body get out of control and divide at a rapid and unregulated pace. And – when you think about it – embryos too are masses of

Improving nature’s own communication system to fight cancer

Our bodies are composed of trillions of different cells, which communicate with each other in order to keep us healthy. There are several ways in which messages can be sent back and forth between cells. One of

Heat shock protein as a novel druggable target in angiogenesis?

Angiogenesis is a physiological process that involves formation of new blood vessels from pre-existing vessels for efficiently providing oxygen and nutrients during growth and development, as well as during wound healing. Under pathological conditions, angiogenesis is regulated

Treatment holidays for patients with metastatic kidney cancer

Targeted therapy is the standard treatment of patients with metastatic cancer of the kidney. The best current therapies target the tumour vasculature thereby blocking the access of the tumour to nutrients and limiting possibility of spreading to

Emergency department presentation predicts poor outcomes after meningioma removal

A meningioma is one of the most common forms of a brain tumor. Unlike many other types of brain tumors, meningiomas are typically associated with relatively favorable outcomes even when they require surgical treatment. In the past

Another prince awakened Sleeping Beauty?

Tumor suppressor genes are one of the body’s defenses against uncontrolled growth of tumor cells. When these genes are ‘silenced,’ or prevented from doing their work, the abnormal cells grow unchecked, usually with fatal consequences to the

Routine brain MRIs may not be needed after meningioma surgery

A meningioma is a very common form of a brain tumor that tends to affect elderly patients and women. Most patients with meningiomas do not need any treatment, however, certain groups undergo surgical removal of the tumor.

The right tool for the right job – it is brain surgery after all!

Getting drugs into the brain to help treat cancer or neurological diseases like Parkinson’s or Alzheimer’s is pretty difficult. Generally speaking you can’t just take a pill or get an injection as the brain is protected by

Radiotherapy for prostate cancer: restrictions for the treatment of recurrent disease

Patients with prostate cancer who are treated with radiotherapy are not always cured. Depending on their pre-treatment risk factors (most importantly the stage of the tumour), they are at risk of recurrent disease. These recurrences often present

Defeating cancer by taking advantage of its inbuilt frailties

The treatment of cancer is a conflicting and complex process; the drugs that are used to kill cancer cells are also toxic to your healthy tissues. However, the different physiology of tumors provides a route to deliver

Milk exosomes for drug delivery

The need to effectively deliver drugs to target site has employed a multitude of substances varying from biological to a chemical nature and solid metals for the preparation of tiny drug delivery vesicles called nanoparticles. However, factors

Side effects of radiation therapy: Why me?

Most lung cancers are treated with radiation therapy, often in high doses.  Although these treatments are absolutely required to prolong life (by killing the tumor or slowing its growth), radiation treatment can have negative side effects that

Importance of updating prognostic predictions: an example from breast cancer

Today prognostic prediction models are an integral part of clinical practice in many fields. They are typically used to access the risk of an event in the future after a well-defined starting point, for instance the risk

The many faces of macrophages in lung cancer

Lung cancer is the leading cause of cancer death worldwide, accounting for more deaths than breast, prostate, and colon cancer combined. Within the past decade, the role of the immune system in the development and progression of

The molecular analysis of tumor cells in pancreatic tissue – searching for a needle in a haystack

In cancer research usually the tumor cell specific abnormalities are of interest: gene mutations, production of abnormal proteins, production of abnormal quantity of proteins, tumor cells treatment response. But the molecular analysis of pancreatic tumor samples poses

Combinatorial cancer therapies: too many “good guys” don’t do always good!

“Μέτρον άριστον” (Metron ariston) is an ancient Greek phrase, attribute to Cleobulus (6th century BC), one of the Seven Sages of Antiquity, and is translated, as “Moderation is the best”. This was meant to be applied to