Crowd surfing of graphene on a lipid monolayer

Crowd surfing of graphene on a lipid monolayer

In the recent years a growing interest in graphene applications lead to the development of new biosensor devices More »

Diving into cell membranes with advanced solid-state NMR methods

Diving into cell membranes with advanced solid-state NMR methods

Membrane proteins act as the gateways of the cell. They are essential for the signalling between cells and for the uptake of nutrients More »

Gene duplication catalyzes the evolution of new traits in a human pathogen

Gene duplication catalyzes the evolution of new traits in a human pathogen

How do organisms with common ancestry evolve unique traits and eventually diverge from each other? More »

Genes on or off! How regulatory DNA variations disrupt the balance of P53 and cMYC binding

Genes on or off! How regulatory DNA variations disrupt the balance of P53 and cMYC binding

Identification of causative DNA variants in common complex diseases is very important to screen individuals with high-risk for diseases More »

 

More Paleolithic-like lifestyles and diets associated with lower colorectal cancer risk

More Paleolithic-like lifestyles and diets associated with lower colorectal cancer risk. Atlas of Science

Colorectal cancer (CRC) is the second leading cause of cancer deaths among women and men combined in the United States. CRC incidence (i.e., the rate of new diagnoses) varies about 20-fold across countries. The incidence among immigrants

What happens inside the eye: fluid forces under physiologic movements

What happens inside the eye. AoS

The vitreous is a gel-like structure that completely fills the posterior part of the eye. Doctors inject drugs directly inside the vitreous to cure sight-threatening diseases like age-related macular degeneration. These are relatively new therapies; few is

High potential polymer carriers to enhance antibiotic efficiency in bacterial biofilms

Cystic fibrosis (CF) is a frequent genetic disease resulting in chronic and difficult-to-treat pulmonary infections and inflammation that needs a lifelong treatment with aggressive antibiotic therapy by oral, intravenous or inhaled routes. The most abundant bacterial species

Associations between mathematics development and visuo-spatial perception in children with cerebral palsy

Computerized rotation task. AoS

Previous research has suggested that children with cerebral palsy (CP) have difficulties with visuo-spatial perception. We wanted to find out if there was an association or relationship between the children’s visuo-spatial abilities and the development of their

Complexity and behavioral diversity in evolving populations under uncertainty

Complexity and behavioral diversity in evolving populations. AoS

Evolutionary Game Theory – an application of game theory to evolving populations in biology, introduced by Maynard Smith and Price in 1973 – provides a mathematical framework describing dynamics of competition and strategic behavior according to Darwinian

3D-printed chitosan scaffolds for the improved in-vivo wound healing in diabetic rats

In the tissue engineering context, fabrication of porous three dimensional (3D) printed chitosan (CH) scaffolds for skin tissue regeneration and their behavior in terms of biocompatibility, cytocompatibility and toxicity toward human fibroblast (Nhdf) and keratinocyte (HaCaT), was

Stable housing can significantly improve health outcomes in women living with HIV

Positive effect of stable housing on viral suppression and CD4 cell count in women living with HIV. AoS

Unstable housing, including homelessness, is a key socioeconomic determinant of poor health outcomes and premature death in the United States. Housing-insecure individuals are more likely to delay seeking medical care due to costs, lack of health insurance,

Circulating fibrocytes as possible new target of abatacept effect in systemic sclerosis patients

Circulating fibrocytes as possible new target. AoS

Systemic sclerosis (SSc) is an autoimmune connective tissue disease characterized by microvascular and immune response alterations followed by a progressive fibrosis, which is the consequence of an excessive production and deposition of extracellular matrix molecules, primarily fibronectin

Prefrontal-auditory communication in fear discrimination

Identifying neural networks that infer safety versus danger is of great interest in the scientific field. Fear generalization reduces the chances of an animal’s survival and leads to psychiatric diseases, such as post-traumatic stress disorders and phobias

Parasite control – breaking the worm cycle

Gastrointestinal parasites are a major health challenge for all grazing animals, whether they are located on paddocks and rangelands (such as horses, sheep cattle or goats) or in zoos (such as giraffe and zebra). In a previous

kINPen09 plasma treatment leads to antimicrobial effects against Candida albicans biofilms

Fluorescence microscopy of plasma-treated biofilms. AoS

Microbial communities are an increasing problem in medicine but also in industry. Thus, an efficient and rapid removal of biofilms from surfaces is becoming increasingly important. With the aid of the kINPen09, a radiofrequency plasma jet (RFPJ)

Ketamine, not TPS potentiates glutamate-induced Ca neurotoxicity

Ketamine, not TPS potentiates glutamate-induced Ca neurotoxicity. AoS

There is growing concern about anaesthesia effects on the developing brain because commonly used anaesthetics can cause neurodegeneration and long-term neurocognitive deficits. In the developing brain, GABA-R agonists and NMDA-R antagonists cause neurotoxicity and apoptosis. Comparing their

Iron: it is all in the core

Iron is transported in the body using transferrin. AoS

Iron, the most abundant element on the Earth’s core, is an essential substance necessary for a number of reactions in the body which lead to the production of necessary  energy allowing optimal function. Iron deficiency (ID) and

Pulmonary arteriovenous malformations (PAVM) should be treated by embolization

Pulmonary arteriovenous malformations. AoS

Pulmonary arteriovenous malformations (PAVM) are congenital vascular communications in the lungs. They act as shunts so that the blood running through these malformations is not oxygenated or filtered (Fig. 1). These patients will typically have dyspnea on

Nanocrystalline 3D homojunctions for next generation opto-electronics

Schematics of (a) SSE of pn NHJ film for creating (b) solar or lighting device. AoS

Planar pn junctions constitute an integral part of optoelectronic devices. Inorganic semiconductor crystals offer superior properties compared to organics but high-grade crystals are expensive and difficult to produce in large volume. Bulk heterojunction (BHJ) and ordered heterojunctions

Are Baltic grey seals (Halichoerus grypus grypus) exposed to phenol derivatives?

Are Baltic grey seals. AoS

Plastics and endocrine active compounds (EDCs) reaching the sea is a very current topic. Global society is beginning to notice plastics accumulating on beaches, in coastal waters and in so-called “Great Garbage Patches” in the oceans. The

Duodenal neuroendocrine tumors: what we really know about them? An Italian multicentre experience

Duodenal Neuroendocrine Tumors. AoS

Duodenal neuroendocrine neoplasms (dNENs) are heterogeneous tumors and represent up to 3% of all duodenal tumors and 2–3% of all gastrointestinal tumors. Despite clear differences, dNENs have been always treated together with either gastric neuroendocrine tumors or,

Dynamic electron microscopy: recording of ATP-induced myosin head movement in living muscle myosin filament

Muscle contraction results from relative sliding between actin and myosin filaments, caused by cyclic movement of myosin heads coupled with ATP hydrolysis. It is generally believed that individual myosin heads M), extending from myosin filaments, first bind

Skewed signaling through RAGE strength the tumor growth-promoting activities of M2 macrophages

Skewed signaling through RAGE strength. AoS

Tumors are complex tissues composed by both non-cellular components, mainly matrix proteins, and different stromal cell types, which are under an active cross talk with tumor cells. Tumor-associated macrophages (TAMs) are the major leukocyte population among the

Urbanization facilitates migration of the human health pest, Western black widow spider

Western black widow spider. AoS

By 2050, more than half of the global human population is expected to live in urban areas. As these urban areas rapidly grow, they replace some of our most pristine habitats. One effect that urbanization has is