Atherosclerosis is a chronic medical condition characterised by the accumulation of fat in the walls of blood vessels, which obstruct the normal flow of oxygen-rich blood and can have severe health consequences. Peripheral arterial disease (PAD) is
Obesity typically occurs when a person eats more calories than they need for their daily activity. It results in a build-up of fatty tissue around all organs. In lean people, fat tissues work closely with hormones to
Rheumatoid Arthritis (RA) is a common inflammatory disease that is characterized by swelling and tenderness of multiple joints. The resulting pain and joint stiffness cause disability for patients and treatment to control the inflammation is required to
Juvenile localized scleroderma, also known as morphea, is an rare condition, it occurs around 1 in 5000 children, where the skin and the tissues underneath the skin like fat tissue, muscle, tendons, and bone, get inflamed and
Can we accurately diagnose different clinical variants of Progressive Supranuclear Palsy using IPMDS-PSP criteria?
Progressive Supranuclear Palsy (PSP) is the second most common degenerative parkinsonian syndrome after idiopathic Parkinson’s disease. PSP is a clinically heterogeneous disorder with several clinical variants. The two most common clinical variants are the Richardson (PSP-RS) and
Microbial communities (i.e. groups of potentially interacting microbial populations that co-exist in space and time) most commonly represent complex and highly diverse assortments of microbial populations, each possessing different genomic features that reflect on their specific life
The study of pattern formation has advanced to a new phase involving channel molecules acting on bioelectric signals, with gap junctions being major relevant factors. Gap junctions are composed of connexin proteins: six connexins form hemichannels/connexons on
Chagas disease (CD) is neglected tropical disease (NTD) that affects over 6 million people mainly in the poorest areas of Latin America. CD also represents a public health concern in non-endemic areas such as North America, Asia,
Waking a sleeping giant: How increasing Africa’s research output can benefit global cardiovascular health?
Africa is home to 1.4 billion people, of whom 55 million suffer from cardiovascular disease (CVD). Despite this, Africa contributes to only 1.7% of the world’s cardiovascular science. We studied 179 clinical trials led by African researchers
Since the emergence of immune checkpoint inhibitors (ICIs), cancer immunotherapy has dramatically developed. However, its drawback is the low overall response rate to its therapeutic effect. The efficacy of immunotherapy is suggested to depend on the immune
Sustainable solutions: Tamarind Seed Kernel powder (TKP) adhesive as a green alternative for lignocellulosic composites
The majority of petroleum-based adhesives applied in the wood industry today, particularly formaldehyde-based adhesives. Their application trend is increasing due to their wide availability, superior bonding, durability, and resistance to heat and moisture. However, formaldehyde-based adhesives continuously
The fulfilment of the probabilistic fatigue characterization of materials based on the S-N field requires the definition of the statistical distribution of the percentile curves of the failure probability, interpreted as a simplification, by their confidence bands.
The biopolymer starch is well-known in the kitchen for baking, cooking, and as a component of flour and is available in large quantities. This makes starch interesting as sustainable resource to convert it into biodegradable products to
If someone were to put Nature under a microscope, it would become obvious that microbes are present in all environments on our planet. Microbes are often forced to interact within proximity and share resources as an important
The answer is: it depends. Of course, there is no trivial answer to an open question like that when referring to scientific investigation. But we can make you think better before exposure to certain pesticides like malathion.
Murburn concept (from “mured burning”, signifying a restricted uncontrolled oxidative process) provides a tangible rationale why oxygen is so quintessential for immediate maintenance of life-order. It postulates that oxygen-centered diffusible reactive species (DRS, like superoxide radical) are
Comprehensive genetic analysis of glioblastomas by The Cancer Genome Atlas (TCGA) has proposed a new classification based on genetic abnormalities. The characteristic genetic abnormalities identified in the TCGA are promising candidates for novel molecularly targeted therapies, and