BioID screen for bacterial virulence proteins: new tools for infectious disease research
The discovery of penicillin in the 1920s revolutionized our ability to treat bacterial infection. However despite the introduction of antibiotics, infectious bacterial pathogens remain an immense challenge for the healthcare community. The incidence of infection by antibiotic-resistant
Layer-dependent fast electron transfer at the Zn-phthalocyanine-few-layer graphene interface: theory explains
The photo-induced effective interfacial charge separation in Zn phthalocyanine/few-layer graphene heterojunctions has been a promising observation for fabrication of efficient energy-conversion devices. Few-layer graphene are two-dimensional (2D) systems composed of one-atom-thick honeycomb layers of sp2 -hybridized carbon
Emerald Ash Borer attacks trees revealing early chemical clues
The Emerald Ash Borer (EAB), Agrilus planipennis, is a major global forest pest (a buprestid beetle) that has decimated ash trees (Fraxinus species) throughout Europe and Asia. Since this nonnative invasive insect was introduced into the U.S.
Your pharmacist will see you now!
Public perception of pharmacists might be limited to dispensing medications. However, pharmacists are trained to deliver patient care to help patients improve their health-related outcomes and achieve their goals. Recognizing the expertise of pharmacists, the State of
A mixture of plant extracts attenuates postprandial glycemia
The epidemiological studies demonstrate beneficial effects of a regular consumption of fruits, vegetables or grains on human health, which is usually a result of their lower caloric value and dietary fiber and specific bioactive compounds present in
No adverse outcomes for infants associated with mums booster of whooping cough vaccine
What is whooping cough, or pertussis? Whooping cough, or pertussis, is a highly contagious bacterial respiratory infection that can be very serious for young infants. Symptoms include violent coughing fits which can last for weeks and make
New 90-million-year-old fossil turtle discovered living alongside dinosaurs in the Zuni Basin, NM
A new fossil species of Cretaceous baenid (extinct turtle) was recently discovered from the Moreno Hill Formation in the Zuni Basin of western New Mexico. The new species, known as Edowa zuniensis (Fig. 1), is the first
Edible coating for enhancing the shelf life of horticulture products
Preserving food, especially horticulture products, is one of the most difficult farm work. The global community has highlighted this problem and set a target of halving per-capita food waste by 2030. Post-harvest losses are one of the
Optimal optoelectronic properties of MoS2/h-BN/WSe2 van der Waals heterostructures
With the development of next generation semiconductor photoelectric devices towards miniaturization, high performance and high integration, traditional bulk materials are facing enormous challenges. The discovery of graphene has opened the door to the research and application in
Can tremor, depression and progression of the Parkinson’s disease be suppressed simultaneously?
The short answer to this question is YES! Parkinson’s disease (PD) is the second most common age-related and progressive neurodegenerative disorder following Alzheimer’s disease (AD). It is associated with motor deficits such as loss of ability to
Campylobacter antimicrobial resistance in dogs and humans
Campylobacteriosis has been the most frequently reported zoonotic disease in humans in Europe since 2005, and the annual number of notified campylobacteriosis cases has increased in many European countries in recent years. The species most associated with
Turbulent flow simulation using a parallel discontinuous method
Turbulent flow is omnipresent in everyday life. When one flies in an aircraft or drives a car, the flow around the vehicle is mostly turbulent. Understanding turbulence has practical importance not only in improving passenger comfort and
Newly emerging drugs of abuse: A cat-and-mouse game
Recreational drug abuse and the resultant overdose have been a serious public health threat in the U.S. and the world. While traditional drugs of abuse remain popular, recreational use of newer synthetic drugs has continued to increase.
The allergies go marching on: the atopic march and the temporal relationship of allergic diseases
Atopic/allergic family of diseases affects >20% of the global population and encompasses allergic asthma, hay fever, food allergy, atopic dermatitis, and allergic rhinitis. Frequently, individuals with an allergic condition develop another allergic disease. The atopic march theory
The root is an ideal system to study magnetobiology in plants
Given that the origin and evolution of life had occurred in the presence of the geomagnetic field (GMF), it is possible that GMF information has been exploited by organisms as an important natural resource to tackle the
Short hydrogen bonds in proteins and their quantum mechanical nature
The assembly of linear polypeptide chains into functional three-dimensional protein architectures involves a unique force called hydrogen bonding. A typical hydrogen bond forms when the donor and acceptor groups approach each other with a nearly linear geometry
Modulation of intracellular dopamine signaling by aripiprazole may cause malocclusion as an extrapyramidal symptom
Aripiprazole, a dopamine partial agonist, is one of the most widely prescribed atypical antipsychotics and its use in children and adolescents has become common. However, due to its favorable side effect profile, its potential for inducing extrapyramidal
Role of dopamine in cortico-basal ganglia loop in psychosis
Dopamine plays a major role in the formation of acute psychosis, as indicated by the dopamine hypothesis of schizophrenia. The relationship between acute psychosis and the dopamine system provides insight into the effects of dopamine on brain
Defects in mismatch repair increase cancer risk and influence treatment selection
Microsatellites are formed by 1-6 nucleotide base pairs that are repeated in direct order 5-50 times. Repetitive DNA including microsatellites are mainly present in non-coding DNA regions that occupy more than 97% of the nuclear DNA. They
Is milk and meat from the offspring of a bull genome edited to have no horns safe to eat?
Horns on cattle are an animal welfare and human safety concern, but most high producing dairy breeds grow horns. Introducing the polled (hornless) trait into the dairy population by crossbreeding would also introduce non-productive traits by linkage