Crowd surfing of graphene on a lipid monolayer

Crowd surfing of graphene on a lipid monolayer

In the recent years a growing interest in graphene applications lead to the development of new biosensor devices More »

Diving into cell membranes with advanced solid-state NMR methods

Diving into cell membranes with advanced solid-state NMR methods

Membrane proteins act as the gateways of the cell. They are essential for the signalling between cells and for the uptake of nutrients More »

Gene duplication catalyzes the evolution of new traits in a human pathogen

Gene duplication catalyzes the evolution of new traits in a human pathogen

How do organisms with common ancestry evolve unique traits and eventually diverge from each other? More »

Genes on or off! How regulatory DNA variations disrupt the balance of P53 and cMYC binding

Genes on or off! How regulatory DNA variations disrupt the balance of P53 and cMYC binding

Identification of causative DNA variants in common complex diseases is very important to screen individuals with high-risk for diseases More »

 

Harbinger of increased prostate cancer risk: The effect of decreased prostate cancer screening

Harbinger of Increased Prostate Cancer Risk. Atlas of Science

Since the introduction of prostate-specific antigen (PSA) as a blood test in 1992, the number of men diagnosed with prostate cancer increased dramatically. Because PSA detects men who are asymptomatic two things occurred. First, many of the

Discovery of new genes in schizophrenia: the importance of rare diseases in psychiatry

Discovery of new genes in schizophrenia. AoS

Schizophrenia is a major psychiatric illness affecting one percent of the population worldwide. Patients suffering from schizophrenia present delusions, hallucinations, abnormal behavior, impairment in daily life and cognitive deficits. Current treatments are insufficient in addressing all of

Is the color of museum mammal specimens an acceptable representation of the color of live animals?

he color of museum mammal specimens. AoS

Existing collections in Natural History Museums are often the basis of numerous studies in taxonomy, systematics, ecology, biogeography, management, conservation, etc., and studies based on biological museum specimens are to a large degree the basis of our

Stigma undermines prevention programs for the opioid crisis

Stigma Undermines Prevention Programs for the Opioid Crisis. AoS

The World Health Organization and the U.S. Commission on Combatting Drug Addiction and the Opioid Crisis, agree that opioid addiction is an epidemic. In the U.S., the Centers of Disease Control and Prevention framed three approaches to

The power of urine to understand genetic variants in the kidney

The power of urine to understand genetic variants in the kidney. AoS

Nephronophthisis is a rare genetic disorder of the kidney and the most common genetic cause of end stage kidney failure in children. It can be caused by mutations in more than 20 different genes. In the 50%

The ‘fundamental questions of obesity’: Asked and answered

Fundamental Questions of Obesity. AoS

Scientific progress requires the ability to discover which questions are essential and which are trivial. Yet until recently, there were three fundamental questions that were ignored in nutrition & obesity research: What is the defining characteristic of

On-demand, self-administered fast-dissolving insert for prevention of HIV, HSV, and HPV infections

Self-administered fast-dissolving insert for prevention of HIV. AoS

Microbicides are a potential discreet prevention method for empowering millions of women worldwide to protect themselves against incurable sexually transmitted infections (STIs) including HIV, herpes simplex virus (HSV), and human papillomavirus (HPV). For nearly three decades, much

Excessive postprandial VLDL remnants in plasma cause obesity and insulin resistance

Excessive postprandial VLDL remnants in plasma cause obesity and insulin resistance. AoS

Remnant lipoproteins (RLP) are the TG-rich lipoproteins metabolized by lipoprotein lipase (LPL) and increase in plasma after fat intake (Fig. 1), parallel with the increase of plasma triglycerides (TG). We have long thought that RLP in plasma

Are iron oxide nanoparticles neurotoxic?

Are iron oxide nanoparticles neurotoxic? AoS

Among the different types of nanomaterials, iron oxide nanoparticles (ION) awaken a particular interest due to their unique properties, including superparamagnetism and high biocompatibility. These features make them very suitable for a broad variety of uses, mostly

Stevensite: an efficient clay to retain tetracycline from wastewater

Stevensite: an efficient clay to retain tetracycline from wastewater. AoS

The tetracycline family of antibiotics are widely used for human therapy and animal feed. However, tetracycline (TC) is considered a contaminant of emerging concern in the environment due to its presence in wastewater effluents, surface waters and

Pain cognition in migraine

Pain cognition in migraine. AoS

The evolving concept of pain has led to the reformulation of its biological meaning by placing it in a much broader frame. Currently, we look at pain as a multidimensional sensation, aimed not only to the localization

Rigid calibrated tangled clots of laser light

Rigid calibrated tangled clots of laser light. AoS

Spreading of light structures during their propagation significantly limits the possible applications of lasers. This seemingly unavoidable property of waves can be “corrected” either in inhomogeneous media, such as optical fibers, or in nonlinear media in which

African sleeping sickness today

Tsetse fly. AoS

Human African trypanosomiasis (HAT), or African sleeping sickness, is one of 20 neglected tropical diseases listed by the World Health Organization (WHO). HAT can become a severe meningoencephilic disease developing after severe haemo-lymphatic infection. HAT takes two

New psychoactive substances: metabolites of synthetic cathinones induce cytotoxicity in human neuronal cells

New psychoactive substances. AoS

Recently, a large number of novel psychoactive substances (NPSs) have appeared on the European market. Their growing diffusion has become matter of worldwide concern and alarm for public health authorities, legislators, and clinical health specialists. They are

The RAS mRNA G-quadruplex: making undruggable cancer targets druggable

The RAS mRNA G-quadruplex. AoS

In many cancers, RAS proteins are constitutively activated by their oncogenic mutations or activation of their upstream molecules. RAS proteins play a central role in cancer cell malignancy, and drugs that target RAS are therefore believed to

Do people want to participate in decisions concerning their medicines?

Do people want to participate in decisions. AoS

Health and medication literacy are important factors linked to the outcomes of medical treatment (Table 1). Health literacy has been assessed in several countries all over the world and has been found to be limited. The level

Biomarkers for Alzheimer’s disease diagnosis: an eye on retinal inflammation

Biomarkers for Alzheimer’s disease diagnosis. AoS

Alzheimer’s disease is one of the most common neurodegenerative disorders. Alzheimer’s disease cases are constantly increasing worldwide due to population aging. Typical symptoms of the disease include memory loss, cognitive deficits, personality and behavior modifications. At the

Do metals in pregnant women have association to preterm births?

Metals are widely distributed in the environment. Recent reports have demonstrated the risk of preterm birth following heavy metal exposure. Preterm births include those occurring before 37 completed weeks of pregnancy, and the rate of preterm births

Modeling epidemics and analyzing Ebola incidence data using Numerus Model Builder

Epidemics are quintessentially dynamic with outbreak, peak-incidence, and fadeout phases. The timings of outbreaks are hard to predict, as happened with the 2014 outbreak of Ebola viral disease in West Africa. To evaluate the risks of outbreaks,

MicroRNAs control cellular transition of hepatocytes during liver regeneration

MicroRNAs control cellular transition of hepatocytes during liver regeneration. AoS

Among adult organs, the liver is unique in its intrinsic ability to regenerate after injury through the proliferation of fully differentiated cells. Hepatocytes, which are the most abundant type of cells in liver, are quiescent and rarely