What pH at the sites of calcification of an octocoral tells us

What pH at the sites of calcification of an octocoral tells us

Corals are marine organisms which elaborate calcium carbonate skeletons, a process known as biomineralization or calcification. More »

Zinc promotes myoblast differentiation activating Zip7 transporter and Akt signalling pathway

Zinc promotes myoblast differentiation activating Zip7 transporter and Akt signalling pathway

Skeletal muscle is a heterogeneous, dynamic and plastic tissue, which comprises 40% of adult human body mass. More »

Any cell organelle can be the starting point for toxicant and pathogen-induced cell death

Any cell organelle can be the starting point for toxicant and pathogen-induced cell death

Toxicants and pathogens often induce death of their target and host cells. In order to investigate the different ways they can achieve this More »

Metal-organic framework with dangling sulfonate groups for enhanced proton conductivity

Metal-organic framework with dangling sulfonate groups for enhanced proton conductivity

Metal-organic frameworks (MOFs) provide a versatile platform for tuning the chemical functionality of pore surfaces and thus have attracted an increasing amount of attention for applications in gas storage More »

 

Bayesian sparse neural networks for biomarker discovery with omics data

AoS. Bayesian Sparse Neural Networks for Biomarker Discovery with Omics Data

Recent advances in high-throughput biotechnologies, such as microarray and sequencing technologies, have provided an unprecedented opportunity for biomarker discovery, which potentially enhances the development of precision medicine. From a statistical point of view, the discovery of biomarkers

Preventing over-treatment in euthyroid patients with thyroid hormone abnormalities

AoS. Preventing over-treatment in euthyroid patients with thyroid hormone abnormalities.

Up to 12% of the U.S. population will be diagnosed with a thyroid condition. Because thyroid hormones affect every cell in the body, hypo- (low) and hyper-(high) thyroidism can be difficult to distinguish from other medical conditions.

Using AI to improve the quality and quantity of hand washing in hospitals

AoS. Using AI to improve the quality and quantity of hand washing in hospitals

Poor quality hand hygiene has been identified as the main contributor to the spread of hospital acquired infections. In the USA, they affect 2 million patients of which nearly 90,000 die. The cost of these infections is

The noxious effects of benthic diatoms on marine invertebrates

AoS. The noxious effects of benthic diatoms on marine invertebrates.

Diatoms dominate various marine and freshwater environments, at any latitude, and are responsible for up to 25% of primary production. They may be either free-living in the water column or produce benthic biofilms. Studies on the chemical

Carica papaya loaded PVA-Gelatin nanofibrous scaffold: a wound dressing material

AoS. Carica papaya loaded PVA-Gelatin nanofibrous scaffold

Every year millions of people worldwide encounter mishaps that may arise from burns, surgery, accidents, or chronic diseases compromising the skin’s integrity. These incidents can either result in lifelong functional impairment of the affected part of the

Aflatoxin exposure: pending regulation for vulnerable people

AoS. Aflatoxin exposure: pending regulation for vulnerable people.

Mycotoxins are toxins produced by filamentous fungi in food, especially because of water stress in the field or inadequate humidity and temperature in storage. Mycotoxins produce a toxic effect on animals and humans, from acute effects to

Mesalamine for the prevention of recurrent diverticulitis?

AoS.Mesalamine for the prevention of recurrent diverticulitis?

Recurrent diverticulitis represents a relevant clinical problem, involving up to a quarter of patients after the first episode of diverticulitis. Unfortunately, there are no evidence-based data that indicate a targeted therapeutic approach for the prevention of recurrent

Soft-particle gel electrophoresis

AoS. Soft-particle gel electrophoresis.

Particle electrophoresis in free solution or in gel media is a powerful technique for characterizing the surface properties of colloidal particles. Particle gel electrophoresis, that is, transport processes of colloidal particles in polymer gel media under an

Developing aptamers and 21st century skills through innovative course-based aptamer research

Among the growing list of aptamer applications, innovative aptamer Course-Based Undergraduate Research Experiences (CUREs) have merged the scientific demand of aptamers with the positive student outcomes realized through authentic research experiences. This demand for additional aptamers is

Sheath blight of rice: challenges and management

Rice (Oryza sativa L) is one of the most widely consumed cereal crops, grown in more than a hundred countries. Around 40,000 different varieties of rice exist in the world, with China producing the largest amount of

Cryo-electron microscopy in drug development

AoS. Cryo-electron microscopy in drug development

Cryo-electron microscopy (cryo-EM) is becoming the method of choice in structure determination of membrane proteins and has great potential for structure-based drug discovery (SBDD). Cryo-EM provides high-resolution structural information of a membrane protein without the need for

TMEM165; The Bermuda triangle of glycosylation and Golgi Mn homeostasis

During evolution, eukaryotic cells have acquired a complex network of endomembranes delimiting distinct organelles with specific cellular functions. In mammals, the rough endoplasmic reticulum (ER) and the Golgi apparatus are two key organelles of the secretory pathway

Strong primary healthcare may reduce mortality

AoS. Strong primary healthcare may reduce mortality.

Healthcare is variably organized across the world. In some places, people attend medical specialists such as cardiologists and urologists directly. In other places, people attend primary care physicians for most health problems and, if necessary, they refer

Global climate change and mental health

AoS. Global climate change and mental health

In the past decade, several empirical studies and systematic reviews of the literature have documented the mental health impacts of global climate change.  However, the range of impacts and their relationship to specific forms of climate change

Atmospheric and genetic parameters influence Rhinovirus transmission

Rhinoviruses are a diverse set of very small and common viruses, repeatedly infecting humans in the course of a single year. For most people, infection usually results in mild common cold symptoms, and spontaneously resolves without the

Botulinum toxin and occupational therapy for Writer’s Cramp

AoS. Botulinum toxin and occupational therapy for Writer’s Cramp

Dystonia is a neurological disorder characterized by abnormal postures that interfere with making movements. Writer’s cramp is the most common type of dystonia involving the upper extremity. Patients initially experience painless loss of control while writing, discomfort

Can SEM/EDX analysis be useful in prosecution of medical malpractice?

AoS. Can sem/edx analysis be useful in prosecution of medical malpractice.

Forgetting surgical gauzes within a patient’s body after surgery is a serious matter but also sadly known to the newspapers. The retained gauzes may cause severe inflammatory reactions and numerous complications up to death; exceptionally, they can

Targeted GRP78 pathway for improved vision in diabetic retinopathy

AoS. Targeted GRP78 pathway for improved vision in diabetic retinopathy.

Diabetic retinopathy, is a complication of diabetes which causes vision loss and eventual blindness in adults. People with diabetes have more sugar in their blood than normal, which causes their bodies not to function correctly. Often proteins

A method for highly sensitive detection of D-amino acids

AoS. A method for highly sensitive detection of D-amino acids.

D-amino acids have recently attracted much attention in various research fields including medical, cliDical and food industry due to their important biological functions that differ from l-amino acid; thus, there has been an increasing need to develop

Nickel free, built-in nanotubular drug eluting stents

AoS. Ni-free, built-in nanotubular drug eluting stents

Coronary Artery Disease is a common cause of heart failure. Coronary Artery Disease (CAD) is caused by the accumulation of lipids and fats within an injured arteries’ walls and restricts the blood flow to the heart muscle