Macrophage-myofibroblast transition: a novel target for stopping kidney disease
Kidney is one of the major organs in our body for detoxification. Its failure is an important cause of patient mortality that serves as a primary disease and a lethal complication in a range of diseases such
Perspectives for anti-tuberculosis therapy with additional drug activities to counteract drug resistance
Generally, antibiotic therapies use single antibiotics to combat sensitive bacteria. The standard of antituberculosis therapy includes four antibacterial agents that all have different modes of activities in the initial phase of a tuberculosis infection with mycobacterium tuberculosis.
Monitoring of the consumption of new psychoactive substances in wastewater from Athens
Licit and illicit drug use monitoring is an important subject for public health. Almost every substance that people consume is excreted as parent compound and as metabolites via urine and faeces and ends up in the sewage
Is Lebanese oregano safe to consume?
Oregano, Origanum syriacum, is an aromatic perennial herb that is widely used in the Middle East. It is a delicious, cheap staple food that is consumed by all classes. Oregano is not only used for consumption purposes but is
Interactive/combined effects of climate change and pollutants is a major threat to marine biota and seafood worldwide
Both climate change and pollutants are a global problem and a major threat to social, economic, and environmental sectors. Climate change stressors are rise in temperatures, ocean acidification (decrease in pH), sea-level and hypoxia (dissolved oxygen <
Method to measure calcium signaling in nanometer-sized primary cilia
Cilia are slender microtubule-based organelles that protrude from the apical membrane in most adherent cells. Studies looking into the mechanosensory function of the primary cilium have proved it to be an essential cellular organelle. When exposed to
Does tangential radiation for breast cancer cover internal mammary nodes?
Breast cancer is one of the most common cancers in women in the United States. Radiation is a very commonly used treatment modality for breast cancer: it is offered to nearly all patients after lumpectomy (removal of
The year of the honey bee with respect to its physiology and immunity
It has been known for many years that in temperate climates, the European honey bee, Apis mellifera, exists in the form of two distinct populations within the year, short-living summer bees and long-living winter bees. Summer populations’
Is the ACTN3 gene a real “speed gene” in horses?
The ACTN3 gene encoding α-actinin-3 in humans is considered to be a key factor in determining the predisposition to short- or long-term exercise (sprint or endurance). In addition, mutations within it are used for commercial genetic tests
Antifouling photo-bactericidal combined effect of a Ag@nanoMOF
The formation of bacterial biofilm on surfaces occurs naturally and its inhibition and treatment to limit the propagation of infectious diseases is still an unsolved challenge. Traditionally, several antibiotics have been used to mitigate the formation of
Left-handers are not at risk for mathematical learning difficulties
Nearly one in every ten people is left-handed, a number that seems to have remained the same through time and place. Interestingly, individuals with neurodevelopmental disorders, such as low functioning autism or intellectual disability, are more likely
Adverse food reactions in cats: 1000 cases
Wholesome nutrition is the key to maintaining a healthy immune system and resistance to disease. Commercial foods given to animals may not be truly balanced in major nutrients, minerals and vitamins, and some have chemicals added to
Historical stability of the human aging rate and its decline in our time
Using age-related mortality data for 40 countries, it is shown that the rate of aging does not change significantly over history and is almost the same for different countries from the mid-18th to the mid-20th century. However,
Microalgae-based wastewater treatment for nutrients recovery
The world may face deficits of water supplies in the decades ahead, for both potable water and water for irrigation, due to human population growth, droughts and floods due to climate change, contamination of water resources, and
EML1: an entry point to study cellular mechanisms at the origin of brain malformations
Cerebral cortical development is a tightly regulated process, depending on dividing progenitor cells that ultimately produce neurons that then migrate to find their appropriate positions in the developing cortex. Certain genetic conditions as well as environmental factors
A novel measure for predicting OSA whilst awake
Obstructive sleep apnea (OSA) is a common sleep disorder, and its prevalence increases significantly with age. Despite being massively under-diagnosed, the latest estimation of OSA prevalence is >1 billion globally. OSA diagnosis is based on an overnight
Experiences of other identities and Dissociative Identity Disorders in the continuum of Non-Ordinary Mental Expressions
Dissociative Identity Disorders (DIDs) – including experiences of other identities, multiple personality and possession – are an intriguing topic entailing deep historical, cultural and epistemological implications that run through the entire history of the human kind. Indeed,
Nanomaterials as promising alternative in the infection treatment
Nanotechnology offers groundbreaking solutions for the management of infections in the current era when the vast majority of antibiotics has become inefficient. Overcoming antimicrobial resistance and biofilm formation constitute a major challenge. In this review, we focus
Short sleep duration is associated with symptoms of depression
The average person spends about a third of his life sleeping, but for the busy and the ambitious that is a lot of time. Many of us would rather spend that time working on important projects or
Specific and non-specific biomarkers in neuroendocrine gastroenteropancreatic tumors
Neuroendocrine tumors (NETs) are a heterogeneous group of rare malignancies that can arise in almost all organs, although gastroenteropancreatic site (GEP) is the most common. Symptoms are rarely specific, and clinical manifestations may be evident only in
