Deep Molecular Profiling to understand the biology of Alzheimer disease
Alzheimer disease (AD) is a complex, polygenic disease with genetic, cellular, pathologic, and clinical heterogeneity. Advances in high-throughput sequencing and omics technologies have accelerated the drive toward personalized medicine. Human bio-specimens using these high-throughput platforms have emerged
Cosmology in a cell: Defect annihilation in liquid crystals
Topological defects are configurations of the order parameter which cannot be transformed continuously into a uniform state. They have been observed in various areas of physics, such as alloys, semiconductors, particle physics and cosmology. Due to the
Ultralong room-temperature phosphorescence of a solid-state supramolecule
Glows in the dark after removing energy input, named room-temperature phosphorescence (RTP), has got enormous attention because of its various application in biological imaging, light-emitting devices, information storage and encryption, and so on. However, achieving ultralong RTP
Essential fatty acids in the vegan/total vegetarian diet
People choose vegetarian/vegan diets and for many reasons, however, these diets require careful dietary planning. The essential polyunsaturated n-6 (omega-6) and n-3 (omega-3) fatty acids are required for synthesis of inflammatory compounds, cell membranes, skin, brain and
WRGSD: improving reliability and efficiency for coastal monitoring network
Water-quality response grid-based sampling design (WRGSD) using optimization and multi-factors assessment can reliably detect a variety of the impact of human activities. The sampling design are optimized by clustering and dividing the water quality response grid to
Cs adsorption by Mn‒Fe-based Prussian blue analogs formed in agarose gel
The Fukushima nuclear accident triggered a massive release of radioactive cesium (Cs) isotopes into the environment and generated a large amount of contaminated water. Because Cs isotopes pose serious threats to the environment (particularly the aquatic environment),
Inner peace and faith: the impact of spiritual well-being on anxiety protection in healthcare workers
Anxiety is considered the most common mental disorder. The anxiety symptoms (AS) are usually associated with several physical and mental illnesses. Previous investigations have shown that AS are exceptionally high in healthcare workers (HCWs). Furthermore, some studies
Silkworms turning your shirt into a cell phone battery
Feeding Bombyx mori larvae with nanostructured materials such as CNTs, graphene, TiO2 and other metal oxides have been investigated in recent reports. The feeding process proved that Bombyx mori larvae can intake nanostructured materials, which affect the
Actinobacteria from Algerian ecosystems as a rich source of bioactive molecules promising for new potential drugs
Secondary metabolites are molecules not essential for the growth and development of microorganism, mainly having a defence role. They have shown a great potential for the discovery of drugs and their study still draws attention to the
Low phosphate after modern intravenous iron? Fibroblast growth factor 23 may be the key!
Iron is an essential substance with a number of roles in the body. Anaemia caused by low iron (iron deficiency anaemia) can worsen disease outcomes and reduce the quality of people’s lives. Iron deficiency anaemia can be
The SETOC: Visualizing carcinogenesis through a different lens
The Systemic-Evolutionary Theory of the Origin of Cancer (SETOC) is a recently proposed theory based on two fundamental principles: (i) Margulian evolution as a process of cooperation and endosymbiosis and (ii) Systemic cell biology understood as the
Cerebral venous hemodynamic in a rat model of acute epidural hematoma
Traumatic brain injury (TBI) is currently one of the most serious public-health problems, with an annual global incidence rate of 319/100,000. TBI includes primary injuries directly caused by mechanical stress and shear forces, as well as secondary
Muscle pain treated with injected normal saline solution
Pain comes in all shapes and sizes. Ranging from acute to chronic, from nociceptive and myofascial to neuropathic, pain is a part of life. Myofascial or muscle pain, is among the most common. With a lifetime prevalence
A new procedure to accurately define Nitrate Vulnerable Zones
The Nitrates Directive of the European Union (91/676/EEC) aims to reduce and prevent water pollution caused by nitrates from agricultural sources. It establishes that water resources should be considered polluted when nitrate concentration exceeds 50 mg L-1.
Recording in the emergency department: illegal or immoral?
Patients and staff should expect privacy in emergency departments and should not be recorded without giving their consent in advance. Emergency departments (ED) use audiovisual recordings to document clinical information and to assist with diagnosis and treatment.
How PET ameliorates 90-Yttrium therapy in inoperable liver cancer patients?
Increased synthesis of blood vessels and blood supply are essential characteristics of a tumor to secure nutrient delivery and growth. One of the treatment options for inoperable liver cancer (hepatocellular carcinoma, HCC) is to apply a form of
A novel digital nasoalveolar molding approach for cleft lip and palate
Presurgical nasoalveolar molding (PNAM) is a widely accepted approach applied before cheiloplasty for infants with unilateral cleft lip and palate (UCLP), which can effectively reduce the width of the cleft gap, to align and approximate the intraoral
Effectiveness of infrared tympanic thermometry during physical activity in the heat at a solar radiation of 500 W/m2 or less
Exposure to high solar radiation in the heat poses a thermoregulatory challenge and increased risks of exertional heat-related illness in workers and exercising individuals. Core temperature monitoring is important during physical activity in the heat to prevent
Arthroereisis for symptomatic flexible flatfoot deformity in young children
Flexible flatfoot is a common deformity in the pediatric population. The foot due to ligamentous laxity is unable to support the body weight at its three contact areas to the ground (The plantar aspect of the calcaneus,
Synergies between ultrasound and aminated nanoparticles in the synthesis of DHP pharmaceuticals
Today, attentions to the synergistic effects have raised due to bringing convenience and expedition into the complex processes. In the field of catalysis, synergistic effects between the ultrasound waves (USWs) and the nanosized heterogeneous species is one
