More Paleolithic-like lifestyles and diets associated with lower colorectal cancer risk
Colorectal cancer (CRC) is the second leading cause of cancer deaths among women and men combined in the United States. CRC incidence (i.e., the rate of new diagnoses) varies about 20-fold across countries. The incidence among immigrants
What happens inside the eye: fluid forces under physiologic movements
The vitreous is a gel-like structure that completely fills the posterior part of the eye. Doctors inject drugs directly inside the vitreous to cure sight-threatening diseases like age-related macular degeneration. These are relatively new therapies; few is
High potential polymer carriers to enhance antibiotic efficiency in bacterial biofilms
Cystic fibrosis (CF) is a frequent genetic disease resulting in chronic and difficult-to-treat pulmonary infections and inflammation that needs a lifelong treatment with aggressive antibiotic therapy by oral, intravenous or inhaled routes. The most abundant bacterial species
Associations between mathematics development and visuo-spatial perception in children with cerebral palsy
Previous research has suggested that children with cerebral palsy (CP) have difficulties with visuo-spatial perception. We wanted to find out if there was an association or relationship between the children’s visuo-spatial abilities and the development of their
Complexity and behavioral diversity in evolving populations under uncertainty
Evolutionary Game Theory – an application of game theory to evolving populations in biology, introduced by Maynard Smith and Price in 1973 – provides a mathematical framework describing dynamics of competition and strategic behavior according to Darwinian
3D-printed chitosan scaffolds for the improved in-vivo wound healing in diabetic rats
In the tissue engineering context, fabrication of porous three dimensional (3D) printed chitosan (CH) scaffolds for skin tissue regeneration and their behavior in terms of biocompatibility, cytocompatibility and toxicity toward human fibroblast (Nhdf) and keratinocyte (HaCaT), was
Stable housing can significantly improve health outcomes in women living with HIV
Unstable housing, including homelessness, is a key socioeconomic determinant of poor health outcomes and premature death in the United States. Housing-insecure individuals are more likely to delay seeking medical care due to costs, lack of health insurance,
Circulating fibrocytes as possible new target of abatacept effect in systemic sclerosis patients
Systemic sclerosis (SSc) is an autoimmune connective tissue disease characterized by microvascular and immune response alterations followed by a progressive fibrosis, which is the consequence of an excessive production and deposition of extracellular matrix molecules, primarily fibronectin
Prefrontal-auditory communication in fear discrimination
Identifying neural networks that infer safety versus danger is of great interest in the scientific field. Fear generalization reduces the chances of an animal’s survival and leads to psychiatric diseases, such as post-traumatic stress disorders and phobias
Parasite control – breaking the worm cycle
Gastrointestinal parasites are a major health challenge for all grazing animals, whether they are located on paddocks and rangelands (such as horses, sheep cattle or goats) or in zoos (such as giraffe and zebra). In a previous
kINPen09 plasma treatment leads to antimicrobial effects against Candida albicans biofilms
Microbial communities are an increasing problem in medicine but also in industry. Thus, an efficient and rapid removal of biofilms from surfaces is becoming increasingly important. With the aid of the kINPen09, a radiofrequency plasma jet (RFPJ)
Ketamine, not TPS potentiates glutamate-induced Ca neurotoxicity
There is growing concern about anaesthesia effects on the developing brain because commonly used anaesthetics can cause neurodegeneration and long-term neurocognitive deficits. In the developing brain, GABA-R agonists and NMDA-R antagonists cause neurotoxicity and apoptosis. Comparing their
Iron: it is all in the core
Iron, the most abundant element on the Earth’s core, is an essential substance necessary for a number of reactions in the body which lead to the production of necessary energy allowing optimal function. Iron deficiency (ID) and
Pulmonary arteriovenous malformations (PAVM) should be treated by embolization
Pulmonary arteriovenous malformations (PAVM) are congenital vascular communications in the lungs. They act as shunts so that the blood running through these malformations is not oxygenated or filtered (Fig. 1). These patients will typically have dyspnea on
Nanocrystalline 3D homojunctions for next generation opto-electronics
Planar pn junctions constitute an integral part of optoelectronic devices. Inorganic semiconductor crystals offer superior properties compared to organics but high-grade crystals are expensive and difficult to produce in large volume. Bulk heterojunction (BHJ) and ordered heterojunctions
Are Baltic grey seals (Halichoerus grypus grypus) exposed to phenol derivatives?
Plastics and endocrine active compounds (EDCs) reaching the sea is a very current topic. Global society is beginning to notice plastics accumulating on beaches, in coastal waters and in so-called “Great Garbage Patches” in the oceans. The
Duodenal neuroendocrine tumors: what we really know about them? An Italian multicentre experience
Duodenal neuroendocrine neoplasms (dNENs) are heterogeneous tumors and represent up to 3% of all duodenal tumors and 2–3% of all gastrointestinal tumors. Despite clear differences, dNENs have been always treated together with either gastric neuroendocrine tumors or,
Dynamic electron microscopy: recording of ATP-induced myosin head movement in living muscle myosin filament
Muscle contraction results from relative sliding between actin and myosin filaments, caused by cyclic movement of myosin heads coupled with ATP hydrolysis. It is generally believed that individual myosin heads M), extending from myosin filaments, first bind
Skewed signaling through RAGE strength the tumor growth-promoting activities of M2 macrophages
Tumors are complex tissues composed by both non-cellular components, mainly matrix proteins, and different stromal cell types, which are under an active cross talk with tumor cells. Tumor-associated macrophages (TAMs) are the major leukocyte population among the
Urbanization facilitates migration of the human health pest, Western black widow spider
By 2050, more than half of the global human population is expected to live in urban areas. As these urban areas rapidly grow, they replace some of our most pristine habitats. One effect that urbanization has is
