What pH at the sites of calcification of an octocoral tells us

What pH at the sites of calcification of an octocoral tells us

Corals are marine organisms which elaborate calcium carbonate skeletons, a process known as biomineralization or calcification. More »

Zinc promotes myoblast differentiation activating Zip7 transporter and Akt signalling pathway

Zinc promotes myoblast differentiation activating Zip7 transporter and Akt signalling pathway

Skeletal muscle is a heterogeneous, dynamic and plastic tissue, which comprises 40% of adult human body mass. More »

Any cell organelle can be the starting point for toxicant and pathogen-induced cell death

Any cell organelle can be the starting point for toxicant and pathogen-induced cell death

Toxicants and pathogens often induce death of their target and host cells. In order to investigate the different ways they can achieve this More »

Metal-organic framework with dangling sulfonate groups for enhanced proton conductivity

Metal-organic framework with dangling sulfonate groups for enhanced proton conductivity

Metal-organic frameworks (MOFs) provide a versatile platform for tuning the chemical functionality of pore surfaces and thus have attracted an increasing amount of attention for applications in gas storage More »

 

Ferrate technology: an innovative solution for sustainable sewer and wastewater management

AoS. Ferrate Technology: Revolutionizing Sustainable Sewer and Wastewater Management

Sewers might be out of sight, but they play a huge role in shaping the well-being of a society. They quietly carry away all the wastewater from our homes, businesses, and factories, preventing harmful viruses, bacteria, and

Sleep abnormalities in different clinical stages of psychosis

Sleep abnormalities are commonly observed in individuals with schizophrenia and related psychotic disorders. Research shows that over half of people with these conditions have trouble sleeping. Poor sleep also often contributes to the development and worsening of

A compact high yield isotope enrichment system

Highly enriched isotopes such as 10B, 98Mo, and 100Mo are in great demand for the manufacturing of radioactive isotopes for medical diagnostic imaging studies and therapeutic applications. In order to produce useful quantities of the medical radioisotopes,

Late second trimester miscarriages

AoS. Late second trimester miscarriages

A second trimester miscarriage is the spontaneous loss of a pregnancy between 12 and 22 weeks of pregnancy. This is indeed a very sad experience to the parents. It has been said that a miscarriage may cause

Making Christmas trees under duress, or how cells regulate the production of ribosomal RNA

AoS. Making Christmas trees under duress

Some of the most enduring images for a molecular biologist are electron microscopy micrographs of the so-called “Christmas trees”, famously first observed by Oscar Miller from newt oocytes in 1969. These intriguing structures (Fig. 1A) capture the

Rabbits with mammary carcinomas as a model for comparative pathology and translational science in breast cancer research

AoS. Rabbits with mammary carcinomas as a model for comparative pathology and translational science in breast cancer research

Within a breeding colony of rabbits, the American pathologist Harry Greene (1904-1969) observed that mammary carcinomas were restricted to certain families. This is suggestive of a familiar predisposition as it occurs in human breast cancer. In rabbits,

Could mometasone furoate be a viable glucocorticoid with fewer metabolic adverse effects?

AoS. Could mometasone furoate be a viable glucocorticoid with fewer metabolic adverse effects?

Glucocorticoids are medications widely used to treat inflammation and allergies, and in contexts of immunosuppression such as after transplants. They are well-established and safe. The problem is that, when used for a long time, or in high

Galectin-9: A new target for beating atherosclerosis?

AoS. Galectin-9: A new target for beating atherosclerosis

Atherosclerosis is a chronic medical condition characterised by the accumulation of fat in the walls of blood vessels, which obstruct the normal flow of oxygen-rich blood and can have severe health consequences. Peripheral arterial disease (PAD) is

Naturally occurring peptide may tackle the “root cause” of obesity-related diseases

Obesity typically occurs when a person eats more calories than they need for their daily activity. It results in a build-up of fatty tissue around all organs. In lean people, fat tissues work closely with hormones to

Linking copper, tyrosines and protein aggregation in Alzheimer’s disease

The prevalence of Alzheimer’s disease (AD), the most common cause of dementia nowadays, is expected to increase within the coming years, representing a serious threat for society and the healthcare system. For this reason, a lot of

Improving assessment of arthritis models to better reflect human symptoms of disease

AoS. Improving assessment of arthritis models to better reflect human symptoms of disease

Rheumatoid Arthritis (RA) is a common inflammatory disease that is characterized by swelling and tenderness of multiple joints. The resulting pain and joint stiffness cause disability for patients and treatment to control the inflammation is required to

Systemic therapy in juvenile localized scleroderma

AoS. Systemic therapy in juvenile localized scleroderma

Juvenile localized scleroderma, also known as morphea, is an rare condition, it occurs around 1 in 5000 children, where the skin and the tissues underneath the skin like fat tissue, muscle, tendons, and bone, get inflamed and

Can we accurately diagnose different clinical variants of Progressive Supranuclear Palsy using IPMDS-PSP criteria?

AoS. Can we accurately diagnose different clinical variants of Progressive Supranuclear Palsy using IPMDS-PSP criteria

Progressive Supranuclear Palsy (PSP) is the second most common degenerative parkinsonian syndrome after idiopathic Parkinson’s disease. PSP is a clinically heterogeneous disorder with several clinical variants. The two most common clinical variants are the Richardson (PSP-RS) and

Microbial community assembly and the microbiome revolution

AoS. Microbial community assembly and the microbiome revolution

Microbial communities (i.e. groups of potentially interacting microbial populations that co-exist in space and time) most commonly represent complex and highly diverse assortments of microbial populations, each possessing different genomic features that reflect on their specific life

Exploring gap junction networks required for zebrafish skin pattern formation

The study of pattern formation has advanced to a new phase involving channel molecules acting on bioelectric signals, with gap junctions being major relevant factors. Gap junctions are composed of connexin proteins: six connexins form hemichannels/connexons on

Social rank recognition is altered in autism spectrum disorder

AoS. Social rank recognition is altered in autism spectrum disorder

Humans and many other animals spend their lives in social groups, along with constructing social hierarchy within the groups. Since social hierarchy is a principal determinant for allocation of limited resources for individuals in a group, assessments

Is that possible to prevent parasitic iatrogenic blood bank transmission?

AoS. Is that possible to prevent parasitic iatrogenic blood bank transmission?

Chagas disease (CD) is neglected tropical disease (NTD) that affects over 6 million people mainly in the poorest areas of Latin America. CD also represents a public health concern in non-endemic areas such as North America, Asia,

Waking a sleeping giant: How increasing Africa’s research output can benefit global cardiovascular health?

AoS. Waking a sleeping giant: How increasing Africa's research output can benefit global cardiovascular health?

Africa is home to 1.4 billion people, of whom 55 million suffer from cardiovascular disease (CVD). Despite this, Africa contributes to only 1.7% of the world’s cardiovascular science. We studied 179 clinical trials led by African researchers

Lipid nanoparticles loaded with CpG oligonucleotides exert an antitumor effect via immunomodulation

AoS. Lipid nanoparticles loaded with CpG oligonucleotides exert an antitumor effect via immunomodulation

Since the emergence of immune checkpoint inhibitors (ICIs), cancer immunotherapy has dramatically developed. However, its drawback is the low overall response rate to its therapeutic effect. The efficacy of immunotherapy is suggested to depend on the immune

Sustainable solutions: Tamarind Seed Kernel powder (TKP) adhesive as a green alternative for lignocellulosic composites

The majority of petroleum-based adhesives applied in the wood industry today, particularly formaldehyde-based adhesives. Their application trend is increasing due to their wide availability, superior bonding, durability, and resistance to heat and moisture. However, formaldehyde-based adhesives continuously