Monthly Archives: September 2017
Erufosine increases RhoB expression in oral squamous carcinoma cells independent of its anticancer mechanism of action
Erufosine is an ether–lipid-derived synthetic compound belonging to the group of alkylphosphocholines (APCs). This chemotherapeutic agent exhibits pronounced anti-leukemic activity without affecting the normal hematopoiesis and exerts its influence by modulating signal transduction pathways in malignant tumor
14th International Conference and Exhibition on Nanomedicine and Pharmaceutical Nanotechnology. Amsterdam, Netherlands. April 09-11, 2018
Conference Series Ltd organizes highly notable pharmaceutical conferences throughout the world. Currently we are bringing forth “14th International Conference and Exhibition on Nanomedicine and Pharmaceutical Nanotechnology” (NanoMed 2018) scheduled to be held during April 09-11, 2018 at
A network of stuttering
Network science uses techniques from mathematics, computer science, and several other fields to study complex systems. Nodes are used to represent an individual in the system, and connections are placed between nodes that are related in some
Factors increasing mortality of the elderly following hip fracture surgery
Hip fracture is one of most common public health problems with significant financial burden on the patient and health care systems. Risk of mortality in elderly patients with several comorbidity is high especially during first year following
Neonatal programming of pesticide-induced neurodegeneration
Permethrin (PERM) is a pesticide of the pyrethroid class widely used in agriculture to protect crops and in general its main application is as insect repellent. It is also a component of many creams against skin diseases
Chemical synthesis of 12-HHT and related metabolites derived from polyunsaturated fatty acids
Collaboration of organic chemistry and biology has successfully developed a new area of research. Science of metabolites derived from polyunsaturated fatty acids by COX or LOX is one of successful examples. These metabolites are chemical mediators that
The aged immune system in multiple sclerosis: focus on B cells
Multiple sclerosis (MS) is an autoimmune disorder that affects the brain and spinal cord. A chronic inflammatory reaction causes breakdown of myelin surrounding the axons, leading to a disturbed transmission of nerve impulses. Symptoms of MS include
Are school-based interventions effective in preventing traffic accidents?
According to the World Health Organization, more than one million people die every year on the world’s roads, and another 20 to 50 million get injured because of traffic accidents. Sadly, traffic accidents are the first cause
The smart light modulators of the scarab beetle Chrysina gloriosa
Many insects own a tessellated carapace with bumps, pits or indentations. Little is known on the physical properties of these geometric variations, and biological functions are unknown or still debated. Beetles from the genus Chrysina show vivid
Scientists don’t have to travel alone; solutions can come from the crowd
Science is sometimes perceived as a lonely affair where a lone genius strives to break the code that will unlock hidden knowledge deep inside the data. Without question the contributions of great scientists are of value, but
Cuba responds to Ebola
The first known case of Ebola virus disease appeared in the West African country of Guinea In December 2013. By September of 2014, over 1900 deaths from Ebola had been reported in the region. The United Nations
Arabinoxylan rice bran (Biobran) for the treatment of Hepatitis C
Hepatitis C virus (HCV) has infected approximately 150 million people world-wide (about 3% of the world population) and causes approximately 700,000 deaths each year. It has been shown to be a causal factor of liver cirrhosis, scarring
Cases of trephination in ancient Armenia skulls
Trepanation of the cranial vault, one of the most intriguing paleoneurosurgical techniques. Trepanation has garnered intense interest, because it represents an early form of cranial surgery practiced well before the advent of modern medicine. Trepanning seems to
Are there genetically modified animals in the supermarket?
Animal breeders have used selective breeding, a form of directed evolution, since animals were first domesticated. Using this approach, individual animals are chosen to be parents of the next generation because they exhibit a desirable trait or
Fabrication of magnetic activated carbon as a new adsorbent for ultrasonic assisted magnetic solid phase dispersive extraction of bisphenol A from milk
Bisphenol A (BPA), is an organic chemical compound that has been widely used as a monomer in the manufacturing of polycarbonate plastics and epoxy resins, in thermal paper production and as an additive in the formation of
Can vitamin E protect cells from persistent organochlorine contaminants such as polychlorinated biphenyls?
Many toxic substances, mostly man-made, are present and widespread in our environment. Eventually they become a part of the food chain — e.g. pesticide residues, veterinary drugs and pharmaceuticals, contaminating substances originating from industrial processes – heavy
How its great therapeutic potential can finally be realized
Fibrinolysis refers to the body’s natural defense system against blood clots, which are made principally of a protein called fibrin. “Lysis” is the Greek word for dissolving, therefore, dissolving fibrin clots. Fibrinolysis is needed because clots are
A stone during pregnancy – more painful than childbirth
Kidney or ureter stones in pregnancy are a major health concern and are one of the most common causes for abdominal pain in pregnant women. Stones may lead to a blocked kidney, kidney infection which may spread
Could accelerated physical therapy after hip and knee replacement get patients home sooner?
The joint replacement procedures total hip arthroplasty (THA) and total knee arthroplasty (TKA) are among the most effective surgical procedures in modern medicine. In the United States the number of THA procedures is projected to increase 174%
Occupational causation of sarcoidosis
Sarcoidosis is an uncommon disorder of unknown cause characterized by widespread granulomas, a distinctive tissue response resembling that caused by tuberculosis. A number of articles have appeared within the past few years inferring occupational causation based on
