Monthly Archives: March 2018

Micro-Flow Imaging: spotlight on PLGA microparticle agglomeration

Since the 1980s, engineers are capable of precisely controlling fluids inside channels of a few microliter or less. Recent advances in microfluidics have led to the development of powerful analytical techniques. One of those techniques is Micro-Flow

Internal structure of scaly armor enables bite resistance in the African Pangolin

Natural materials often exhibit excellent mechanical properties that are packaged within lightweight structures. This exceptional performance of natural materials is achieved through efficient use of architectural design, which is difficult to replicate synthetically. Recent efforts in solid

Unlocking the anticoagulant potential of Barrel Jellyfish tentacle extract

Cnidarians in spite of their toxicity have long been indicated as a potential source of natural bioactive compounds of pharmacological concern useful to develop new drugs or biomedical materials. A number of metabolites, anti-cancer, anti-microbial and anti-oxidant

Obesity fuels breast carcinogenesis: What is the molecular basis?

Excess body weight is associated with the primary risk of 13 distinct cancers and is generally considered a poor prognostic indicator for patients diagnosed with a variety of malignancies. Obesity is increasingly recognized as a risk factor

The longest single crystal structure confirmed azaacene derivative: one step forward large conjugation molecules

Organic semiconductors are supposed to be the next generation semiconductors, which shows many great advantages over silicon. For example, their devices are easier and cheaper for fabricating and can be flexible. Their variable molecular structures can be

Linear-shaped and ring-shaped Re(I) multinuclear complexes work as highly photofunctional molecule

Octahedral six coordinated rhenium(I) (Re) diimine complexes with three carbonyl ligands show long-lived and strong room-temperature luminescence, attributed to a low-lying triplet metal-to-ligand charge-transfer (3MLCT) excited state. Tunability of their properties emerges from synthetic versatility and therefore

World Congress on Advanced Pharmacy and Clinical Research. Sydney, Australia. July 16-17, 2018

Conference Series LLC Ltd invites all the participants from all over the world to attend the “World Congress on Advanced Pharmacy and Clinical Research” during July 16-17, 2018 at Sydney, Australia which includes prompt keynote presentations, Oral talks, Poster presentations and Exhibitions.

More intensive anticoagulation is associated with a lower stroke risk after elective cardioversion in atrial fibrillation

Atrial fibrillation (AF) is the most common arrhythmia of the heart and elective cardioversion (ECV) is a common procedure in converting AF to normal sinus rhythm. AF carries an increased risk for stroke and a substantial portion

What response of skin blood flow in hindlimb does electrical stimulation of forelimb induce?

The nervous system includes the central nervous system (CNS) and autonomic nervous system (ANS). Abundant evidence exists to show that structures and functions of the CNS in humans are bilaterally asymmetrical. The best known example of brain

Molecular transformation from monocyclic to chiral tricyclic scaffold by using organonickel catalyst

Waste-free (or -minimized) molecular transformations from chemical feedstocks to complex structures is a state of the art, as it provides a cost-effective, environmentally benign and practical route to natural products as well as active pharmaceutical candidates (API).

Modern medicine is poisoned by professional arrogance

Modern medicine is poisoned by professional arrogance. The antidote is professional humility. The arrogance is exacting a high price. Several examples prove the point. For forty years physicians regularly irradiated the thymus glands of children because of

Which is the best way to intraoperatively detect an electrode array misplacement in cochlear implantation surgery?

Cochlear implantation (CI) is a worldwide well-known procedure for the treatment of severe to profound hearing loss. New surgical techniques and technological upgrades in the past years have helped to decrease complications of this procedure, but they

A combination of medical therapy and liver transplantation save children with acute liver failure

Acute liver failure (ALF) in children is defined as a severe impairment of liver function characterized by biochemical evidence of acute liver injury, coagulopathy (INR ≥2.0) regardless of the presence of hepatic encephalopathy (HE) and no history

Effect of the new hybrid 3,5-dipalmitoyl-nifedipine on the ischemia / reperfusion simulation

The myocardial ischemia process is a global health problem. Damage after myocardial ischemia and reperfusion (I/R) is the leading cause of morbidity and mortality globally. Hypertensive patients are most affected by I/R. This work investigated the acute

Cyclists burn more fat with New Zealand blackcurrant – dose responses

Fruit and vegetables are made from multiple constituents and appropriate daily consumption provides positive health benefits. The bright colouration of fruits and vegetables comes from the polyphenol content and these in part are attributable to the health

Bandaid immunization to prevent ear infections

Almost every child will develop an ear infection and unfortunately, some children will have seven or eight before their first birthday. These chronic infections can result in language, developmental and educational delays, all factors with long-term consequences.

Three-dimensional computed tomographic volumetry precisely predicts the postoperative pulmonary function

Surgical resection remains the principal treatment for early stage lung cancer, although new chemotherapeutic agents and molecular-targeted drugs have been developed. In order to conduct pulmonary resection safely, it is necessary to ensure that the patient’s postoperative

The lysosomal enzyme cathepsin D as novel therapeutic target for non-alcoholic steatohepatitis

The decrease in physical activity combined with increased caloric intake has led us to a global obesity epidemic. Obese patients can develop metabolic syndrome (MetS), which is a term used to assess the risk of a patient

Cyanobacteria: microbial factories for drug discovery

Cyanobacteria, the only prokaryotes that perform the oxygen-producing photosynthesis, are ancient organisms that shaped the atmosphere of our planet. In colonizing most waters and soils, where they face various environmental challenges and competition with many biological organisms,

Oxidative stress sensitivity of cancer cells could be altered by plasma membrane status

Oxidative stress is defined as “A status that the balance between the oxidation reaction and the antioxidant reaction is lost in our body, and that the oxidation state is dominant.” Oxidative stress is generally adverse for our