Category Archives: Research
Analysis of serum biomarkers and their correlation with pain and quality of life in the rare disease alkaptonuria
Alkaptonuria (AKU) is an ultra-rare disease causing an early onset, chronically debilitating spondylo-arthropathy due to deposition of an ochronotic pigment in joints and spine, which causes severe pain and greatly reduces patients’ quality of life. Despite an
Impact of decontaminant and microbiological media on Mycobacterium avium subspecies paratuberculosis
Mycobacterium avium subspecies paratuberculosis (Map) has aetiological significance in Crohn’s disease of humans, and chronic intestinal disease in domestic and wild ruminants. This opportunistic pathogen can proliferate inside its host, whilst restricted to grow in the environment.
For twins, the identity is a “yes” or “not” intrinsic property: they can be identical (monozygous) or non-identical (heterozygous). Classical identical twins can always be distinguished (at least by their mother!). In fact, it is always possible
How do people’s expectations compare to the reality of their recovery after a knee replacement surgery?
The decision to undergo a knee replacement is not one taken lightly by the patient or medical team. For many people with arthritis, medication and exercise therapies can help their symptoms, but when problems persist, a knee
Professional and pre-professional dancers spend years training in order to express the deepest experiences of the human condition. They acquire physical skills that translate into aesthetic works of art. Regardless of the dance form, whether classical ballet,
The need to convert and store energy in an efficient and sustainable way has already become one of the highest priorities of the new millennium. One possible solution to this challenge is the thermoelectric, which can be
The frozen elephant trunk (FET) procedure has prevailed because it has simplified the treatment of complex thoracic aortic lesions. However, some procedure-related complications have been reported, and spinal cord injury is one of the most important complications.
Our immune system has a fascinating ability to distinguish between what does or does not belong to our body. This ability allows it to fight off infectious agents without harming our own cells. T cells are key
Mechanosensitive Piezo channels are large membrane proteins present at the cell membrane of eukaryotic cells. These channels open in response to the presence of mechanical forces such as frictions that occur when extracellular fluids flow against the
New variants of porcine epidemic diarrhea virus with large deletions in the spike protein, identified in the United States
The Porcine Epidemic Diarrhea virus (PEDV) is an enveloped, positive-sense, single-stranded RNA virus that belongs to the genus Alphacoronavirus. This virus is known to only infect pigs and causes acute diarrhea, vomiting, and generally has a mortality
One of the most critical issues in orthopaedics is the development of a procedure for assessing fracture healing in an objective way and by means of a non-invasive approach, replacing the actual gold standard based on X-rays.
Invasive species are the organisms that cause significant economic or ecological damage in their non-native environment. Invasive species are considered the second biggest threat to global biodiversity after habitat degradation. These species threaten the stability and functioning
Phagocytosis is defined as the receptor-mediated uptake of large particulate matter. This process is particularly efficient in specialized immune cells such as macrophages, neutrophils and dendritic cells. These cells constitute the first line of defense against invading
Due to the lacking of a blood supply and the low cellular density of articular cartilage, this hard tissue has a limited healing capacity. Therefore, focal traumatic events causing cartilage defects rarely resolve spontaneously or are usually
Why study drop (or bubble) motions? Drops can be seen free, hanging, suspended in air, sessile, aggregating, coalescing, disintegrating/splitting or spreading in nature, in engineering processing or at home. Think about dew, fogs with drops of diameters
Asthma is a common chronic disease consisting of constriction and inflammation of the airways as well as structural changes known as remodelling (Fig. 1). 5-10% of patients have severe asthma, whereby symptoms persist despite regular and correct
Mental chronometry is commonly used to evaluate motor imagery ability. Mental chronometry measures imagined time required for movement. Smaller differences between imagined and actual times suggest higher motor imagery. Imagined and actual times for movement tend to
To what extent do childhood experiences of music practice influence thinking about music later in life? We could get an idea about this if we talk about childhood music memories while physiological recordings are made concomitantly. If we observe that there are clear
Acupuncture has been used to treat a wide range of health conditions. The efficacy of acupuncture has not conclusively been established because only randomized control trials using single-blind needles have been reported. Single blinding is problematic because