Category Archives: Research

Mesalamine for the prevention of recurrent diverticulitis?

AoS.Mesalamine for the prevention of recurrent diverticulitis?

Recurrent diverticulitis represents a relevant clinical problem, involving up to a quarter of patients after the first episode of diverticulitis. Unfortunately, there are no evidence-based data that indicate a targeted therapeutic approach for the prevention of recurrent

Soft-particle gel electrophoresis

AoS. Soft-particle gel electrophoresis.

Particle electrophoresis in free solution or in gel media is a powerful technique for characterizing the surface properties of colloidal particles. Particle gel electrophoresis, that is, transport processes of colloidal particles in polymer gel media under an

Developing aptamers and 21st century skills through innovative course-based aptamer research

Among the growing list of aptamer applications, innovative aptamer Course-Based Undergraduate Research Experiences (CUREs) have merged the scientific demand of aptamers with the positive student outcomes realized through authentic research experiences. This demand for additional aptamers is

Sheath blight of rice: challenges and management

Rice (Oryza sativa L) is one of the most widely consumed cereal crops, grown in more than a hundred countries. Around 40,000 different varieties of rice exist in the world, with China producing the largest amount of

Cryo-electron microscopy in drug development

AoS. Cryo-electron microscopy in drug development

Cryo-electron microscopy (cryo-EM) is becoming the method of choice in structure determination of membrane proteins and has great potential for structure-based drug discovery (SBDD). Cryo-EM provides high-resolution structural information of a membrane protein without the need for

TMEM165; The Bermuda triangle of glycosylation and Golgi Mn homeostasis

During evolution, eukaryotic cells have acquired a complex network of endomembranes delimiting distinct organelles with specific cellular functions. In mammals, the rough endoplasmic reticulum (ER) and the Golgi apparatus are two key organelles of the secretory pathway

Strong primary healthcare may reduce mortality

AoS. Strong primary healthcare may reduce mortality.

Healthcare is variably organized across the world. In some places, people attend medical specialists such as cardiologists and urologists directly. In other places, people attend primary care physicians for most health problems and, if necessary, they refer

Global climate change and mental health

AoS. Global climate change and mental health

In the past decade, several empirical studies and systematic reviews of the literature have documented the mental health impacts of global climate change.  However, the range of impacts and their relationship to specific forms of climate change

Atmospheric and genetic parameters influence Rhinovirus transmission

Rhinoviruses are a diverse set of very small and common viruses, repeatedly infecting humans in the course of a single year. For most people, infection usually results in mild common cold symptoms, and spontaneously resolves without the

Botulinum toxin and occupational therapy for Writer’s Cramp

AoS. Botulinum toxin and occupational therapy for Writer’s Cramp

Dystonia is a neurological disorder characterized by abnormal postures that interfere with making movements. Writer’s cramp is the most common type of dystonia involving the upper extremity. Patients initially experience painless loss of control while writing, discomfort

Can SEM/EDX analysis be useful in prosecution of medical malpractice?

AoS. Can sem/edx analysis be useful in prosecution of medical malpractice.

Forgetting surgical gauzes within a patient’s body after surgery is a serious matter but also sadly known to the newspapers. The retained gauzes may cause severe inflammatory reactions and numerous complications up to death; exceptionally, they can

Targeted GRP78 pathway for improved vision in diabetic retinopathy

AoS. Targeted GRP78 pathway for improved vision in diabetic retinopathy.

Diabetic retinopathy, is a complication of diabetes which causes vision loss and eventual blindness in adults. People with diabetes have more sugar in their blood than normal, which causes their bodies not to function correctly. Often proteins

A method for highly sensitive detection of D-amino acids

AoS. A method for highly sensitive detection of D-amino acids.

D-amino acids have recently attracted much attention in various research fields including medical, cliDical and food industry due to their important biological functions that differ from l-amino acid; thus, there has been an increasing need to develop

Nickel free, built-in nanotubular drug eluting stents

AoS. Ni-free, built-in nanotubular drug eluting stents

Coronary Artery Disease is a common cause of heart failure. Coronary Artery Disease (CAD) is caused by the accumulation of lipids and fats within an injured arteries’ walls and restricts the blood flow to the heart muscle

The suitability of scopolamine as an Alzheimer’s model

AoS.The suitability of scopolamine as an Alzheimer’s model

Alzheimer’s disease is the most common cause of dementia. About 50 million people worldwide have Alzheimer’s disease or a related form of dementia. Alzheimer’s disease is a terminal illness affecting mostly the elderly above the age of

Imaging metal nanoparticle adsorption on graphene aerogels

AoS. Imaging metal nanoparticle adsorption on graphene aerogels.

The functionalization of porous carbon aerogels and sponge-like materials with metal nanoparticles (NPs) has shown significant promise for several applications, including energy storage and harvesting and environmental remediation. Methods for imaging the internal structure of these porous

Impact of temperature on physicochemical and biological properties of silver-silica nanocomposite

AoS. Impact of temperature on physicochemical and biological properties.

The future of a well-known consumer world seems to be closely related to multifunctional engineering nanomaterials fulfilling a completely new role comparing them with the traditional structures and products. Such materials are inclined to sophisticated applications e.g.

Serum cytokine profile in mice after injection of supernatants of group A streptococci culture

Cytokines are involved in various pathophysiological processes of macroorganism, including regulation of immune response and inflammation. Numerous experiments have demonstrated that cytokines, necessary in small doses, may result in the development of “cytokine storm” when produced in

How mitochondria “sense” and respond to changes in oxygen concentration in vivo

AoS. How mitochondria sense

Mitochondria – intracellular organelles – are our organism’s “powerhouse”, the main oxygen sensors that play the signaling role as modulators of oxygen consumption and regulators of the rate of oxygen delivery from the extracellular environment. Changes in

How can we measure problematic videogame use among adolescents?

AoS. How can we measure problematic videogame use among adolescents?

Playing video games is currently one of the most frequent leisure activities in young people and adolescents, but it generates a social alarm because it is associated with negative consequences such as family or scholar problems, reduction