Category Archives: Research

Smart silk dressings – for treating chronic wounds

Breaching of integral structure of skin causes cutaneous wounds, healing of which becomes difficult in certain diseased or pathological conditions like diabetes, obesity, infection or traumatic injuries. According to the recent report from Diabetes Atlas, more than

Serious mental illness: accentuate the positive!

As the popular song implies, “accentuating the positive, spreading joy to the maximum” keeps stress at bay and improves mental health. Research in psychology has shown that it is not the presence or absence of fortunate events

The effect of birth date on gestation length in Holstein cows and heifers

This article is on an interesting subject which is worthy of investigation. In herd health management, knowing when to expect a calving is very important. So far, the influence of the month of calving on gestation length

A new kind of human immune cell that cannot leave the liver

Natural Killer (NK) cells are immune cells that are found in the blood and protect the body by killing infected and cancerous cells. NK cells can also be found in large numbers in some organs, including the

New therapy for the treatment of childhood bone cancer

Cancer in children and young adults is rare, with survival rates being very high, mainly depending on the treatment. The biggest proportion of this diagnosis will be on leukaemia and brain tumours, with just about 3% of

Super-resolution in live cells: Visualizing the molecular organization of the cell division machinery

We set out to elucidate the molecular organization of the proteins of the cytokinetic apparatus, an essential step to understanding the mechanism of cell division. Cytokinesis is best understood in the single cell model organism fission yeast.

A versatile in vitro bioassay for the screening of neurotrophic factor gene therapy systems to combat blindness

Glaucoma is the world’s second leading cause of blindness after cataracts, affecting about 80 million people worldwide annually. The disease is characterized by neurodegeneration involving a progressive visual field loss from the periphery towards the center, and

Acute immune responses in the brain differ from responses in blood

Immune cells of the brain called microglia, appear to have been adapted to their vulnerable environment. They react less destructive to danger signals than their counterparts in the blood. Microglia are the resident macrophages of the central

Manipulating a single microtubule by light

A cell is basically a miniature factory, which contains a large number of dedicated protein machines to perform various mechanical functions. For example kinesin is a linear motor protein which transport cargos such as organelles, chromosomes and

Measuring mineral levels in ultrapure concentrated acid: how hard can it be?

The short answer: hard. Concentrated acid is used in the semiconductor industry as a surface cleaning reagent. However, not every acid is good enough for this. The performance of electronic devices is highly sensitive to the presence

The dual role of mercury on mitochondrial complexes by sulfur bridges

All forms of mercury are long known to be highly toxic. In recent years, the metal occurrence in dental amalgams has raised worries for the harmful effects due to the slow mercury release in the human body.

How are thylakoid membranes shaped and maintained?

An oxygen-rich atmosphere was one of the most important prerequisites for the evolution of complex life on earth. Ancestors of modern-days cyanobacteria floated the earth’s atmosphere with this gas roughly 2.8 billion years ago. To convert carbon

Crowd surfing of graphene on a lipid monolayer

In the recent years a growing interest in graphene applications lead to the development of new biosensor devices. Graphene is a powerful sensor due to its extraordinary electron mobility, unique mechanical strength and optical properties.  Consequently, the

A novel mechanism by which viral integration drives cancer

Human papillomaviruses (HPV) are a group of about 200 DNA viruses that infect the skin, or the mucous membranes of the anus, genitals and oropharyngeal cavity. HPV infections are the most common sexually transmitted disease in the

What’s really in human milk? Studying microbiota in a novel body site

Breastfeeding is the gold standard of infant nutrition as it reduces children’s risk of developing obesity, asthma, allergies, diabetes, and numerous other medical conditions. This has been historically understood by the fact that breastmilk is rich in

Diving into cell membranes with advanced solid-state NMR methods: harnessing the power of protons

Membrane proteins act as the gateways of the cell. They are essential for the signalling between cells and for the uptake of nutrients; they constitute major drug-targets in human, and their malfunctions are related to severe diseases