Antibody based therapeutics have emerged as a key player in the management of diseases including cancer with majority of monoclonal antibodies (mAbs) belonging to the IgG class. Recently, increasing efforts have been made to develop non-IgG class
Los Angeles, CA – September 10, 2024 – Researchers at the University of California, Los Angeles (UCLA) have pioneered a groundbreaking approach in the imaging and detection of amyloid deposits in tissue samples. The innovative method leverages
Our cells respond to invading DNAs formed by viral infection in a variety of ways to suppress their ability to produce RNAs and proteins. One mechanism is to wrap the DNA with histones into a form of
Multiple sclerosis (MS) is an autoimmune disease where immune cells (T cells) and antibodies progressively damage the myelin sheath surrounding nerve cells leading to their loss of function. We have a reasonable understanding of the disease process
A significant advancement for point-of-care medical diagnostics, a team of researchers from UCLA has introduced a deep learning-enhanced, paper-based vertical flow assay (VFA) capable of detecting cardiac troponin I (cTnI) with high sensitivity. The innovative assay holds
Despite appearances, bones are a constantly changing organ in the body. Cells that produce new bone (named osteoblasts) and cells that break down bone (named osteoclasts) work in harmony to ensure that old bone is continuously replaced,
Psychiatry is a nuanced specialty that relies on body language and subtle nonverbal cues from patients. As such, when using simulation to teach medical students, standardized patients are considered the gold standard. Standardized patients are actors who
Frequently the harsh environmental conditions, such as, high temperatures, low freezing conditions, high levels of PAR and UV-B sun radiation induce remarkable adaptive reactions in plants. These responses suggest that plants may possess genes associated with defence
Sewers might be out of sight, but they play a huge role in shaping the well-being of a society. They quietly carry away all the wastewater from our homes, businesses, and factories, preventing harmful viruses, bacteria, and
Sleep abnormalities are commonly observed in individuals with schizophrenia and related psychotic disorders. Research shows that over half of people with these conditions have trouble sleeping. Poor sleep also often contributes to the development and worsening of
Highly enriched isotopes such as 10B, 98Mo, and 100Mo are in great demand for the manufacturing of radioactive isotopes for medical diagnostic imaging studies and therapeutic applications. In order to produce useful quantities of the medical radioisotopes,
A second trimester miscarriage is the spontaneous loss of a pregnancy between 12 and 22 weeks of pregnancy. This is indeed a very sad experience to the parents. It has been said that a miscarriage may cause
Some of the most enduring images for a molecular biologist are electron microscopy micrographs of the so-called “Christmas trees”, famously first observed by Oscar Miller from newt oocytes in 1969. These intriguing structures (Fig. 1A) capture the
Within a breeding colony of rabbits, the American pathologist Harry Greene (1904-1969) observed that mammary carcinomas were restricted to certain families. This is suggestive of a familiar predisposition as it occurs in human breast cancer. In rabbits,
Glucocorticoids are medications widely used to treat inflammation and allergies, and in contexts of immunosuppression such as after transplants. They are well-established and safe. The problem is that, when used for a long time, or in high
Atherosclerosis is a chronic medical condition characterised by the accumulation of fat in the walls of blood vessels, which obstruct the normal flow of oxygen-rich blood and can have severe health consequences. Peripheral arterial disease (PAD) is
Obesity typically occurs when a person eats more calories than they need for their daily activity. It results in a build-up of fatty tissue around all organs. In lean people, fat tissues work closely with hormones to
The prevalence of Alzheimer’s disease (AD), the most common cause of dementia nowadays, is expected to increase within the coming years, representing a serious threat for society and the healthcare system. For this reason, a lot of
Rheumatoid Arthritis (RA) is a common inflammatory disease that is characterized by swelling and tenderness of multiple joints. The resulting pain and joint stiffness cause disability for patients and treatment to control the inflammation is required to
Juvenile localized scleroderma, also known as morphea, is an rare condition, it occurs around 1 in 5000 children, where the skin and the tissues underneath the skin like fat tissue, muscle, tendons, and bone, get inflamed and
The NucleoCounter® NC-3000™ is an advanced image cytometer utilizing fluorescence Read More »
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