Tag Archives: α-synuclein

Truncation: A possible mechanism for diversity in Alpha-synuclein prion-like properties

Truncation: A possible mechanism for diversity. AoS

Parkinson’s disease (PD) is the most common neurodegenerative movement disorder, which is characterized by motor disturbances such as tremor and bradykinesia resulting from severe degeneration of nigral dopaminergic neurons. The pathological hallmark of PD is the presence

How reducing cell signalling protects neurons against synapse degeneration

Dementia is a clinical manifestation of Alzheimer’s disease, dementia with Lewy bodies and is seen in a high proportion of late stage Parkinson’s disease patients. The symptoms are associated with degeneration of synapses, the structures by which