Tag Archives: acetylcholine

Parkinson disease: a tale of three neurotransmitters

The progressive loss of dopaminergic innervation of the basal ganglia, in particular of the dorsal striatum (putamen) is responsible for the motor signs of Parkinson disease such as bradykinesia, rigidity and loss of postural reflexes. Present therapies

RIC-3’s effect on nicotinic acetylcholine receptors (nAChRs) and the implications in health and disease

Signal transmission – cells sending and receiving signals from other cells – is the basis of physiology. Everything our body does essentially, is a result of this cell-to-cell communication and innumerable diseases are the results of this

The heart’s own acetylcholine important in health and disease

Tissues and organs of our body are under the control of active chemical compounds. Hormons are released from  endocrine glands and reach the targets with blood.  Transmitters are released from the endings of nerve fibers. If the

Compounds earlier known as neurotransmitters are met and function in every living organism

Historically, the neurotransmitters function were analyzed only in animals with nervous system, and their initial role was associated mainly with the transmission of nerve (electrical) impulses. In the last decade of the 20 century, new views on

Septo-hippocampal signal processing

If we are ultimately to uncover how the brain encodes the information about the surrounding environment it is necessary to understand how the spatial signals are being processed and regulated. The hippocampal region plays a crucial role