Tag Archives: Alzheimer

Repetitive DNA in the ABCA7 gene influences Alzheimer’s disease

Repetitive DNA in the ABCA7 gene influences Alzheimer’s disease

Dementia, which is characterized by decline of memory or other cognitive traits to the extent that a person’s daily functioning is affected, is one of the most important global health challenges of our time. Approximately 50 million

Novel perspectives for the Alzheimer´s disease therapy in a multitargeted approach

Alzheimer´s disease (AD) is the most wide-spread neurodegenerative disease and develops to a main problem for a society in which the people get older and older as a result of improved drug developments and therapies. The benefit

DNAJB6 – an early-stage scavenger of amyloidogenic peptides

A molecular chaperone has been discovered that binds to amyloidogenic peptides and delays onset of aggregation and neurodegeneration. Chaperone proteins, existing in the cells of all organisms, are helper proteins that serve to keep the proteins in

Mutations in the SORL1 gene affect risk of early-onset Alzheimer’s disease

Alzheimer’s disease (AD) is the most common cause of dementia, leading to an enormous burden on societies worldwide. In brains of patients with AD, abnormal tangles of a protein called tau are found within nerve cells, in

Comparison of the effect of exercise on late-phase LTP of the dentate gyrus and CA1 of Alzheimer’s disease model

There has been a recent upsurge of scientific reports about the benefits of regular physical exercise for general health and particularly for mental health.  Healthy diet and physical activity have emerged as promising low-cost measures for protection

The potential of chitosan in prevention and treatment of age-related diseases

According to the recent report of The Department of Economic and Social Affairs of the United Nations Secretariat the number of elderly (aged 60 years or over) is expected to increase from 841 million people in 2013