Tag Archives: Alzheimer

The suitability of scopolamine as an Alzheimer’s model

AoS.The suitability of scopolamine as an Alzheimer’s model

Alzheimer’s disease is the most common cause of dementia. About 50 million people worldwide have Alzheimer’s disease or a related form of dementia. Alzheimer’s disease is a terminal illness affecting mostly the elderly above the age of

Physiological brainwashing

Physiological brainwashing. AoS

There is a barrier in the brain, known as the blood-brain barrier, which strictly regulates the exchange of substances between the blood and this organ. The blood-brain barrier restricts the passage of drugs into the brain and

Most common behavioral problems in people with dementia

Most common behavioral problems in people with dementia. AoS

With people all over the world living longer, more and more of them develop problems with brain functions. Some of these problems are mild, e.g. slight forgetfulness, but some may interfere with their daily activities, such as

A mass spectrometry view of the interaction of Alzheimer’s disease proteins with an anti-aggregation compound

Alzheimer’s disease is a neurodegenerative disease that has been studied extensively over the last four decades. Millions of people worldwide are affected by this disease, and because our population is growing older, this disease is becoming alarmingly

Biomarkers for Alzheimer’s disease diagnosis: an eye on retinal inflammation

Biomarkers for Alzheimer’s disease diagnosis. AoS

Alzheimer’s disease is one of the most common neurodegenerative disorders. Alzheimer’s disease cases are constantly increasing worldwide due to population aging. Typical symptoms of the disease include memory loss, cognitive deficits, personality and behavior modifications. At the

Repetitive DNA in the ABCA7 gene influences Alzheimer’s disease

Repetitive DNA in the ABCA7 gene influences Alzheimer’s disease

Dementia, which is characterized by decline of memory or other cognitive traits to the extent that a person’s daily functioning is affected, is one of the most important global health challenges of our time. Approximately 50 million

Novel perspectives for the Alzheimer´s disease therapy in a multitargeted approach

Alzheimer´s disease (AD) is the most wide-spread neurodegenerative disease and develops to a main problem for a society in which the people get older and older as a result of improved drug developments and therapies. The benefit

DNAJB6 – an early-stage scavenger of amyloidogenic peptides

A molecular chaperone has been discovered that binds to amyloidogenic peptides and delays onset of aggregation and neurodegeneration. Chaperone proteins, existing in the cells of all organisms, are helper proteins that serve to keep the proteins in

Mutations in the SORL1 gene affect risk of early-onset Alzheimer’s disease

Alzheimer’s disease (AD) is the most common cause of dementia, leading to an enormous burden on societies worldwide. In brains of patients with AD, abnormal tangles of a protein called tau are found within nerve cells, in

Comparison of the effect of exercise on late-phase LTP of the dentate gyrus and CA1 of Alzheimer’s disease model

There has been a recent upsurge of scientific reports about the benefits of regular physical exercise for general health and particularly for mental health.  Healthy diet and physical activity have emerged as promising low-cost measures for protection

The potential of chitosan in prevention and treatment of age-related diseases

According to the recent report of The Department of Economic and Social Affairs of the United Nations Secretariat the number of elderly (aged 60 years or over) is expected to increase from 841 million people in 2013