Tag Archives: AMPK
Role of AMPK and PKA pathways in chicken spermatozoa functions
Spermatozoa functions include delicate and high energy consuming processes like motility and the ability to perform acrosome reaction, i.e. the fusion of the spermatozoa head cytoplasmic membrane and the underlying outer acrosomal membrane, so that the acrosome
Hibernating chipmunk’s brain senses loss of energy
The vast majority of mammals maintain their body temperature around 40°C throughout their lifetimes; however, hibernating mammals are an exception. Hibernation is an important adaptation to survive harsh conditions, such as frigid environments or starvation. It is
Cellular stress and AMPK activators including metformin and the anesthetic drug propofol promote restoration of human consciousness
The neural mechanisms that give rise to human consciousness have been described as one of the greatest and most profound mysteries in all of modern medicine. The use of general anesthetics to induce loss of consciousness (LOC)
Cellular stress and AMPK links metformin and jumping genes with the creation of human life
The evolution of the human genome has been facilitated to a great extent by the activity of transposable elements (TEs), also known as “jumping genes”. As the name implies, TEs are DNA sequences capable of moving or
Metformin and AMPK link cancer stem cell elimination with the potential eradication of HIV
Cancer stem cells (CSCs) are cancer cells that exhibit several stem cell-like qualities that are characteristic of embryonic or adult stem cells, including self-renewal, differentiation, and the ability to initiate tumorigenesis. CSCs, similar to adult stem cells
Oocyte activation and latent HIV-1 reactivation: AMPK links the creation of all human life and the potential eradication of HIV-1
In an active area of research known as HIV-1 cure research, the purposeful reactivation of latent/dormant HIV-1 in memory T cells, which induces death of the infected cell or alerts the immune system to the presence of
AMPK: How can we amp it up to fight disease?
The high prevalence of obesity, insulin resistance, type 2 diabetes and cardiovascular disease has made it clear that we need a better understanding of how our bodies store and use energy when we overload them with excess
AMPK, an energy consumption supervisor, regulates hedgehog and may be a cancer therapeutic target
A cell can be thought of as a factory with many machines controlling different processes. Cell growth is the process by which a cell divides and multiplies. It is a highly energy-consuming process. Therefore, supervisors are needed
