Tag Archives: amyloid fibrils
New morphology of amyloid fibrils
It has been shown earlier that one of the proteins from the Saccharomyces cerevisiae cell wall (glucantransferase Bgl2) forms amyloid structures after isolation from cell wall under acid pH conditions. It is known that the acid treatment
Determination of the size of folding nuclei of fibrils formed from Aβ(1-40) peptide
One of the most important models for studying amyloid fibril formation is the Aβ peptide, aggregates of which form plaques in the course of Alzheimer`s disease. Formation of Aβ aggregates goes through the nucleation mechanism with exponential
Oligomers are building blocks of amyloid formation for insulin and its fast analog LisPro
The hormone insulin was discovered in 1921 by Banting and Best, and since that time it has been studied rigorously. At the same time first attempts were made to use insulin for treating diabetes. Insulin was the
One of the mechanisms of amyloid fibrils formation based on the sizes of folding nuclei of Aβ40 and Aβ42
Antibiotics and various advances in medical treatment have led to overall growth of life expectancy. However, along with positive aspects of prolonged life, humanity has faced a new challenge – age-related deceases. Parkinson’s disease along with Alzheimer’s
