Tag Archives: animal models
Improving assessment of arthritis models to better reflect human symptoms of disease
Rheumatoid Arthritis (RA) is a common inflammatory disease that is characterized by swelling and tenderness of multiple joints. The resulting pain and joint stiffness cause disability for patients and treatment to control the inflammation is required to
Intracranial injections and animal models: towards understanding and treating human disease
The use of laboratory animals helped us to better understand a myriad of biological processes in health and disease and enabled the development of therapies that effectively cure, or ameliorate life conditions of, millions of people every
Zebrafish is an attractive model to anticipate drug-induced renal injury in humans
Most of the innovative drugs with important therapeutic benefits are not approved or are removed from the clinical practice due to drug-induced toxicity. The kidneys are one of the most important target organs of drug toxicity because
Epileptic encephalopathies in children: Animal models may change the word “catastrophic” to “hopeful”
Seizures are a sign of brain dysfunction caused by abnormal, hyperexcitable brain circuits. Clinical seizures range from brief staring spells to massive whole – body convulsions. The developing brain is especially prone to seizures and seizure-related brain
Oxytocin and human Central Diabetes Insipidus in relation to the different hydromineral animal models
Central Diabetes Insipidus (CDI) is a disorder caused by a deficit in the production of arginine vasopressin (AVP), a hormone that acts by binding to AVP receptor 2 (AVPR2) on the kidney collecting tubule cells and produces
Understanding the dog model of Duchenne muscular dystrophy
Animal models are indispensible in the development of novel therapies. A clear understanding of the model itself is essential before the model is used in research. This means we need to know every aspect of the model
