Tag Archives: arthritis
Unlocking new treatments for bone diseases: using PEPITEM to strengthen bones and prevent loss
Despite appearances, bones are a constantly changing organ in the body. Cells that produce new bone (named osteoblasts) and cells that break down bone (named osteoclasts) work in harmony to ensure that old bone is continuously replaced,
Improving assessment of arthritis models to better reflect human symptoms of disease
Rheumatoid Arthritis (RA) is a common inflammatory disease that is characterized by swelling and tenderness of multiple joints. The resulting pain and joint stiffness cause disability for patients and treatment to control the inflammation is required to
Diagnostics of seronegative rheumatoid arthritis using glycomic tools and machine learning
Rheumatoid arthritis (RA) is an inflammatory disease characterized by synovium swelling and destruction. There are two different types of rheumatoid arthritis, sometimes even believed to be two distinct disorders, namely seropositive (S+) and seronegative (S-) rheumatoid arthritis.
Does body mass index affect how well patients do after meniscus surgery?
Obesity is present in about 38% of adults in the United States, and as many as 67% of patients with knee injuries (including meniscus tears). Some research has shown that obese patients have worse function and more
Gut microbiota: A potential trigger of rheumatoid arthritis
Rheumatoid arthritis (RA) is a chronic systemic inflammatory disorder characterized by synovitis in multiple joints and systemic comorbidities. Both genetic and environmental agents are thought to be the risk factors for arthritis. Recent studies have suggested that
Can Radon radiation become a source of treatment for Rheumatoid Arthritis?
Rheumatoid arthritis (RA) is the most common type of autoimmune disease. It is triggered by a faulty immune system of the body. However, the real cause of the disease is not completely known. The disease affects the
Clinical studies ask: “Are less expensive ‘biosimilar’ drugs as effective and safe as current drugs?”
Several debilitating diseases caused by disorders in a patient’s immune system – often called ‘immune-mediated diseases’ – have become easier to treat in the last two decades following the discovery of drugs called ‘biologics’. Biologics act on
Collagen V2.0: A system for re-engineering human type II collagen
Collagen is the main structural component in animals, making up approximately 30% of the total protein in our bodies. Collagen is an integral component of skin, tendon, bones, cartilage, and the placenta. Modern methods in cell biology
The undiagnosed, untreated key to restoring physical function and health in rheumatoid arthritis patients
Rheumatoid arthritis (RA) is characterised by adverse changes in body composition – specifically, reduced muscle mass (MM) and increased fat mass (FM). Indeed, when body composition is assessed (i.e. MM and FM are estimated), significant muscle loss
Blogging as a research methodology
The Arthriting study, the larger study this paper is from, was done to improve our understanding of the daily experiences of young people (aged 11-19) with juvenile idiopathic arthritis (JIA), the commonest type of arthritis in young
Epstein–Barr virus in peripheral blood predicts response to rituximab therapy in rheumatoid arthritis
Rheumatoid arthritis (RA) is an autoimmune disease, characterized by chronic inflammation of the joints that may cause permanent cartilage and bone damage. The cause of RA is unknown. It is, however, believed that a combination of genes
Posterior cervical fusion may lessen spinal cord compression in patients with rheumatoid arthritis
Patients with rheumatoid arthritis may develop inflammation of the joints in the spine, just as they develop inflammation of joints in their hands, feet, and others. The joint between the first cervical vertebra (C1) and the second
Changing the image of Gout
Gout is the most common arthritis of patients over 40 years of age. Many phycians treat these gouty attacks but do not realize that they should also care for the underlying urate accumulation. It is not only
A novel approach for the treatment of Juvenile Idiopathic Arthritis and possibly other autoimmune diseases.
Juvenile Idiopathic Arthritis (JIA) is a leading chronic autoimmune disease in children that can result in severe disability, pain, and loss of quality of life. Similarly to what is found in other autoimmune diseases, the immune-balance in
